Comparative assessment of clinical profile and outcomes after primary percutaneous coronary intervention in young patients with single vs multivessel disease

Table 1 Baseline clinical and demographic characteristics stratified by number of vessels involved, n (%)

Characteristics	Total	Involved vessels		P value
		Single vessel	Multivessel
Total	571	342 (59.9)	229 (40.1)	-
Clinical characteristics
Age (mean ± SD, yr)	39.04 ± 4.86	38.24 ± 5.18	40.24 ± 4.06	< 0.001
Body mass index (mean ± SD, kg/m2)	26.24 ± 4.01	26.25 ± 4.07	26.22 ± 3.94	0.929
Male gender	501 (87.7)	303 (88.6)	198 (86.5)	0.446
Hypertension	173 (30.3)	86 (25.1)	87 (38)	0.001
Diabetes	103 (18)	40 (11.7)	63 (27.5)	< 0.001
Positive family history	41 (7.2)	27 (7.9)	14 (6.1)	0.419
Smoking	189 (33.1)	124 (36.3)	65 (28.4)	0.050
Obesity	89 (15.6)	55 (16.1)	34 (14.8)	0.690
CCS angina grade (within past two weeks)
No symptoms, no angina	272 (47.6)	158 (46.2)	114 (49.8)	0.367
CCS I	33 (5.8)	22 (6.4)	11 (4.8)
CCS II	66 (11.6)	35 (10.2)	31 (13.5)
CCS III	105 (18.4)	70 (20.5)	35 (15.3)
CCS IV	95 (16.6)	57 (16.7)	38 (16.6)

CCS: Canadian Cardiovascular Society.

Table 2 Angiographic and pre-procedural characteristics stratified by number of vessels involved, n (%)

Characteristics	Total	Involved vessels			P value
		Single vessel		Multivessel
Total	571	342 (59.9)		229 (40.1)	-
Culprit vessel
Left anterior descending artery	361 (63.2)	246 (71.9)	115 (50.2)		< 0.001
Right coronary artery	152 (26.6)	73 (21.3)	79 (34.5)
Circumflex artery	47 (8.2)	18 (5.3)	29 (12.7)
Posterior descending artery	6 (1.1)	3 (0.9)	3 (1.3)
Left main	5 (0.9)	2 (0.6)	3 (1.3)
Pre-procedure TIMI flow grade
TIMI - 0	321 (56.2)	185 (54.1)	136 (59.4)		0.066
TIMI - 1	58 (10.2)	38 (11.1)	20 (8.7)
TIMI - 2	111 (19.4)	61 (17.8)	50 (21.8)
TIMI - 3	81 (14.2)	58 (17)	23 (10)
Lesion complexity
Non-high/non-C lesion	325 (56.9)	208 (60.8)	117 (51.1)		0.021
High/C lesion	246 (43.1)	134 (39.2)	112 (48.9)
Thrombus presence
No	102 (17.9)	58 (17)	44 (19.2)		0.491
Yes	469 (82.1)	284 (83)	185 (80.8)
Bifurcation lesion
No	427 (74.8)	254 (74.3)	173 (75.5)		0.731
Yes	144 (25.2)	88 (25.7)	56 (24.5)

TIMI: Thrombolysis in myocardial infarction.

Table 3 Post-procedure outcomes stratified by number of vessels involved, n (%)

Characteristics	Total	Involved vessels		P value
		Single vessel	Multivessel
Total	571	342 (59.9)	229 (40.1)	-
Contrast volume (mL)	135.65 ± 44.28	134.3 ± 42.97	137.66 ± 46.18	0.375
Fluro time (min)	13.2 ± 6.69	12.83 ± 6.53	13.75 ± 6.91	0.107
Number of stents deployed	1.09 ± 0.66	1.01 ± 0.44	1.21 ± 0.87	< 0.001
Post-procedure TIMI flow grade
TIMI - 0	3 (0.5)	2 (0.6)	1 (0.4)	0.426
TIMI - 1	3 (0.5)	2 (0.6)	1 (0.4)
TIMI - 2	9 (1.6)	3 (0.9)	6 (2.6)
TIMI - 3	556 (97.4)	335 (98)	221 (96.5)
Post-procedure in-hospital outcomes
Composite adverse events	11 (1.9)	6 (1.8)	5 (2.2)	0.715
Re-infarction	3 (0.5)	3 (0.9)	0 (0)	0.155
Cardiogenic shock	2 (0.4)	0 (0)	2 (0.9)	0.083
Heart failure	2 (0.4)	0 (0)	2 (0.9)	0.083
Dialysis	1 (0.2)	0 (0)	1 (0.4)	0.221
Mortality	7 (1.2)	3 (0.9)	4 (1.7)	0.355

TIMI: Thrombolysis in myocardial infarction.