Copyright
©The Author(s) 2022.
World J Cardiol. Jun 26, 2022; 14(6): 329-342
Published online Jun 26, 2022. doi: 10.4330/wjc.v14.i6.329
Published online Jun 26, 2022. doi: 10.4330/wjc.v14.i6.329
Figure 1 Complementary mechanism of action of SGLT-2 inhibitor and GLP-1 receptor agonist dual therapy.
Figure 2 PRISMA flow diagram for randomized controlled trials chosen for meta-analysis.
RCT: Randomized controlled trial.
Figure 3 Three-point major adverse cardiovascular event outcome with GLP-1 receptor agonist plus SGLT-2 inhibitor dual therapy or GLP-1 receptor agonists or SGLT-2 inhibitors vs placebo: A meta-analysis of five cardiovascular outcome trials.
Figure 4 Heart failure hospitalization outcome with GLP-1 receptor agonist plus SGLT-2 inhibitor dual therapy or GLP-1 receptor agonists or SGLT-2 inhibitors vs placebo: A meta-analysis of two cardiovascular outcome trials.
Figure 5 Renal outcome with GLP-1 receptor agonist plus SGLT-2 inhibitor dual therapy or GLP-1 receptor agonists or SGLT-2 inhibitors vs placebo: A meta-analysis of two cardiovascular outcome trials.
- Citation: Singh AK, Singh R. Metabolic and cardiovascular benefits with combination therapy of SGLT-2 inhibitors and GLP-1 receptor agonists in type 2 diabetes. World J Cardiol 2022; 14(6): 329-342
- URL: https://www.wjgnet.com/1949-8462/full/v14/i6/329.htm
- DOI: https://dx.doi.org/10.4330/wjc.v14.i6.329