Copyright
©The Author(s) 2015.
Figure 1 Chemical structure of flecainide acetate.
Figure 2 Mechanism of flecainide action during atrial fibrillation by inhibition of Na+ channels which reduces intracellular Ca2+ accumulation and reduces oxidative stress and mitochondrial dysfunction.
AF; Atrial fibrillation; INa: Fast inward Na+ current; ROS: Reactive oxygen species; NFκB: Nuclear factor kappa β; ATP: Adenosine triphosphate.
- Citation: Andrikopoulos GK, Pastromas S, Tzeis S. Flecainide: Current status and perspectives in arrhythmia management. World J Cardiol 2015; 7(2): 76-85
- URL: https://www.wjgnet.com/1949-8462/full/v7/i2/76.htm
- DOI: https://dx.doi.org/10.4330/wjc.v7.i2.76