Retrospective Study
Copyright ©The Author(s) 2023.
World J Cardiol. Mar 26, 2023; 15(3): 84-94
Published online Mar 26, 2023. doi: 10.4330/wjc.v15.i3.84
Table 1 Demographic baseline and clinical characteristics
Characteristics
FlexyRap® cobalt chromium rapamycin eluting coronary stent system; Number of patients, (n = 500)
Patient demographics
Age, yr (mean ± SD)59.30 ± 11.27
Male, n (%)351 (70.2)
Female, n (%)149 (29.8)
Heart rate (mean ± SD)86.36 ± 11.34
Systolic blood pressure (mean ± SD)133.57 ± 20.88
Diastolic blood pressure (mean ± SD)83.36 ± 9.70
Haemoglobin (g/dL) (mean ± SD)12.64 ± 2.45
Platelet count (mean ± SD)205.85 ± 52.19
Baseline medical history, n (%)
Hypertension217 (43.4)
Smoking current203 (40.6)
Diabetes mellitus70 (14)
Alcohol current48 (9.6)
Dyslipidemia17 (3.4)
Previous MI274 (54.8)
History of CAD24 (4.8)
Previous PCI21 (4.2)
Previous Stroke9 (1.8)
Baseline cardiac history, n (%)
Stable angina299 (59.8)
Unstable angina201 (40.2)
Angina class, n (%)
Class I12 (2.4)
Class II30 (6)
Class IIA1 (0.2)
Class IIB12 (2.4)
Class IIC6 (1.2)
Class III198 (39.6)
Class IIIA15 (3)
Class IIIB51 (10.2)
Class IIIC37 (7.4)
Class IV138 (27.6)
Disease vessel, n (%)
Single vessel314 (62.8)
Double vessel150 (30)
Triple vessel27 (5.4)
Quadra vessel9 (1.8)
LVEF (mean ± SD)52.88 ± 15.46
Serum creatinine (mean ± SD)1.47 ± 0.47
CABG: Coronary artery bypass graft; CAD: Coronary artery disease; LVEF: Left ventricular ejection fracture; MI: Myocardial infarction; PCI: Percutaneous coronary intervention.
Table 2 Procedural characteristics
Procedural characteristics (n = 500)
Lesion details
Total number of lesions treated with FlexyRap® (n)730
Total number of stents deployed (n)730
Total stent per lesion (n = 500 patients) (Total no. stent deployed (730)/Total lesion locations (729)1.001
Total lesion per vessel (n = 500 patients); Total lesion locations (729)/(Sum of total No of diseased vessel (731)0.997
Lesion locations (729) n (%)
D16 (0.82)
Distal LAD17 (2.33)
Distal LCx4 (0.54)
Distal RCA16 (2.19)
LAD279 (38.27)
LCx98 (13.44)
LM1 (0.13)
MID LAD19 (2.6)
MID LCx9 (1.23)
MID RCA15 (2.05)
O Mid7 (0.96)
OM4 (0.54)
OM18 (1.09)
OM26 (0.82)
OM31 (0.13)
OMI1 (0.13)
Osteoproximal LAD2 (0.27)
Osteoproximal RCA4 (0.54)
PDA7 (0.96)
PLV3 (0.41)
Proximal LAD23 (3.15)
Proximal RCA15 (2.05)
Proximal LCx7 (0.96)
PTCA8 (1.09)
Ramus intermedius8 (1.09)
RCA156 (21.40)
RCX2 (0.27)
PLB2 (0.27)
POM1 (0.13)
Stent length (mean ± SD)26.03 ± 10.86
Stent diameter (mean ± SD)3.06 ± 0.41
Type of stenosis, n (%)
de novo500 (100)
Thrombus load (n = 731), n (%)
None519 (71)
Mild90 (12.31)
Moderate59 (8.07)
Severe63 (8.62)
Lesion type [ACC/AHA classification] (n = 731), n (%)
Type A20 (2.73)
Type B1193 (26.40)
Type B2302 (41.31)
Type C216 (29.55)
Stent balloon inflation pressure (atm) (mean ± SD) (n = 500)12.52 ± 1.75
TIMI FLOW n (%)
II9 (1.8)
III491 (98.2)
% of occlusion (mean ± SD) (n = 500)88.60 ± 8.79
All values are presented in n (%) or mean ± SD
ACC/AHA: American college of cardiology/American heart association; LAD: Left anterior descending artery; LCx-: Left circumflex; LM: Left main; OM: Obtuse marginal artery; PDA: Patent ductus arteriosus; PLV: Posterior left ventricular artery; PTCA: Percutaneous transluminal coronary angioplasty; PLB: Posterolateral branch; POM: Medial preoptic nucleus; RCAL Right coronary arterial ligation; RCX: Right Circumflex artery; SD: Standard deviation; TIMI: Thrombolysis in myocardial infarction.
Table 3 Cardiac event rate, n (%)
Clinical event12-mo (n = 500)3-yr (n = 500)5-yr (n = 500)
TLF0 (0)0 (0)0 (0)
Cardiovascular Death0 (0)0 (0)0 (0)
TV-MI1 (0.2)0 (0)1 (0.2)
Clinically-driven TLR0 (0)0 (0)0 (0)
Late ST2 (0.4)0 (0)0 (0)
TVF0 (0)0 (0)0 (0)
TVR0 (0)0 (0)0 (0)
Very late ST0 (0)2 (0.4)0 (0)
Total MACE1 (0.2)0 (0)1 (0.2)
MACE: Major adverse cardiac event; TLF: Target lesion failure; TV-MI: Target vessel myocardial infarction; TLR: Target lesion revascularization; ST: Stent thrombosis; TVF: Target vessel failure; TVR: Target vessel revascularization.