Complete regression of myocardial involvement associated with lymphoma following chemotherapy

Table 1 Characteristics of 7 reported cases of cardiac metastatic lymphoma

Ref.	Age/sex	Symptoms	Type of lymphoma	Localization in heart	Diagnostic tools	Therapy and evolution
Wiernik et al[12]	42/M	Ureteral obstruction Acute myocardial infarction Heart failure	Lymphocytic lymphoma	Gross infiltration of the lateral wall of the left ventricle	Autopsy	Chemotherapy Radiotherapy Died 9 yr later
Lestuzzi et al[13]	23/F	None	Lymphoblastic lymphoma	Cardiac apex	2D-echo	Local radiotherapy Died 12 mo later
	53/F	Dyspnea	Burkitt’s lymphoma	Epicardium, posterior ventricular wall and interventricular septum	2D-echo	Local radiotherapy Died 20 d later
Lynch et al[14]	NA	NA	NA	Pericardial and myocardial	NA	Chemotherapy
Cracowski et al[15]	25/M	Dyspnea	High grade malignant lymphoma	Left ventricular hypertrophy with increased echogenicity of the myocardial walls and marked decrease in left ventricular ejection fraction	2D-echo, EMB	Chemotherapy
Cho et al[16]	39/F	Dyspnea and palpitation	Diffuse large cell type non-Hodgkin's lymphoma	Interventricular septum and left ventricular posterior wall	2D-echo	Chemotherapy
Bergler-Klein et al[17]	34/F	None	Burkitt’s lymphoma	Asymmetric hypertrophy of the mid and distal septum with a speckled appearance of the myocardium and LV apical region	2D-echo MRI, PET	Chemotherapy Died 9 mo later
Vinicki et al	26/M	Testicular mass and unilateral peripheral facial paralysis	T-cell lymphoblastic lymphoma	Pericardial, aorta, both atrial and the interatrial septum	2D-echo	Chemotherapy Died 4 mo later

2D-echo: Two-dimensional echocardiography; EMB: Endomyocardial biopsy; F: Female; M:Male; MRI: Magnetic resonance imaging; NA: Not applied.