Retrospective Cohort Study
Copyright ©The Author(s) 2025.
World J Cardiol. Apr 26, 2025; 17(4): 102669
Published online Apr 26, 2025. doi: 10.4330/wjc.v17.i4.102669
Table 1 Cohort characteristics, median (25th-75th percentiles)

Sutured (n = 808)
Perceval (n = 174)
P value
Demographics
Age (n = 982)70 (64-76)77 (74-80)< 0.001
Gender (n = 982)< 0.001
Male520 (64.4)70 (40.2)
Female288 (35.6)104 (59.8)
BMI (n = 982)28.4 (25.0-32.4)29.0 (25.6-32.8)0.165
Smoking status (n = 848)0.024
Non-smoker334 (41.3)65 (37.4)
Ex-smoker 279 (34.5)76 (43.7)
Current smoker 86 (10.6)8 (4.6)
Diabetes (n = 982)0.002
No659 (81.6)124 (71.3)
Diet38 (4.7)7 (4.0)
Oral therapy79 (9.8)27 (15.5)
Insulin32 (4.0)16 (9.2)
NYHA grade (n = 879)0.148
Grade I 144 (17.8)21 (12.1)
Grade II208 (25.7)37 (21.3)
Grade III282 (34.9)69 (39.7)
Grade IV 93 (11.5)25 (14.4)
Cardiovascular risk factors
Heart rhythm (n = 914)0.54
Sinus rhythm 607 (80.8)129 (79.1)
Atrial fibrillation/flutter123 (16.4)32 (19.6)
Complete heart block/pacing11 (1.5)2 (1.2)
Other dysrhythmia9 (1.2)0 (0.0)
Hypertension (n = 882)511 (63.2)126 (72.4)0.022
CCS angina status (n = 858)0.863
CCS0422 (59.1)79 (54.9)
CCS183 (11.6)19 (13.2)
CCS295 (13.3)23 (16.0)
CCS382 (11.5)16 (11.1)
CCS432 (4.5)7 (4.9)
LVEF (n = 681)0.578
Good (> 50%)424 (75.7)92 (76.0)
Moderate (21%-30%)109 (19.5)22 (18.2)
Poor (31%-50%)22 (3.9)7 (5.8)
Very poor (< 25%)5 (0.9)0 (0.0)
Previous MI (n = 918)62 (8.2)12 (7.5)0.794
Reoperation procedure (n = 982)42 (5.2)7 (4.0)0.518
Risk scores
Additive Euroscore (n = 980)5.00 (1.88-7.00)6.00 (2.22-7.00)0.003
Logistic Euroscore (n = 600)5.28 (3.29-8.56)7.01 (5.48-10.27)< 0.001
Table 2 Intra-operative details before and after propensity matching, median (25th-75th percentiles)
Before propensity score matching
After propensity score matching

Sutured
Perceval
P value
Sutured
Perceval
P value
Bypass time (minutes) (n = 925)93.0 (72.0-123)60.0 (49.0-78.0)< 0.00187.0 (69.0-112)60.0 (49.0-78.0)< 0.001
Cross-clamp time (minutes) (n = 924)75.0 (58.0-99.0)45.5 (36.0-57.0)< 0.00171.0 (56.0-90.6)45.5 (36.0-57.0)< 0.001
Time Ventilated (hours) (n = 873)11.5 (7.6-19.0)9.9 (7.3-17.9)0.38313.6 (9.35-20.5)9.88 (7.33-17.9)0.005
Time in theatre (minutes) (n = 981)180 (153-215)139 (119-165)< 0.001171 (143-201)139 (119-165)< 0.001
Table 3 Immediate post-operative outcomes before and after propensity score matching, median (25th-75th percentiles)
Before propensity score matching
After propensity score matching
Odds ratio1

Sutured valves
Perceval valves
P value
Sutured valves
Perceval valves
P value
Intra-operative mortality 0 (0.0)0 (0.0)NA0 (0.0)0 (0.0)NANA
In-hospital mortality 16 (2.0)1 (0.6)0.1972 (1.1)1 (0.6)0.5620.50 (0.04-5.55)
< 30 days mortality 23 (2.8)3 (1.7)0.4034 (2.3)3 (1.7)0.7030.73 (0.16-3.35)
Length of CICU stay (days) (n = 917)1.14 (0.97-2.11)1.13 (0.98-1.91)0.5431.25 (1.00-2.50)1.13 (0.96-2.00)0.132NA
Total length of stay (days) (n = 917)6.90 (5.31-9.99)7.08 (5.93-9.90)0.2488 (6.00-11.0)7 (6.00-10.00)0.315NA
Post-operative complications
Atrial fibrillation229 (28.3)39 (22.4)0.11158 (33.3)39 (22.4)0.0230.57 (0.35-0.91)
Pneumonia 152 (18.8)21 (12.1)0.03036 (20.7)21 (12.1)0.0300.49 (0.27-0.90)
Delirium 100 (12.4)28 (16.1)0.18727 (15.5)28 (16.1)0.8831.03 (0.58-1.83)
MI1 (0.1)0 (0.0)0.6420 (0.0)0 (0.0)NANA
PPM19 (2.4)6 (3.4)0.4054 (3.10)6 (3.4)0.5211.50 (0.42-5.44)
VT/VF9 (1.1)0 (0.0)0.1620 (0.0)0 (0.0)NA0.94 (0.06-15.9)
Pneumothorax 8 (1.0)1 (0.6)0.6021 (0.6)1 (0.60)1.0000.95 (0.06-15.89)
Stroke 25 (3.1)6 (3.4)0.8084 (2.3)6 (3.4)0.5211.51 (0.42-5.47)