Swine-origin influenza-virus-induced acute lung injury: Novel or classical pathogenesis?

Table 1 Summary of status of development and availability of A/California/7/2009 (H1N1)-like candidate vaccine viruses

Parent virus	Candidate vaccine virus	Type of virus or reassortant	Developing institute	Available from
A/California/7/2009 (H1N1)		Wild type virus		WHO CCs	NIBSC, UK
	X-179A	Classical	NYMC, USA	CDC, USA	NIBSC, UK
	IVR-153		CSL, Australia	CSL, Australia	NIBSC, UK
	X-181		NYMC, USA	NYMC, USA	NIBSC, UK
	X-181A
	NIBRG-121	Reverse genetics	NIBSC, UK	NIBSC, UK
	NIBRG-121xp
	NIIDRG-5		NIID, Japan	NIID, Japan
A/California/4/2009 (H1N1)		Wild type virus		WHO CCs
	CBER-RG2	Reverse genetics	CBER/FDA, USA	CDC, USA
A/Texas/5/2009 (H1N1)		Wild type virus		WHO CCs
	IDCDC-RG15	Reverse genetics	CDC, USA	CDC, USA
	IDCDC-RG20			CDC, USA
A/England/195/2009 (H1N1)		Wild type virus		WHO CCs	NIBSC, UK
	NIBRG-122	Reverse genetics	NIBSC, UK	NIBSC, UK
A/Texas/5/2009 (H1N1) and A/New York/18/2009 (H1N1)	IDCDC-RG18	Reverse genetics	CDC, USA	CDC, USA
A/New York/18/2009 (H1N1)		Wild type virus		WHO CCs	NIBSC, UK
	IDCDC-RG22	Reverse genetics	CDC, USA	CDC, USA

Adapted from WHO[65]. CBER/FDA: Center for Biologics Evaluation and Research/Food and Drug Administration; CDC: Centers for Disease Control and Prevention; NIBSC: National Institute for Biological Standards and Control; NIID: National Institute of Infectious Diseases; NYMC: New York Medical College; WHO CCs: World Health Organization Collaborating Centers on Influenza.