Blood cellular mutant LXR-α protein stability governs initiation of coronary heart disease

Table 1 Laboratory variables of subjects employed in the study

	Control(n = 10)	CHD subjects(n = 40)	P value
Age (yr)	51 ± 8	53 ± 4	NS
Sex	M	M	NA
TC (mg/dL)	179.5 ± 4.7	182.0 ± 3.6	NS
TG (mg/dL)	156.2 ± 6.3	167.1 ± 8.7	NS
HDL-C (mg/dL)	49.8 ± 1.3	42.6 ± 3.9	NS
LDL-C (mg/dL)	93.24 ± 5.67	102.0 ± 5.3	NS
Serum CRP (mg/dL)	0.63 ± 0.32	1.10 ± 0.51	NS
Serum 25 (OH) Vitamin D3 (ng/mL)	16 ± 2.3	7.3 ± 3.2	S

CHD: Coronary heart disease; TC: Total cholesterol; TG: Triglyceride; HDL-C: High-density lipoprotein cholesterol; LDL-C: Low-density lipoprotein cholesterol; M: Male; NS: Not significant; NA: Not applicable; S: Significant; CRP: C-reactive protein.

Table 2 Subject groups formed on the basis of severity of coronary occlusion as measured by gensini score

Group	Gensini score	No. of subjects
Control	0	10
Group I	1-10	10
Group II	11-20	10
Group III	21-30	10
Group IV	> 30	10