Endothelin-1 activation in pediatric patients undergoing surgical coarctation of the aorta repair

Figure 1 Serum endothelin-1 concentration. A: Pre-operative ET-1 concentration by age group; B: Comparison between pre-operative and post-operative levels for each age group. ^a,cP < 0.05. Scale bars represent standard deviation. ET-1: Endothelin-1.

Figure 2 Pre-Operative Endothelin-1 as a predictor. A: Correlation between pre-operative ET-1 concentration and post-operative RWT in the subset cohort of neonatal patients; B: Correlation between pre-operative ET-1 concentration and change in level from pre-operative to post-operative sample in the full cohort of patients. Points represent individual patients. ET-1: Endothelin-1; RWT: Relative wall thickness.