BRIEF ARTICLE
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World J Cardiol. Feb 26, 2011; 3(2): 48-53
Published online Feb 26, 2011. doi: 10.4330/wjc.v3.i2.48
Global left ventricular performance in non-diabetic non-hypertensive metabolic syndrome adults
Dalia Ibrahiem, Gamela Nasr, Hamdy Sliem
Hamdy Sliem, Department of Internal Medicine, Faculty of Medicine, Suez Canal University, 41522 Ismailia, Egypt
Gamela Nasr, Department of Cardiology, Suez Canal University, 41522 Ismailia, Egypt
Dalia Ibrahiem, Department of physiology, Suez Canal University, 41522 Ismailia, Egypt
Author contributions: Sliem H enrolled metabolic patients in the study and wrote the article; Nasr G performed the echocardiographic evaluations; Ibrahiem D shared in echocardiographic evaluation, collected the laboratory data; all authors made substantial contributions to the conception and design of the study; revised the article, provided statistical analysis and interpretation of data.
Correspondence to: Hamdy Sliem, Assistant Professor, Department of Internal Medicine, Faculty of Medicine, Suez Canal University, 41522 Ismailia, Egypt. hamdy.sliem@yahoo.com
Telephone: +20-2-27549755 Fax: +20-64-3208543
Received: August 20, 2010
Revised: October 10, 2010
Accepted: October 16, 2010
Published online: February 26, 2011
Abstract

AIM: To evaluate the left ventricular structure and function in isolated metabolic syndrome.

METHODS: One hundred and fifty six consecutive adults with metabolic syndrome were enrolled in the study. Fifty nine had isolated metabolic syndrome (group A) and 97 had metabolic syndrome with hypertension and/or diabetes (group B). There was a control group of 34 healthy adults. In addition to classic echocardiographic assessment of myocardial structural and functional changes, the Tei index was used to evaluate global left ventricular performance.

RESULTS: There were no statistically significant differences between group A and controls in all parameters of left ventricular structural, systolic, and diastolic function except global myocardial performance (Tei index). On the other hand, significant differences were observed between group B and the control group in most of the parameters of left ventricular structural and global performance.

CONCLUSION: The early identification of isolated metabolic syndrome in non-diabetic, non-hypertensive adults may be an indication that aggressive preventive measures should not be postponed until overt obesity, hypertension or diabetes mellitus has developed.

Keywords: Metabolic syndrome; Tei-index; Heart function tests