Alcoholic cardiomyopathy

Table 1 Key studies on the long-term prognosis of alcoholic cardiomyopathy

Ref.	Definition alcohol intake/cardiopathy criteria	Number of patients	NYHA III-IV	% Abstinent	Follow-up	Mortality or heart transplant
McDonald et al[69]	> 6 beers/d or 2 quarts of wine/wk or 1 fifth of whisky/wk (44 patients consumed > 6 yr) Cardiomegaly with HF signs or symptoms	48	N/A	N/A	N/A	40%
Demakis et al[70]	> 8 oz or 1 L wine or 2 L of beer (ca. 90 g) ≥ 5 yr < 50 years old, HF and cardiothoracic ratio > 0.5	57	100%	31%	40.5 mo	57% in persistent drinkers 24% in non-drinkers
Haissaguerre et al[9]	> 80 g/d; ≥ 5 yr LVEF< 55% or LVEF 55%-59% and LVEDV 115 mL/m2	110	N/A	44%	38.8 mo	50% in persistent drinkers 6% in non-drinkers
Prazak et al[12]	> 80 g/d; ≥ 5 yr Heart failure and LVEF < 50%	23	52%	N/A	N/A	19% (10-yr survival)
Fauchier et al[11]	> 80 g/d; ≥ 5 yr DCM: WHO definition and hospitalization or arrhythmia	50	44%	45%	47 ± 40 mo	50% non-drinkers 70% in persistent drinkers
Gavazzi et al[10]	> 80 g/d; ≥ 5 yr or 100 mg/d 2 yr LVEF < 50 and HF or arrhythmia	79	35%	74%	59 ± 35 mo	Overall: 59% 55% in non-drinkers, 73% in persistent drinkers

HF: Heart failure; LVEF: Left ventricular ejection fraction; LVEDV: Left ventricular end-diastolic volume; DCM: Dilated cardiomyopathy; WHO: World Health Organization.