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For: Chaudhary R, Garg J, Shah N, Sumner A. PCSK9 inhibitors: A new era of lipid lowering therapy. World J Cardiol 2017; 9(2): 76-91 [PMID: 28289523 DOI: 10.4330/wjc.v9.i2.76]
URL: https://www.wjgnet.com/1949-8462/full/v9/i2/76.htm
Number Citing Articles
1
Rahayu Zulkapli, Suhaila Abd Muid, Seok Mui Wang, Hapizah Nawawi. PCSK9 Inhibitors Reduce PCSK9 and Early Atherogenic Biomarkers in Stimulated Human Coronary Artery Endothelial CellsInternational Journal of Molecular Sciences 2023; 24(6): 5098 doi: 10.3390/ijms24065098
2
Willemijn A. M. Schonck, Erik S. G. Stroes, G. Kees Hovingh, Laurens F. Reeskamp. Long-Term Efficacy and Tolerability of PCSK9 Targeted Therapy: A Review of the LiteratureDrugs 2024; 84(2): 165 doi: 10.1007/s40265-024-01995-9
3
Bhawneet Chadha, William H. Frishman. Review of the Protective Effects of Statins on CognitionCardiology in Review 2021; 29(6): 328 doi: 10.1097/CRD.0000000000000359
4
Manasvi Gupta, Ramyashree Tummala, Raktim K. Ghosh, Colin Blumenthal, Karan Philip, Dhrubajyoti Bandyopadhyay, Hector Ventura, Prakash Deedwania. An update on pharmacotherapies in diabetic dyslipidemiaProgress in Cardiovascular Diseases 2019; 62(4): 334 doi: 10.1016/j.pcad.2019.07.006
5
Yoon kyung Chang, Tae-Jin Song. Management of Dyslipidemia after StrokeJournal of the Korean Neurological Association 2022; 40(3): 217 doi: 10.17340/jkna.2022.3.1
6
Rajeev Chawla, SV Madhu, BM Makkar, Sujoy Ghosh, Banshi Saboo, Sanjay Kalra. RSSDI-ESI clinical practice recommendations for the management of type 2 diabetes mellitus 2020Indian Journal of Endocrinology and Metabolism 2020; 24(1): 1 doi: 10.4103/ijem.IJEM_225_20
7
Daniela Grejtakova, Iveta Boronova, Jarmila Bernasovska, Stefano Bellosta. PCSK9 and Lipid Metabolism: Genetic Variants, Current Therapies, and Cardiovascular OutcomesCardiovascular Drugs and Therapy 2024;  doi: 10.1007/s10557-024-07599-5
8
Anastasia V. Poznyak, Dwaipayan Bharadwaj, Gauri Prasad, Andrey V. Grechko, Margarita A. Sazonova, Alexander N. Orekhov. Anti-Inflammatory Therapy for Atherosclerosis: Focusing on CytokinesInternational Journal of Molecular Sciences 2021; 22(13): 7061 doi: 10.3390/ijms22137061
9
Roshni S. Patel, Emily M. Scopelliti, Oludamilola Olugbile. The Role of PCSK9 Inhibitors in the Treatment of HypercholesterolemiaAnnals of Pharmacotherapy 2018; 52(10): 1000 doi: 10.1177/1060028018771670
10
Hanan B Albackr, Khalid Al Waili, Wael Almahmeed, Mohammad Al Jarallah, Mohammad I Amin, Khalid Alrasadi, Mohammed A. Batais, Turky H. Almigbal, Ali Youssef, Mohammad Alghamdi, Mohammad Al Shehri, Islam Ahmad, Riham A. ElToukhy, Naji Kholaif, Abdulhalim J. Kinsara, Manal Al-Kindi, Nooshin Barzargani, Magdy Hassan, Shamsa Al Suwaidi, Rajesh Rajan, Hani Altaradi, Khalid F Alhabib. The Gulf Achievement of Cholesterol Targets in Out-Patients Study (GULF ACTION): Design, Rationale, and Preliminary ResultsCurrent Vascular Pharmacology 2023; 21(4): 285 doi: 10.2174/1570161121666230710145604
11
Enrique Gallego-Colon, Aner Daum, Chaim Yosefy. Statins and PCSK9 inhibitors: A new lipid-lowering therapyEuropean Journal of Pharmacology 2020; 878: 173114 doi: 10.1016/j.ejphar.2020.173114
12
Meghan L. Good, Parisa Malekzadeh, Samantha M. Ruff, Shreya Gupta, Amy Copeland, Karel Pacak, Naris Nilubol, Electron Kebebew, Dhaval Patel. Surgical Resection of Pheochromocytomas and Paragangliomas is Associated with Lower Cholesterol LevelsWorld Journal of Surgery 2020; 44(2): 552 doi: 10.1007/s00268-019-05175-9
13
Kitty Pham, Anwar Mulugeta, Amanda Lumsden, Elina Hyppӧnen. Genetically instrumented LDL‐cholesterol lowering and multiple disease outcomes: A Mendelian randomization phenome‐wide association study in the UK BiobankBritish Journal of Clinical Pharmacology 2023; 89(10): 2992 doi: 10.1111/bcp.15793
14
扬 刘. Application of PCSK9 Inhibitors in Lipid Metabolism and ArteriosclerosisAdvances in Clinical Medicine 2023; 13(08): 12430 doi: 10.12677/ACM.2023.1381742
15
Barak Zafrir, Aya Egbaria, Nili Stein, Avishay Elis, Walid Saliba. PCSK9 inhibition in clinical practice: Treatment patterns and attainment of lipid goals in a large health maintenance organizationJournal of Clinical Lipidology 2021; 15(1): 202 doi: 10.1016/j.jacl.2020.11.004
16
Isis Paez, Yalena Prado, Pía Loren, Carmen G. Ubilla, Nelia Rodríguez, Luis A. Salazar. Cholesterol-Related lncRNAs as Response Predictors of Atorvastatin Treatment in Chilean Hypercholesterolemic Patients: A Pilot StudyBiomedicines 2023; 11(3): 742 doi: 10.3390/biomedicines11030742
17
Jay Shendure, Gregory M. Findlay, Matthew W. Snyder. Genomic Medicine–Progress, Pitfalls, and PromiseCell 2019; 177(1): 45 doi: 10.1016/j.cell.2019.02.003
18
Natalie C. Ward, Michael M. Page, Gerald F. Watts. PCSK9 inhibition 2018: riding a new wave of coronary preventionClinical Science 2019; 133(2): 205 doi: 10.1042/CS20171300
19
Katrine Bjune, Lene Wierød, Soheil Naderi. Triciribine increases LDLR expression and LDL uptake through stabilization of LDLR mRNAScientific Reports 2018; 8(1) doi: 10.1038/s41598-018-34237-6
20
Allison B. Reiss, Neal Shah, Dalia Muhieddine, Juan Zhen, Jennifer Yudkevich, Lora J. Kasselman, Joshua DeLeon. PCSK9 in cholesterol metabolism: from bench to bedsideClinical Science 2018; 132(11): 1135 doi: 10.1042/CS20180190
21
Charles A. German, Michael D. Shapiro. Small Interfering RNA Therapeutic Inclisiran: A New Approach to Targeting PCSK9BioDrugs 2020; 34(1): 1 doi: 10.1007/s40259-019-00399-6
22
Manik Chhabra, Kota Vidyasagar, Sai Krishna Gudi, Jatin Sharma, Rishabh Sharma, Muhammed Rashid, Jie V. Zhao. Efficacy and safety of saroglitazar for the management of dyslipidemia: A systematic review and meta-analysis of interventional studiesPLOS ONE 2022; 17(7): e0269531 doi: 10.1371/journal.pone.0269531
23
Dongqi Zhu, Hongyu Qin, Xiaojing Wang, Yuping Jia, Xuejian Wang, Lei Zhang. Discovery of [5,5′‐bibenzo[d][1,3]dioxol]‐6‐substituted amine derivatives as potent proprotein convertase subtilisin/kexin type 9 inhibitorsChemical Biology & Drug Design 2023; 102(1): 153 doi: 10.1111/cbdd.14264
24
Michael S. Saporito. Remington2021; : 663 doi: 10.1016/B978-0-12-820007-0.00034-9
25
Daniela T. Fuller, Andrew T. Grainger, Ani Manichaikul, Weibin Shi. Genetic linkage of oxidative stress with cardiometabolic traits in an intercross derived from hyperlipidemic mouse strainsAtherosclerosis 2020; 293: 1 doi: 10.1016/j.atherosclerosis.2019.11.034
26
Martina Bartolomei, Carlotta Bollati, Jianqiang Li, Anna Arnoldi, Carmen Lammi. Assessment of the Cholesterol-Lowering Effect of MOMAST®: Biochemical and Cellular StudiesNutrients 2022; 14(3): 493 doi: 10.3390/nu14030493
27
Rida Zainab, Afshan Kaleem, Michał B. Ponczek, Roheena Abdullah, Mehwish Iqtedar, Daniel C. Hoessli, Emilio Gallicchio. Finding inhibitors for PCSK9 using computational methodsPLOS ONE 2021; 16(8): e0255523 doi: 10.1371/journal.pone.0255523
28
Natalie C. Ward, Gerald F. Watts. PCSK9 monoclonal antibody on a knife-edge: An article of faith in FH?Journal of Clinical Lipidology 2018; 12(4): 844 doi: 10.1016/j.jacl.2018.05.015
29
Zohaib Iqbal, Shaishav Dhage, Jamal Basheer Mohamad, Alaa Abdel-Razik, Rachelle Donn, Rayaz Malik, Jan Hoong Ho, Yifen Liu, Safwaan Adam, Basil Isa, Claudia Stefanutti, Handrean Soran. Efficacy and safety of PCSK9 monoclonal antibodiesExpert Opinion on Drug Safety 2019; 18(12): 1191 doi: 10.1080/14740338.2019.1681395
30
Stephen Daniels, Sonia Caprio, Umesh Chaudhari, Garen Manvelian, Marie T. Baccara-Dinet, Aurelie Brunet, Michel Scemama, Virginie Loizeau, Eric Bruckert. PCSK9 inhibition with alirocumab in pediatric patients with heterozygous familial hypercholesterolemia: The ODYSSEY KIDS studyJournal of Clinical Lipidology 2020; 14(3): 322 doi: 10.1016/j.jacl.2020.03.001
31
Małgorzata Bednarska-Makaruk, Agnieszka Ługowska. Cholesterol2022; : 553 doi: 10.1016/B978-0-323-85857-1.00024-9
32
M. I. Voevoda, V. S. Gurevich, M. V. Ezhov, I. V. Sergienko. Inclisiran – a new era in lipid-lowering therapyKardiologiia 2022; 62(6): 57 doi: 10.18087/cardio.2022.6.n2115
33
Levi W. Evans, Blythe Durbin-Johnson, Kristen J. Sutton, Phoebe Yam, Yasmine Y. Bouzid, Eduardo Cervantes, Ellen Bonnel, Charles B. Stephenson, Brian J. Bennett. Specific circulating miRNAs are associated with plasma lipids in a healthy American cohortPhysiological Genomics 2024; 56(7): 492 doi: 10.1152/physiolgenomics.00087.2023
34
Smruti M Besekar, Sangita D Jogdand, Waqar M Naqvi. A Systematic Review of the Randomized Controlled Trials of Gemcabene and Its Therapeutic UsesCureus 2023;  doi: 10.7759/cureus.36811
35
Gabriela Alexandra Solano Peña, Gabriela Fernanda Acurio Armas, Gabriela Alejandra Díaz Teran, Susana Patricia Palacios Serrano, Andrea Carolina Cobo Reyes, Daniel Albino Pullas Taboada, Gissel Katherine Carvajal Chango. Inhibición de PCSK9: una nueva alternativa para reducir el colesterol y prevenir la enfermedad cardiovascular aterosclerosaSalud, Ciencia y Tecnología 2023; 3: 587 doi: 10.56294/saludcyt2023587
36
Yoonkyung Chang, Soojeong Eom, Minjeong Kim, Tae-Jin Song. Medical Management of Dyslipidemia for Secondary Stroke Prevention: Narrative ReviewMedicina 2023; 59(4): 776 doi: 10.3390/medicina59040776
37
Nadir Ali, David M. Diamond, Sarah M. Rice. Ketogenic2023; : 205 doi: 10.1016/B978-0-12-821617-0.00016-4
38
Carmen Lammi, Maria Bellumori, Lorenzo Cecchi, Martina Bartolomei, Carlotta Bollati, Maria Lisa Clodoveo, Filomena Corbo, Anna Arnoldi, Nadia Mulinacci. Extra Virgin Olive Oil Phenol Extracts Exert Hypocholesterolemic Effects through the Modulation of the LDLR Pathway: In Vitro and Cellular Mechanism of Action ElucidationNutrients 2020; 12(6): 1723 doi: 10.3390/nu12061723
39
Chao Luan, Yingxue He, Wen Liu, Yicheng Rong, Jian Gao, Kang Xu, Hui Yu, Yu Hu, Jiaan Zhang, Kun Chen, Wenjie Guo. PCSK9 inhibition interrupts the cross-talk between keratinocytes and macrophages and prevents UVB-induced skin damageJournal of Biological Chemistry 2023; 299(7): 104895 doi: 10.1016/j.jbc.2023.104895
40
Jiali Zhu, Xuemei Zhang, Xiu Chen, Yong Sun, Yaolan Dai, Chang Chen, Tiane Zhang, Zhiyong Yan. Studies on the regulation of lipid metabolism and the mechanism of the aqueous and ethanol extracts of UsneaBiomedicine & Pharmacotherapy 2017; 94: 930 doi: 10.1016/j.biopha.2017.08.012
41
Lin Jiang, Hui Jiang, Sheng Dai, Ying Chen, Youqiang Song, Clara Sze-Man Tang, Shirley Yin-Yu Pang, Shu-Leong Ho, Binbin Wang, Maria-Mercedes Garcia-Barcelo, Paul Kwong-Hang Tam, Stacey S Cherny, Mulin Jun Li, Pak Chung Sham, Miaoxin Li. Deviation from baseline mutation burden provides powerful and robust rare-variants association test for complex diseasesNucleic Acids Research 2022; 50(6): e34 doi: 10.1093/nar/gkab1234
42
Ricardo Fontes-Carvalho, Pedro Marques Silva, Elisabete Rodrigues, Francisco Araújo, Cristina Gavina, Jorge Ferreira, João Morais. Practical guide for the use of PCSK9 inhibitors in PortugalRevista Portuguesa de Cardiologia (English Edition) 2019; 38(6): 391 doi: 10.1016/j.repce.2019.07.004
43
Oluwakemi Ebenezer, Pietro Comoglio, Gane Ka-Shu Wong, Jack A. Tuszynski. Development of Novel siRNA Therapeutics: A Review with a Focus on Inclisiran for the Treatment of HypercholesterolemiaInternational Journal of Molecular Sciences 2023; 24(4): 4019 doi: 10.3390/ijms24044019
44
Shakir Ahamad, Shahnawaz A. Bhat. Recent Update on the Development of PCSK9 Inhibitors for Hypercholesterolemia TreatmentJournal of Medicinal Chemistry 2022; 65(23): 15513 doi: 10.1021/acs.jmedchem.2c01290
45
Stella Talic, Clara Marquina Hernandez, Richard Ofori-Asenso, Danny Liew, Alice Owen, Marjana Petrova, Sean Lybrand, David Thomson, Jenni Ilomaki, Zanfina Ademi, Ella Zomer. Trends in the Utilization of Lipid-Lowering Medications in Australia: An Analysis of National Pharmacy Claims DataCurrent Problems in Cardiology 2022; 47(7): 100880 doi: 10.1016/j.cpcardiol.2021.100880
46
Usama Bin Ghaffar. Determinants of Risk Factors Associated with Aortic Atherosclerosis: A Quantitative Study in Forensic AutopsiesBiosciences Biotechnology Research Asia 2024; 21(1): 157 doi: 10.13005/bbra/3211
47
Rupesh Maurya, Gargi Bhattacharjee, Nisarg Gohil, Khushal Khambhati, Shreya Shakhreliya, Aaradhya Bhatnagar, Priyanka Singh, Suresh Ramakrishna, Vijai Singh. Receptor Endocytosis and Signalling in Health and Disease - Part AProgress in Molecular Biology and Translational Science 2023; 194: 333 doi: 10.1016/bs.pmbts.2022.09.010
48
Marion Laudette, Malin Lindbom, Muhammad Arif, Mathieu Cinato, Mario Ruiz, Stephen Doran, Azra Miljanovic, Mikael Rutberg, Linda Andersson, Martina Klevstig, Marcus Henricsson, Per-Olof Bergh, Entela Bollano, Nay Aung, J Gustav Smith, Marc Pilon, Tuulia Hyötyläinen, Matej Orešič, Rosie Perkins, Adil Mardinoglu, Malin C Levin, Jan Borén. Cardiomyocyte-specific PCSK9 deficiency compromises mitochondrial bioenergetics and heart functionCardiovascular Research 2023; 119(7): 1537 doi: 10.1093/cvr/cvad041
49
Camille B. Carroll, Richard K.H. Wyse. Simvastatin as a Potential Disease-Modifying Therapy for Patients with Parkinson’s Disease: Rationale for Clinical Trial, and Current ProgressJournal of Parkinson's Disease 2017; 7(4): 545 doi: 10.3233/JPD-171203
50
Hideyuki Torikai, Mei-Hua Chen, Li Jin, Jiang He, John F. Angle, Weibin Shi. Atherogenesis in Apoe−/− and Ldlr−/− Mice with a Genetically Resistant BackgroundCells 2023; 12(9): 1255 doi: 10.3390/cells12091255
51
Benjamin J. Tombling, Conan K. Wang, David J. Craik. EGF‐like and Other Disulfide‐rich Microdomains as Therapeutic ScaffoldsAngewandte Chemie International Edition 2020; 59(28): 11218 doi: 10.1002/anie.201913809
52
Mohammad Alkhalil. Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibitors, Reality or Dream in Managing Patients with Cardiovascular DiseaseCurrent Drug Metabolism 2019; 20(1): 72 doi: 10.2174/1389200219666180816141827
53
Mohamed Toufic El Hussein, Aditi Sharma, Komal Parmar, Krupa Shelat. Pharmacotherapeutics for dyslipidemia managementThe Nurse Practitioner 2023; 48(6): 36 doi: 10.1097/01.NPR.0000000000000059
54
Esther Torres, Marian Goicoechea, Andrés Hernández, María L. Rodríguez Ferrero, Ana García, Nicolás Macías, Fernando Anaya. Efficacy of Evolocumab vs low‐density lipoprotein cholesterol apheresis in patients with familial hypercholesterolemia and high cardiovascular risk (EVOLAFER01)Journal of Clinical Apheresis 2020; 35(1): 9 doi: 10.1002/jca.21752
55
Donatella Zodda, Rosario Giammona, Silvia Schifilliti. Treatment Strategy for Dyslipidemia in Cardiovascular Disease Prevention: Focus on Old and New DrugsPharmacy 2018; 6(1): 10 doi: 10.3390/pharmacy6010010
56
Tingting Yuan, Yi Zhong, Yingge Wang, Ting Zhang, Rui Lu, Minya Zhou, Yaoyao Lu, Kunning Yan, Yajie Chen, Zhehui Hu, Jingyan Liang, Jianglin Fan, Yong Cheng. Generation of hyperlipidemic rabbit models using multiple sgRNAs targeted CRISPR/Cas9 gene editing systemLipids in Health and Disease 2019; 18(1) doi: 10.1186/s12944-019-1013-8
57
Rafael Campo. Estudios clínicos con inhibidores de la PCSK9Revista Colombiana de Cardiología 2017; 24: 13 doi: 10.1016/j.rccar.2017.08.019
58
Carmen Lammi, Carlotta Bollati, Davide Lecca, Maria Pia Abbracchio, Anna Arnoldi. Lupin Peptide T9 (GQEQSHQDEGVIVR) Modulates the Mutant PCSK9D374Y Pathway: in vitro Characterization of its Dual Hypocholesterolemic BehaviorNutrients 2019; 11(7): 1665 doi: 10.3390/nu11071665
59
Nivas Shyamala, Kishore Kumar Gundapaneni, Rajesh Kumar Galimudi, Mohini Aiyengar Tupurani, Chiranjeevi Padala, Kaushik Puranam, Keerthi Kupsal, Ramanjaneyulu Kummari, Srilatha Reddy Gantala, Krishna Reddy Nallamala, Sanjib K. Sahu, Surekha Rani Hanumanth. PCSK9 genetic (rs11591147) and epigenetic (DNA methylation) modifications associated with PCSK9 expression and serum proteins in CAD patientsThe Journal of Gene Medicine 2021; 23(8) doi: 10.1002/jgm.3346
60
Elena Domingo, Patrice Marques, Vera Francisco, Laura Piqueras, Maria-Jesus Sanz. Targeting systemic inflammation in metabolic disorders. A therapeutic candidate for the prevention of cardiovascular diseases?Pharmacological Research 2024; 200: 107058 doi: 10.1016/j.phrs.2024.107058
61
Sonia Singh, Manas Kumar Jha. Review on PCSK9: A Pertinent Therapeutic Target in Cardiovascular DiseaseCurrent Bioactive Compounds 2024; 20(1) doi: 10.2174/0115734072270060230921093431
62
Olivia M. Kim, Tatyana K. Givens, Emily G. Tang, Jennifer J. Schimmer, Tanya Ramsey, Kayla Boyd, Thomas Delate. Real-World Outcomes of Proprotein Convertase Subtilisin Kexin-9 Inhibitor UseJournal of Cardiovascular Pharmacology 2023; 81(5): 339 doi: 10.1097/FJC.0000000000001404
63
Gbolahan Olatunji, Emmanuel Kokori, Ismaila Ajayi Yusuf, Olumide Akinmoju, Emmanuel Egbunu, Ifeanyichukwu Muogbo, Kaleb Lema, Sai Gutham Kanagala, Samuel Owolabi, Muili Abdulbasit, Nicholas Aderinto. Inclisiran siRNA technology in the management of dyslipidemia: A narrative review of clinical trialsCurrent Problems in Cardiology 2024; 49(4): 102419 doi: 10.1016/j.cpcardiol.2024.102419
64
Alisha Aman, Eric A. W. Slob, Joey Ward, Breda Cullen, Nicholas Graham, Donald M. Lyall, Naveed Sattar, Rona J. Strawbridge, Toni-Kim Clarke. Investigating the potential impact of PCSK9-inhibitors on mood disorders using eQTL-based Mendelian randomizationPLOS ONE 2022; 17(12): e0279381 doi: 10.1371/journal.pone.0279381
65
Joyson J. Karakunnel, Nam Bui, Latha Palaniappan, Keith T. Schmidt, Kenneth W. Mahaffey, Briggs Morrison, William D. Figg, Shivaani Kummar. Reviewing the role of healthy volunteer studies in drug developmentJournal of Translational Medicine 2018; 16(1) doi: 10.1186/s12967-018-1710-5
66
V. V. Ryabov, Ya. V. Alekseeva, A. E. Gombozhapova, Ya. V. Sokolova, R. S. Karpov. Atherosclerosis. Macrophages. Viral infectionsThe Siberian Journal of Clinical and Experimental Medicine 2021; 36(2): 14 doi: 10.29001/2073-8552-2021-36-2-14-22
67
Natalie C. Ward, Gerald F. Watts. Therapeutic LipidologyContemporary Cardiology 2021; : 615 doi: 10.1007/978-3-030-56514-5_33
68
AjayK Shukla, Rekha Mehani. Safety and efficacy of alirocumab: A meta analysis of 12 randomized controlled trialsJournal of Family Medicine and Primary Care 2019; 8(7): 2249 doi: 10.4103/jfmpc.jfmpc_406_19
69
Benjamin J. Tombling, Conan K. Wang, David J. Craik. EGF‐artige und andere disulfidreiche Mikrodomänen als therapeutische MolekülgerüsteAngewandte Chemie 2020; 132(28): 11314 doi: 10.1002/ange.201913809
70
Rajinderpal Singh, Sohbat Kaur Chandi, Seerat Sran, Smriti K Aulakh, Gurkamal Singh Nijjar, Kanwarmandeep Singh, Sumerjit Singh, FNU Tanvir, Yasmeen Kaur, Ajay Pal Singh Sandhu. Emerging Therapeutic Strategies in Cardiovascular DiseasesCureus 2024;  doi: 10.7759/cureus.64388
71
Niki Katsiki, Dimitri P Mikhailidis, Maciej Banach. Lipid-lowering agents for concurrent cardiovascular and chronic kidney diseaseExpert Opinion on Pharmacotherapy 2019; 20(16): 2007 doi: 10.1080/14656566.2019.1649394
72
Michele Scognamiglio, Dario Costa, Antonio Sorriento, Claudio Napoli. Current Drugs and Nutraceuticals for the Treatment of Patients with DyslipidemiasCurrent Pharmaceutical Design 2019; 25(1): 85 doi: 10.2174/1381612825666190130101108
73
Dean L. Kellogg, Susan Fisher-Hoch, Joseph B. McCormick, Anand Prasad. Searching for the Genetic Determinants of Peripheral Arterial DiseaseCardiology in Review 2019; 27(3): 145 doi: 10.1097/CRD.0000000000000231
74
Dieter K. Lam, Patricia R. Feliciano, Amena Arif, Tanggis Bohnuud, Thomas P. Fernandez, Jason M. Gehrke, Phil Grayson, Kin D. Lee, Manuel A. Ortega, Courtney Sawyer, Noah D. Schwaegerle, Leila Peraro, Lauren Young, Seung-Joo Lee, Giuseppe Ciaramella, Nicole M. Gaudelli. Improved cytosine base editors generated from TadA variantsNature Biotechnology 2023; 41(5): 686 doi: 10.1038/s41587-022-01611-9
75
PRIYANKA VENUNGOPAL, KARTHIKEYAN BALAKRISHNAN, DAMAL KANDADAI SRIRAM, MELVIN GEORGE. INCLISIRAN (LEQVIO): A FIRST-IN-CLASS SMALL INTERFERING RNA THERAPEUTIC DRUG APPROVED BY FDA FOR TREATING PRIMARY HYPERCHOLESTEROLEMIA OR DYSLIPIDEMIAAsian Journal of Pharmaceutical and Clinical Research 2022; : 42 doi: 10.22159/ajpcr.2022.v15i12.46054
76
X. Pintó, I. Sarasa. Nuevas perspectivas en el tratamiento de la hipercolesterolemia desde la disponibilidad de los inhibidores de la proteína PCSK9Hipertensión y Riesgo Vascular 2019; 36(4): 213 doi: 10.1016/j.hipert.2019.05.005
77
Junying Miao, Xiaoling Zang, Xiaoling Cui, Jun Zhang. Autophagy: Biology and DiseasesAdvances in Experimental Medicine and Biology 2020; 1207: 237 doi: 10.1007/978-981-15-4272-5_18
78
Roberto Garcia, Jaime Burkle. New and Future Parenteral Therapies for the Management of Lipid DisordersArchives of Medical Research 2018; 49(8): 538 doi: 10.1016/j.arcmed.2019.01.001
79
Alexander D. Mazura, Claus U. Pietrzik. Endocrine Regulation of Microvascular Receptor—Mediated Transcytosis and Its Therapeutic Opportunities: Insights by PCSK9—Mediated RegulationPharmaceutics 2023; 15(4): 1268 doi: 10.3390/pharmaceutics15041268
80
Chanisa Thonusin, Nattayaporn Apaijai, Thidarat Jaiwongkam, Sasiwan Kerdphoo, Busarin Arunsak, Patchareeya Amput, Siripong Palee, Wasana Pratchayasakul, Nipon Chattipakorn, Siriporn C. Chattipakorn. The comparative effects of high dose atorvastatin and proprotein convertase subtilisin/kexin type 9 inhibitor on the mitochondria of oxidative muscle fibers in obese-insulin resistant female ratsToxicology and Applied Pharmacology 2019; 382: 114741 doi: 10.1016/j.taap.2019.114741
81
Nikolaos Velidakis, Panagiotis Stachteas, Evangelia Gkougkoudi, Christodoulos Papadopoulos, Nikolaos P. E. Kadoglou. Classical and Novel Lipid-Lowering Therapies for Diabetic Patients with Established Coronary Artery Disease or High Risk of Coronary Artery Disease—A Narrative Clinical ReviewPharmaceuticals 2024; 17(5): 568 doi: 10.3390/ph17050568
82
Veronika A. Myasoedova, Alessio L. Ravani, Beatrice Frigerio, Vincenza Valerio, Donato Moschetta, Paola Songia, Paolo Poggio. Novel pharmacological targets for calcific aortic valve disease: Prevention and treatmentsPharmacological Research 2018; 136: 74 doi: 10.1016/j.phrs.2018.08.020
83
Philip Branigan, Y. V Duong, Ammar Y Abdulfattah, Jacob Sabu, Mary Mallappallil, Sabu John. Towards Optimal Cardiovascular Health: A Comprehensive Review of Preventive StrategiesCureus 2024;  doi: 10.7759/cureus.60877
84
Pilar Hoyos, Vittorio Pace, Andrés R. Alcántara. Biocatalyzed Synthesis of Statins: A Sustainable Strategy for the Preparation of Valuable DrugsCatalysts 2019; 9(3): 260 doi: 10.3390/catal9030260
85
Xiaoming Jia, Mahmoud Al Rifai, Anum Saeed, Christie M Ballantyne, Salim S Virani. PCSK9 Inhibitors in the Management of Cardiovascular Risk: A Practical GuidanceVascular Health and Risk Management 2022; : 555 doi: 10.2147/VHRM.S275739
86
Hamideh Amirfakhryan. Vaccination against atherosclerosis: An overviewHellenic Journal of Cardiology 2020; 61(2): 78 doi: 10.1016/j.hjc.2019.07.003
87
Isabella Giacomini, Federico Gianfanti, Maria Andrea Desbats, Genny Orso, Massimiliano Berretta, Tommaso Prayer-Galetti, Eugenio Ragazzi, Veronica Cocetta. Cholesterol Metabolic Reprogramming in Cancer and Its Pharmacological Modulation as Therapeutic StrategyFrontiers in Oncology 2021; 11 doi: 10.3389/fonc.2021.682911
88
Velimir Altabas, Lora Stanka Kirigin Biloš. The Role of Endothelial Progenitor Cells in Atherosclerosis and Impact of Anti-Lipemic Treatments on Endothelial RepairInternational Journal of Molecular Sciences 2022; 23(5): 2663 doi: 10.3390/ijms23052663
89
Michael A. Hicks, Claire Y.C. Hou, Arya Iranmehr, Krisztina Marosi, Ewen Kirkness. Target discovery using biobanks and human geneticsDrug Discovery Today 2020; 25(2): 438 doi: 10.1016/j.drudis.2019.09.014
90
James Milner, Andreia Cunha, Carlota Gamboa-Cruz, Julie Reis, Márcia Campos, Natália António. Recent major advances in cardiovascular pharmacotherapyEuropean Journal of Clinical Pharmacology 2018; 74(7): 853 doi: 10.1007/s00228-018-2453-1
91
Yajnavalka Banerjee, Anca Pantea Stoian, Arrigo Francesco Giuseppe Cicero, Federica Fogacci, Dragana Nikolic, Alexandros Sachinidis, Ali A. Rizvi, Andrej Janez, Manfredi Rizzo. Inclisiran: a small interfering RNA strategy targeting PCSK9 to treat hypercholesterolemiaExpert Opinion on Drug Safety 2022; 21(1): 9 doi: 10.1080/14740338.2022.1988568
92
Aisha Siddiq A, Asha Martin. Crocetin exerts hypocholesterolemic effect by inducing LDLR and inhibiting PCSK9 and Sortilin in HepG2 cellsNutrition Research 2022; 98: 41 doi: 10.1016/j.nutres.2021.08.005
93
Marko Kumric, Hrvoje Urlic, Josko Bozic, Marino Vilovic, Tina Ticinovic Kurir, Duska Glavas, Dino Miric, Jaksa Zanchi, Anteo Bradaric-Slujo, Mislav Lozo, Josip A. Borovac. Emerging Therapies for the Treatment of Atherosclerotic Cardiovascular Disease: From Bench to BedsideInternational Journal of Molecular Sciences 2023; 24(9): 8062 doi: 10.3390/ijms24098062
94
Amy Elizabeth Morgan, Mark Tomás Mc Auley. Cholesterol Homeostasis: An In Silico Investigation into How Aging Disrupts Its Key Hepatic Regulatory MechanismsBiology 2020; 9(10): 314 doi: 10.3390/biology9100314
95
Henry T. Greely. Human Germline Genome Editing: An AssessmentThe CRISPR Journal 2019; 2(5): 253 doi: 10.1089/crispr.2019.0038
96
Truong Phuong Kim, Lao Thuan Duc, Huyen Le Thuy Ai. The Major Molecular Causes of Familial HypercholesterolemiaAsian Journal of Pharmaceutical Research and Health Care 2018; 10(2): 60 doi: 10.18311/ajprhc/2018/20031
97
Penelope Poppy Janpen Sucharitkul, Keely Louise Jones, David Julian Ashbridge Scott, Marc Aaron Bailey. Lipid Optimization in Lower Extremity Peripheral Arterial DiseaseAnnals of Vascular Surgery 2021; 76: 542 doi: 10.1016/j.avsg.2021.03.055
98
Danial Khayatan, Kimia Zare, Maryam Khanahmadi, Saeideh Momtaz, Alexandra E. Butler, Tannaz Jamialahmadi, Wael Almahmeed, Amir Hossein Abdolghaffari, Amirhossein Sahebkar. The role of natural products as PCSK9 modulators: A reviewPhytotherapy Research 2024;  doi: 10.1002/ptr.8260
99
Vesna Vucic, Romana Masnikosa. Reference Module in Food Science2017;  doi: 10.1016/B978-0-08-100596-5.21339-5
100
Ching-Hui Sia, Oliver Simon, Poay-Huan Loh, Kian Keong Poh. Atherosclerotic cardiovascular disease landscape in SingaporeFrontiers in Cardiovascular Medicine 2024; 11 doi: 10.3389/fcvm.2024.1342698
101
Carmen Lammi, Nadia Mulinacci, Lorenzo Cecchi, Maria Bellumori, Carlotta Bollati, Martina Bartolomei, Carlo Franchini, Maria Lisa Clodoveo, Filomena Corbo, Anna Arnoldi. Virgin Olive Oil Extracts Reduce Oxidative Stress and Modulate Cholesterol Metabolism: Comparison between Oils Obtained with Traditional and Innovative ProcessesAntioxidants 2020; 9(9): 798 doi: 10.3390/antiox9090798
102
Iveta Merćep, Dominik Strikić, Ana Marija Slišković, Željko Reiner. New Therapeutic Approaches in Treatment of Dyslipidaemia—A Narrative ReviewPharmaceuticals 2022; 15(7): 839 doi: 10.3390/ph15070839
103
Poobalan Naidoo, Rashem Mothilal, Dirk Jacobus Blom. Therapeutic Management of Dyslipidemia Patients at Very High Cardiovascular Risk (CARDIO TRACK): Protocol for the Observational Registry StudyJMIR Research Protocols 2018; 7(6): e163 doi: 10.2196/resprot.9248
104
Kerstin Stemmer, Brian Finan, Richard D. DiMarchi, Matthias H. Tschöp, Timo D. Müller. Insights into incretin-based therapies for treatment of diabetic dyslipidemiaAdvanced Drug Delivery Reviews 2020; 159: 34 doi: 10.1016/j.addr.2020.05.008
105
Rabia Shahid, Shaili S Naik, Shivana Ramphall, Swarnima Rijal, Vishakh Prakash, Heba Ekladios, Jiya Mulayamkuzhiyil Saju, Naishal Mandal, Nang I Kham, Pousette Hamid. Neurocognitive Impairment in Cardiovascular Disease Patients Taking Statins Versus Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibitors: A Systematic ReviewCureus 2022;  doi: 10.7759/cureus.30942
106
Anindya Amanda Damayanti, Riana Rahmawati, Amany Taqiyyah Wardhani, Raisa Kamila Putri, Zavia Putri Salsabila. Proceedings of the 3rd International Conference on Cardiovascular Diseases (ICCvD 2021)2023; : 293 doi: 10.2991/978-94-6463-048-0_33
107
Son Min-Gyung, Pisey Pel, Chae-Yeong An, Chan-Woong Park, Sae Hyun Lee, Tae-Jin Yang, Young-Won Chin. Chemical constituents from the roots of Cynanchum wilfordii with PCSK9 secretion inhibitory activitiesPhytochemistry 2024; 226: 114205 doi: 10.1016/j.phytochem.2024.114205
108
Satyavir Yadav, Jitendra Pal Singh Sawhney. Treatment of dyslipidemia in acute coronary syndromeIndian Heart Journal 2024; 76: S51 doi: 10.1016/j.ihj.2024.01.011
109
Ivo P. van de Peppel, Anna Bertolini, Theo H. van Dijk, Albert K. Groen, Johan W. Jonker, Henkjan J. Verkade. Efficient reabsorption of transintestinally excreted cholesterol is a strong determinant for cholesterol disposal in miceJournal of Lipid Research 2019; 60(9): 1562 doi: 10.1194/jlr.M094607
110
Aditi Sharma, Chakshu Sharma, Lalit Sharma, Pranay Wal, Preeti Mishra, Nitin Sachdeva, Shivam Yadav, Celia Vargas De-La Cruz, Sandeep Arora, Vetriselvan Subramaniyan, Ravi Rawat, Tapan Behl, Mukesh Nandave. Targeting the vivid facets of apolipoproteins as a cardiovascular risk factor in rheumatoid arthritisCanadian Journal of Physiology and Pharmacology 2024; 102(5): 305 doi: 10.1139/cjpp-2023-0259
111
Shuo Geng, Yajun Wu, Liwu Li. Immune HomeostasisMethods in Molecular Biology 2024; 2782: 25 doi: 10.1007/978-1-0716-3754-8_2
112
Maureen Sampson, Anna Wolska, Justine Cole, Rafael Zubirán, James D. Otvos, Jeff W. Meeusen, Leslie J. Donato, Allan S. Jaffe, Alan T. Remaley. Accuracy and Clinical Impact of Estimating Low-Density Lipoprotein-Cholesterol at High and Low Levels by Different EquationsBiomedicines 2022; 10(12): 3156 doi: 10.3390/biomedicines10123156
113
Giovanni Ciccarelli, Saverio D’Elia, Michele De Paulis, Paolo Golino, Giovanni Cimmino. Lipid Target in Very High-Risk Cardiovascular Patients: Lesson from PCSK9 Monoclonal AntibodiesDiseases 2018; 6(1): 22 doi: 10.3390/diseases6010022
114
Pratiksha Jamadade, Neh Nupur, Krushna Ch Maharana, Sanjiv Singh. Therapeutic Monoclonal Antibodies for Metabolic Disorders: Major Advancements and Future PerspectivesCurrent Atherosclerosis Reports 2024;  doi: 10.1007/s11883-024-01228-0
115
Yanqiang Zou, Zhang Chen, Xi Zhang, Jizhang Yu, Heng Xu, Jikai Cui, Yuan Li, Yuqing Niu, Cheng Zhou, Jiahong Xia, Jie Wu. Targeting PCSK9 Ameliorates Graft Vascular Disease in Mice by Inhibiting NLRP3 Inflammasome Activation in Vascular Smooth Muscle CellsFrontiers in Immunology 2022; 13 doi: 10.3389/fimmu.2022.894789
116
Jitendra Gupta, Reena Gupta. PCSK9 Biomarker and Key Modulator for Cardiovascular Disorders: Heralding a New Therapeutic Era and Their Future PerspectivesCurrent Molecular Pharmacology 2023; 16(8) doi: 10.2174/1874467216666221202144813
117
Guhan R Venkataraman, Manuel A Rivas. Rare and common variant discovery in complex disease: the IBD case studyHuman Molecular Genetics 2019; 28(R2): R162 doi: 10.1093/hmg/ddz189
118
Daniel Steffens, Peter Bramlage, Céline Scheeff, Mario Kasner, Adel Hassanein, Julian Friebel, Ursula Rauch-Kröhnert. PCSK9 inhibitors and cardiovascular outcomesExpert Opinion on Biological Therapy 2020; 20(1): 35 doi: 10.1080/14712598.2020.1677604
119
Sarah J. Beecroft, Phillipa J. Lamont, Samantha Edwards, Hayley Goullée, Mark R. Davis, Nigel G. Laing, Gianina Ravenscroft. The Impact of Next-Generation Sequencing on the Diagnosis, Treatment, and Prevention of Hereditary Neuromuscular DisordersMolecular Diagnosis & Therapy 2020; 24(6): 641 doi: 10.1007/s40291-020-00495-2
120
Harry Aldworth, Nigel M. Hooper. Post-translational regulation of the low-density lipoprotein receptor provides new targets for cholesterol regulationBiochemical Society Transactions 2024; 52(1): 431 doi: 10.1042/BST20230918
121
Yousuf Zafar, Yasar Sattar, Waqas Ullah, Sohaib Roomi, Mamoon-Ur- Rashid, Muhammad Shayan Khan, Laura Schmidt. Proprotein convertase subtilisin/Kexin type-9 (PCSK-9) inhibitors induced liver injury - a retrospective analysisJournal of Community Hospital Internal Medicine Perspectives 2020; 10(1): 32 doi: 10.1080/20009666.2019.1710952
122
Gopal Chandra Ghosh, Dhrubajyoti Bandyopadhyay, Raktim K. Ghosh, Samhati Mondal, Eyal Herzog. Effectiveness and Safety of Inclisiran, A Novel Long-Acting RNA Therapeutic Inhibitor of Proprotein Convertase Subtilisin/Kexin 9The American Journal of Cardiology 2018; 122(7): 1272 doi: 10.1016/j.amjcard.2018.06.023
123
Annemarie Wolf, Hanna Sarah Kutsche, Rolf Schreckenberg, Martin Weber, Ling Li, Susanne Rohrbach, Rainer Schulz, Klaus-Dieter Schlüter. Autocrine effects of PCSK9 on cardiomyocytesBasic Research in Cardiology 2020; 115(6) doi: 10.1007/s00395-020-00824-w
124
Lakshmi Lavanya Reddy, Swarup A. V. Shah, Chandrashekhar K. Ponde, Jamshed J. Dalal, Raj G. Jatale, Reeta J. Dalal, Rajesh M. Rajani, Sudhir K. Pillai, Chander V. Vanjani, Tester F. Ashavaid. Screening of PCSK9 and LDLR genetic variants in Familial Hypercholesterolemia (FH) patients in IndiaJournal of Human Genetics 2021; 66(10): 983 doi: 10.1038/s10038-021-00924-y
125
Busarin Arunsak, Wasana Pratchayasakul, Patchareeya Amput, Kenneth Chattipakorn, Theetouch Tosukhowong, Sasiwan Kerdphoo, Thidarat Jaiwongkum, Chanisa Thonusin, Siripong Palee, Nipon Chattipakorn, Siriporn C Chattipakorn. Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor exerts greater efficacy than atorvastatin on improvement of brain function and cognition in obese ratsArchives of Biochemistry and Biophysics 2020; 689: 108470 doi: 10.1016/j.abb.2020.108470
126
Emma M. O’Connell, Falk W. Lohoff. Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) in the Brain and Relevance for Neuropsychiatric DisordersFrontiers in Neuroscience 2020; 14 doi: 10.3389/fnins.2020.00609
127
Adi prasad Bodapati, Ayesha Hanif, Donatus K Okafor, Gitika Katyal, Gursharan Kaur, Hafsa Ashraf, Safeera Khan. PCSK-9 Inhibitors and Cardiovascular Outcomes: A Systematic Review With Meta-AnalysisCureus 2023;  doi: 10.7759/cureus.46605
128
Roberto Cemin, Simona Casablanca, Davide Ermacora, Massimo Daves. The Importance of Being Aware of Intrinsic Methods’ Limitation in Low-Density Lipoprotein Cholesterol Determination to Correctly Identify Cardiovascular Risk: Is Direct Determination Obtained with the Roche System Systematically Overestimating LDL in Very High-Risk Patients with Triglycerides Concentration of Less than (<2.25 mmol/L)?Journal of Clinical Medicine 2023; 12(13): 4422 doi: 10.3390/jcm12134422
129
BinBin Zheng-Lin, Alberto Ortiz. Lipid Management in Chronic Kidney Disease: Systematic Review of PCSK9 TargetingDrugs 2018; 78(2): 215 doi: 10.1007/s40265-017-0858-2
130
Anna Gluba-Brzózka, Beata Franczyk, Magdalena Rysz-Górzyńska, Janusz Ławiński, Jacek Rysz. Emerging Anti-Atherosclerotic TherapiesInternational Journal of Molecular Sciences 2021; 22(22): 12109 doi: 10.3390/ijms222212109
131
Vishnu Priya Pulipati, Michael H. Davidson. Recent advances and emerging therapies in management of dyslipidemiasTrends in Cardiovascular Medicine 2021; 31(7): 419 doi: 10.1016/j.tcm.2020.08.007
132
Constantine E Kosmas, Andreas Skavdis, Andreas Sourlas, Evangelia J Papakonstantinou, Edilberto Peña Genao, Rogers Echavarria Uceta, Eliscer Guzman. <p>Safety and Tolerability of PCSK9 Inhibitors: Current Insights</p>Clinical Pharmacology: Advances and Applications 2020; : 191 doi: 10.2147/CPAA.S288831
133
Ya-Nan Qiao, Yan-Li Zou, Shou-Dong Guo. Low-density lipoprotein particles in atherosclerosisFrontiers in Physiology 2022; 13 doi: 10.3389/fphys.2022.931931
134
Shengtao Xu, Shanshan Luo, Zheying Zhu, Jinyi Xu. Small molecules as inhibitors of PCSK9: Current status and future challengesEuropean Journal of Medicinal Chemistry 2019; 162: 212 doi: 10.1016/j.ejmech.2018.11.011
135
Maureen Sampson, Clarence Ling, Qian Sun, Roa Harb, Mohmed Ashmaig, Russell Warnick, Amar Sethi, James K. Fleming, James D. Otvos, Jeff W. Meeusen, Sarah R. Delaney, Allan S. Jaffe, Robert Shamburek, Marcelo Amar, Alan T. Remaley. A New Equation for Calculation of Low-Density Lipoprotein Cholesterol in Patients With Normolipidemia and/or HypertriglyceridemiaJAMA Cardiology 2020; 5(5): 540 doi: 10.1001/jamacardio.2020.0013
136
Wei Yin, Mark Rogge. Targeting RNA: A Transformative Therapeutic StrategyClinical and Translational Science 2019; 12(2): 98 doi: 10.1111/cts.12624
137
Leigh Goedeke, Alberto Canfrán-Duque, Noemi Rotllan, Balkrishna Chaube, Bonne M. Thompson, Richard G. Lee, Gary W. Cline, Jeffrey G. McDonald, Gerald I. Shulman, Miguel A. Lasunción, Yajaira Suárez, Carlos Fernández-Hernando. MMAB promotes negative feedback control of cholesterol homeostasisNature Communications 2021; 12(1) doi: 10.1038/s41467-021-26787-7
138
Nurjannatul Naim Kamaruddin, Nor Azwin Hajri, Yosie Andriani, Aina Farahiyah Abdul Manan, Tengku Sifzizul Tengku Muhammad, Habsah Mohamad. Acanthaster planci Inhibits PCSK9 and Lowers Cholesterol Levels in RatsMolecules 2021; 26(16): 5094 doi: 10.3390/molecules26165094
139
JinSook Yoon, DonO Kikkawa. Thyroid eye disease: From pathogenesis to targeted therapiesTaiwan Journal of Ophthalmology 2022; 12(1): 3 doi: 10.4103/tjo.tjo_51_21
140
Roberto CEMIN, Simona CASABLANCA, Davide ERMACORA, Massimo DAVES. Misurazione diretta del colesterolo-LDL e sue possibili conseguenze sulla terapia farmacologicaLa Rivista Italiana della Medicina di Laboratorio 2024; 19(4) doi: 10.23736/S1825-859X.23.00217-7
141
Saverio Muscoli, Mihaela Ifrim, Massimo Russo, Francesco Candido, Angela Sanseviero, Marialucia Milite, Marco Di Luozzo, Massimo Marchei, Giuseppe Sangiorgi. Current Options and Future Perspectives in the Treatment of DyslipidemiaJournal of Clinical Medicine 2022; 11(16): 4716 doi: 10.3390/jcm11164716
142
Marion Mussbacher, Manuel Salzmann, Barbara Haigl, José Basílio, Bernhard Hochreiter, Viola Gleitsmann, Bernhard Moser, Bastian Hoesel, Bianca E. Suur, Florian Puhm, Caroline Ungerböck, Mario Kuttke, Maria J. Forteza, Christoph J. Binder, Daniel F.J. Ketelhuth, Alice Assinger, Johannes A. Schmid. Ikk2-mediated inflammatory activation of arterial endothelial cells promotes the development and progression of atherosclerosisAtherosclerosis 2020; 307: 21 doi: 10.1016/j.atherosclerosis.2020.06.005
143
Andrew S. Bell, Josephin Wagner, Daniel B. Rosoff, Falk W. Lohoff. Proprotein convertase subtilisin/kexin type 9 (PCSK9) in the central nervous systemNeuroscience & Biobehavioral Reviews 2023; 149: 105155 doi: 10.1016/j.neubiorev.2023.105155
144
Zaheer Qureshi, Mikail Khanzada, Adnan Safi, Eeshal Fatima, Faryal Altaf, Timothy J. Vittorio. Hypercholesterolemia: a literature review on management using tafolecimab: a novel member of PCSK9 monoclonal antibodiesAnnals of Medicine & Surgery 2024; 86(5): 2818 doi: 10.1097/MS9.0000000000001945
145
Matthew Perry Koppinger, Marissa Anne Lopez-Pier, Rinku Skaria, Preston Royal Harris, John P. Konhilas. Lactobacillus reuteri attenuates cardiac injury without lowering cholesterol in low-density lipoprotein receptor-deficient mice fed standard chowAmerican Journal of Physiology-Heart and Circulatory Physiology 2020; 319(1): H32 doi: 10.1152/ajpheart.00569.2019
146
Sylwester Rogula, Ewelina Błażejowska, Aleksandra Gąsecka, Łukasz Szarpak, Milosz J. Jaguszewski, Tomasz Mazurek, Krzysztof J. Filipiak. Inclisiran—Silencing the Cholesterol, Speaking up the PrognosisJournal of Clinical Medicine 2021; 10(11): 2467 doi: 10.3390/jcm10112467
147
Valentina Rodriguez, Jonathan D. Newman, Arthur Z. Schwartzbard. Towards more specific treatment for diabetic dyslipidemiaCurrent Opinion in Lipidology 2018; 29(4): 307 doi: 10.1097/MOL.0000000000000528
148
Alfonso Soler-Bistué, Angeles Zorreguieta, Marcelo E. Tolmasky. Bridged Nucleic Acids ReloadedMolecules 2019; 24(12): 2297 doi: 10.3390/molecules24122297
149
Guangwei Huang, Xiyang Lu, Haiyan Zhou, Runhong Li, Qing Huang, Xinlin Xiong, Zhenhua Luo, Wei Li. PCSK9 inhibition protects against myocardial ischemia-reperfusion injury via suppressing autophagyMicrovascular Research 2022; 142: 104371 doi: 10.1016/j.mvr.2022.104371
150
Amino Acid Conjugates of 2-Mercaptobenzimidazole Ameliorates High-Fat Diet-Induced Hyperlipidemia in Rats via Attenuation of HMGCR, APOB, and PCSK9ACS Omega 2022; 7(44): 40502 doi: 10.1021/acsomega.2c05735
151
Mubashir Zafar. Exploring the Association of Lipid-Lowering Drugs with Diabetes: A Comprehensive ReviewTrends in Medical Research 2024; 19(1): 86 doi: 10.3923/tmr.2024.86.91
152
Amit Rout, Ajaypaul Sukhi, Rahul Chaudhary, Kevin P Bliden, Udaya S Tantry, Paul A Gurbel. Investigational drugs in phase II clinical trials for acute coronary syndromesExpert Opinion on Investigational Drugs 2020; 29(1): 33 doi: 10.1080/13543784.2020.1708324
153
Victoria Harbour, Candice Casillas, Zain Siddiqui, Biplab Sarkar, Sreya Sanyal, Peter Nguyen, Ka Kyung Kim, Abhishek Roy, Patricia Iglesias-Montoro, Saloni Patel, Frank Podlaski, Peter Tolias, William Windsor, Vivek Kumar. Regulation of Lipoprotein Homeostasis by Self-Assembling PeptidesACS Applied Bio Materials 2020; 3(12): 8978 doi: 10.1021/acsabm.0c01229
154
Ramyashree Tummala, Manasvi Gupta, Arvind Reddy Devanabanda, Dhrubajyoti Bandyopadhyay, Wilbert S. Aronow, Kausik K. Ray, Mamas Mamas, Raktim K. Ghosh. Bempedoic acid and its role in contemporary management of hyperlipidemia in atherosclerosisAnnals of Medicine 2022; 54(1): 1287 doi: 10.1080/07853890.2022.2059559
155
Marios Papasotiriou, Theodoros Ntrinias, Eirini Savvidaki, Evangelos Papachristou, Dimitrios S. Goumenos. Treatment of Mixed Dyslipidemia With Alirocumab in a Kidney Transplant Recipient: A Case ReportTransplantation Proceedings 2021; 53(9): 2775 doi: 10.1016/j.transproceed.2021.08.027
156
Carrie Palmer. New Directions in Managing DyslipidemiaThe Journal for Nurse Practitioners 2019; 15(1): 73 doi: 10.1016/j.nurpra.2018.08.033
157
Amber Carelse, Helgard M Rossouw, Nicolene Steyn, Janine Martins, Tahir S Pillay. Calculated LDL-cholesterol: comparability of the extended Martin/Hopkins, Sampson/NIH, Friedewald and four other equations in South African patientsJournal of Clinical Pathology 2023; : jcp-2023-208916 doi: 10.1136/jcp-2023-208916
158
Daniel B. Rosoff, Andrew S. Bell, Jeesun Jung, Josephin Wagner, Lucas A. Mavromatis, Falk W. Lohoff. Mendelian Randomization Study of PCSK9 and HMG-CoA Reductase Inhibition and Cognitive FunctionJournal of the American College of Cardiology 2022; 80(7): 653 doi: 10.1016/j.jacc.2022.05.041
159
Zhu Luo, Zhijun Huang, Feng Sun, Fang Guo, Yingying Wang, Sheena Kao, Guoping Yang, Jie Huang, Jiaxin Li, Sylvia Zhao, YanLing He. The clinical effects of inclisiran, a first-in-class LDL-C lowering siRNA therapy, on the LDL-C levels in Chinese patients with hypercholesterolemiaJournal of Clinical Lipidology 2023; 17(3): 392 doi: 10.1016/j.jacl.2023.04.010
160
Omonzejie E. Imaralu, Chandrakala Aluganti Narasimhulu, Pawan K. Singal, Dinender K. Singla. Role of proprotein convertase subtilisin/kexin type 9 (PCSK9) in diabetic complicationsCanadian Journal of Physiology and Pharmacology 2024; 102(01): 14 doi: 10.1139/cjpp-2023-0223
161
Adrianna Dec, Aleksandra Niemiec, Eliza Wojciechowska, Mateusz Maligłówka, Łukasz Bułdak, Aleksandra Bołdys, Bogusław Okopień. Inclisiran—A Revolutionary Addition to a Cholesterol-Lowering TherapyInternational Journal of Molecular Sciences 2023; 24(7): 6858 doi: 10.3390/ijms24076858
162
Gurpreet Kaur Batra, Chakrant Mothsara, Swati Sharma, Aishwarya Anand, Alka Bhatia, Shobhit Bhansali, Sant Ram, Arnab Pal, Amol N. Patil. Dose–Response Evaluation of Scopoletin, a Phytochemical, in a High-Fructose High-Fat Diet-Induced Dyslipidemia Model in Wistar RatsJournal of Medicinal Food 2023; 26(5): 319 doi: 10.1089/jmf.2022.K.0120
163
Candace L. Jackson, Yihong Deng, Xiaoxi Yao, Holly Van Houten, Nilay D. Shah, Stephen Kopecky. Proprotein convertase subtilisin/kexin type 9 inhibitor utilization and low-density lipoprotein-cholesterol control in familial hypercholesterolemiaJournal of Clinical Lipidology 2021; 15(2): 339 doi: 10.1016/j.jacl.2020.12.009
164
Chanisa Thonusin, Patcharapong Pantiya, Thidarat Jaiwongkam, Sasiwan Kerdphoo, Busarin Arunsak, Patchareeya Amput, Siripong Palee, Wasana Pratchayasakul, Nipon Chattipakorn, Siriporn C. Chattipakorn. A proprotein convertase subtilisin/kexin type 9 inhibitor provides comparable efficacy with lower detriment than statins on mitochondria of oxidative muscle of obese estrogen-deprived ratsMenopause 2020; 27(10): 1155 doi: 10.1097/GME.0000000000001586
165
Ioannis D. Karantas, Mehmet E. Okur, Neslihan Ü. Okur, Panoraia I. Siafaka. Dyslipidemia Management in 2020: An Update on Diagnosis and Therapeutic PerspectivesEndocrine, Metabolic & Immune Disorders - Drug Targets 2021; 21(5): 815 doi: 10.2174/1871530320666200810144004
166
Tao Cai, Nashmi Naife Al-Jubairi, Heitor O. Santos, Ivan G.O. de Souza, Youdong Chen. Does letrozole treatment have favorable effects on the lipid profile? A systematic review and meta-analysis of randomized clinical trialsSteroids 2021; 172: 108875 doi: 10.1016/j.steroids.2021.108875
167
Rajeev Chawla, S. V. Madhu, B. M. Makkar, Sujoy Ghosh, Banshi Saboo, Sanjay Kalra. RSSDI-ESI Clinical Practice Recommendations for the Management of Type 2 Diabetes Mellitus 2020International Journal of Diabetes in Developing Countries 2020; 40(S1): 1 doi: 10.1007/s13410-020-00819-2
168
Angela Lee, Sunny Wei, Adel Schwertani. A Notch more: Molecular players in bicuspid aortic valve diseaseJournal of Molecular and Cellular Cardiology 2019; 134: 62 doi: 10.1016/j.yjmcc.2019.05.018
169
George Valeriu Moldovan, Adina Huțanu, Liliana Demian, Laszlo Hadadi, Bogdan Mănescu, Minodora Dobreanu. The utility of MLPA in Familial Hypercholesterolemia diagnosisActa Marisiensis - Seria Medica 2021; 67(3): 162 doi: 10.2478/amma-2021-0021
170
Aida Collado, Elena Domingo, Laura Piqueras, Maria-Jesus Sanz. Primary hypercholesterolemia and development of cardiovascular disorders: Cellular and molecular mechanisms involved in low-grade systemic inflammation and endothelial dysfunctionThe International Journal of Biochemistry & Cell Biology 2021; 139: 106066 doi: 10.1016/j.biocel.2021.106066
171
Ada Cuevas, Rodrigo Alonso. Bempedoic acid: A new player in lipid-lowering therapiesJournal of Clinical Lipidology 2020; 14(5): 615 doi: 10.1016/j.jacl.2020.08.014
172
Ricardo Fontes‐Carvalho, Pedro Marques Silva, Elisabete Rodrigues, Francisco Araújo, Cristina Gavina, Jorge Ferreira, João Morais. Guia prático para a utilização dos inibidores da PCSK9 em PortugalRevista Portuguesa de Cardiologia 2019; 38(6): 391 doi: 10.1016/j.repc.2019.05.005
173
Bhavani Shankara Bagepally, Akhil Sasidharan. Incremental net benefit of lipid-lowering therapy with PCSK9 inhibitors: a systematic review and meta-analysis of cost-utility studiesEuropean Journal of Clinical Pharmacology 2022; 78(3): 351 doi: 10.1007/s00228-021-03242-6
174
Dominic Mitchell, Jason R. Guertin, Jacques LeLorier. Value of a Hypothetical Pharmacogenomic Test for the Diagnosis of Statin-Induced Myopathy in Patients at High Cardiovascular RiskMolecular Diagnosis & Therapy 2018; 22(6): 641 doi: 10.1007/s40291-018-0356-6
175
Hongju Liu, Huiyi Xie, Changqun Li, Lingling Wang, Qiling Chen, Xin Ouyang, Chong Yan. Diaporisoindole B Reduces Lipid Accumulation in THP-1 Macrophage Cells via MAPKs and PPARγ–LXRα Pathways and Promotes the Reverse Cholesterol Transport by Upregulating SR-B1 and LDLR in HepG2 CellsJournal of Natural Products 2022; 85(12): 2769 doi: 10.1021/acs.jnatprod.2c00715
176
Jianqiang Li, Carlotta Bollati, Martina Bartolomei, Angelica Mazzolari, Anna Arnoldi, Giulio Vistoli, Carmen Lammi. Hempseed (Cannabis sativa) Peptide H3 (IGFLIIWV) Exerts Cholesterol-Lowering Effects in Human Hepatic Cell LineNutrients 2022; 14(9): 1804 doi: 10.3390/nu14091804
177
Hong Lin, Juan I. Luengo. Exploiting binding-site arginines in drug design: Recent examplesBioorganic & Medicinal Chemistry Letters 2020; 30(19): 127442 doi: 10.1016/j.bmcl.2020.127442
178
S. K. Zyryanov, O. I. Butranova. New opportunities for lowering low-density lipoprotein cholesterol: comparative characteristics of PCSK9-targeted therapyRussian Journal of Cardiology 2022; 27(11): 5271 doi: 10.15829/1560-4071-2022-5271
179
Sanjana Jagannath, Nandini D. Chilkunda. High cholesterol-supplemented diet during gestation and lactation alters liver glycosaminoglycans and associated lipoprotein receptors and results in fat accumulation in adulthoodNutrition Research 2021; 93: 50 doi: 10.1016/j.nutres.2021.07.002
180
Grigoris Thermos, Konstantinos I. Tosios. Gingival Ischemia and Petechiae in a Patient Medicated With PCSK9 Inhibitor for Hypercholesterolemia: An Adverse Drug Event?Clinical Advances in Periodontics 2019; 9(1): 20 doi: 10.1002/cap.10043
181
Semira Abdi Beshir, Nadia Hussain, Asim Ahmed Elnor, Amira S. A. Said. Umbrella Review on Non-Statin Lipid-Lowering TherapyJournal of Cardiovascular Pharmacology and Therapeutics 2021; 26(5): 437 doi: 10.1177/10742484211002943
182
Ji Liu, Jin Chang, Ying Jiang, Xiandi Meng, Tianmeng Sun, Lanqun Mao, Qiaobing Xu, Ming Wang. Fast and Efficient CRISPR/Cas9 Genome Editing In Vivo Enabled by Bioreducible Lipid and Messenger RNA NanoparticlesAdvanced Materials 2019; 31(33) doi: 10.1002/adma.201902575
183
Roohollah Sattari, Abbasali Palizban, Hossein Khanahmad. Single-Strand DNA-Like Oligonucleotide Aptamer Against Proprotein Convertase Subtilisin/Kexin 9 Using CE-SELEX: PCSK9 Targeting SelectionCardiovascular Drugs and Therapy 2020; 34(4): 475 doi: 10.1007/s10557-020-06986-y
184
Pierre Giguère, Salin Nhean, Alice L. Tseng, Christine A. Hughes, Jonathan B. Angel. Getting to the Heart of the Matter: A Review of Drug Interactions Between HIV Antiretrovirals and Cardiology MedicationsCanadian Journal of Cardiology 2019; 35(3): 326 doi: 10.1016/j.cjca.2018.12.020
185
Dongdong Wang, Yang Yang, Yingnan Lei, Nikolay T. Tzvetkov, Xingde Liu, Andy Wai Kan Yeung, Suowen Xu, Atanas G. Atanasov, Qiang Ma. Targeting Foam Cell Formation in Atherosclerosis: Therapeutic Potential of Natural ProductsPharmacological Reviews 2019; 71(4): 596 doi: 10.1124/pr.118.017178
186
Alexander D. Mazura, Anke Ohler, Steffen E. Storck, Magdalena Kurtyka, Franka Scharfenberg, Sascha Weggen, Christoph Becker-Pauly, Claus U. Pietrzik. PCSK9 acts as a key regulator of Aβ clearance across the blood–brain barrierCellular and Molecular Life Sciences 2022; 79(4) doi: 10.1007/s00018-022-04237-x
187
Arcangelo Iannuzzi, Paolo Rubba, Marco Gentile, Vania Mallardo, Ilenia Calcaterra, Alessandro Bresciani, Giuseppe Covetti, Gianluigi Cuomo, Pasquale Merone, Anna Di Lorenzo, Roberta Alfieri, Emilio Aliberti, Francesco Giallauria, Matteo Nicola Dario Di Minno, Gabriella Iannuzzo. Carotid Atherosclerosis, Ultrasound and LipoproteinsBiomedicines 2021; 9(5): 521 doi: 10.3390/biomedicines9050521
188
Amy S. Etheridge, Paul J. Gallins, Dereje Jima, K. Alaine Broadaway, Mark J. Ratain, Erin Schuetz, Eric Schadt, Adrian Schroder, Cliona Molony, Yihui Zhou, Karen L. Mohlke, Fred A. Wright, Federico Innocenti. A New Liver Expression Quantitative Trait Locus Map From 1,183 Individuals Provides Evidence for Novel Expression Quantitative Trait Loci of Drug Response, Metabolic, and Sex‐Biased PhenotypesClinical Pharmacology & Therapeutics 2020; 107(6): 1383 doi: 10.1002/cpt.1751
189
Maria Lorenzi, Baishali Ambegaonkar, Carl A. Baxter, Jeroen Jansen, Michael J. Zoratti, Glenn Davies. Ezetimibe in high-risk, previously treated statin patients: a systematic review and network meta-analysis of lipid efficacyClinical Research in Cardiology 2019; 108(5): 487 doi: 10.1007/s00392-018-1379-z
190
Swapnil Raj, Liston Augustine Dsouza, Shailendra Pratap Singh, Abhinav Kanwal. Sirt6 Deacetylase: A Potential Key Regulator in the Prevention of Obesity, Diabetes and Neurodegenerative DiseaseFrontiers in Pharmacology 2020; 11 doi: 10.3389/fphar.2020.598326
191
Taher A. Salaheldin, Kavitha Godugu, Dhruba J. Bharali, Kazutoshi Fujioka, Nabil Elshourbagy, Shaker A. Mousa. Novel oral nano-hepatic targeted anti-PCSK9 in hypercholesterolemiaNanomedicine: Nanotechnology, Biology and Medicine 2022; 40: 102480 doi: 10.1016/j.nano.2021.102480
192
Brian Hon Yin Chung, Jeffrey Fong Ting Chau, Gane Ka-Shu Wong. Rare versus common diseases: a false dichotomy in precision medicinenpj Genomic Medicine 2021; 6(1) doi: 10.1038/s41525-021-00176-x
193
Thomas Duflot, Ly Tu, Matthieu Leuillier, Hind Messaoudi, Déborah Groussard, Guillaume Feugray, Saïda Azhar, Raphaël Thuillet, Fabrice Bauer, Marc Humbert, Vincent Richard, Christophe Guignabert, Jérémy Bellien. Preventing the Increase in Lysophosphatidic Acids: A New Therapeutic Target in Pulmonary Hypertension?Metabolites 2021; 11(11): 784 doi: 10.3390/metabo11110784
194
Zhixin Ma, Hongtao Liu, Shan Jiang, Wenya Li, Yue Li, Yiting Liu, Li Wang, Wenyan Li. Identification of benzothiazoles as novel PCSK9 inhibitorsBioorganic & Medicinal Chemistry Letters 2024; 97: 129542 doi: 10.1016/j.bmcl.2023.129542
195
Alacia J Tarpley. New Frontier in Lipids: PCSK9 Inhibitors and Implications for the Life Insurance IndustryJournal of Insurance Medicine 2018; 47(4): 230 doi: 10.17849/insm-47-4-1-6.1
196
Niki Katsiki, Vasilios G. Athyros, Dimitri P. Mikhailidis, Christos Mantzoros. Proprotein convertase subtilisin-kexin type 9 (PCSK9) inhibitors: Shaping the future after the further cardiovascular outcomes research with PCSK9 inhibition in subjects with elevated risk (FOURIER) trialMetabolism 2017; 74: 43 doi: 10.1016/j.metabol.2017.04.007
197
Si Cheng, Zhe Xu, Shengzhe Bian, Xi Chen, Yanfeng Shi, Yanran Li, Yunyun Duan, Yang Liu, Jinxi Lin, Yong Jiang, Jing Jing, Zixiao Li, Yilong Wang, Xia Meng, Yaou Liu, Mingyan Fang, Xin Jin, Xun Xu, Jian Wang, Chaolong Wang, Hao Li, Siyang Liu, Yongjun Wang. The STROMICS genome study: deep whole-genome sequencing and analysis of 10K Chinese patients with ischemic stroke reveal complex genetic and phenotypic interplayCell Discovery 2023; 9(1) doi: 10.1038/s41421-023-00582-8