Eosinophilic myocarditis due to parasitic infection: A case-based minireview

Figure 1 Coronary angiography and cardiac magnetic resonance imaging findings in a patient with suspected myocarditis. A and B: Coronary angiography reveals normal coronary anatomy with no evidence of luminal stenosis, effectively excluding obstructive coronary artery disease; C and D: Cardiac magnetic resonance imaging demonstrates focal myocardial injury indicated by arrows, characterized by increased signal intensity on T2-weighted imaging (edema) and late gadolinium enhancement in a subepicardial distribution of the lateral wall, consistent with acute myocarditis.

Figure 2 Eosinophilic activation and myocardial infiltration in the context of parasitic infection. A: Bone marrow smear from the patient reveals a markedly increased number of eosinophils, as demonstrated on the peripheral blood film, suggesting eosinophilic hyperplasia; B: Schematic illustration of the proposed pathophysiological mechanism: Parasitic infection triggers immune activation, leading to eosinophil proliferation and activation. Activated eosinophils subsequently infiltrate the myocardium, contributing to tissue inflammation and injury.

Figure 3  Timeline of clinical presentation, diagnostic workup, treatment, and follow-up in the reported case.