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May 26, 2014 (publication date) through Jul 15, 2025
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World Journal of Biological Chemistry
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1949-8454
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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
| For: | Qi QR, Yang ZM. Regulation and function of signal transducer and activator of transcription 3. World J Biol Chem 2014; 5(2): 231-239 [PMID: 24921012 DOI: 10.4331/wjbc.v5.i2.231] |
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| URL: | https://www.wjgnet.com/1949-8454/full/v5/i2/231.htm |
| Number | Citing Articles |
| 1 |
Kyung Don Ju, Joo Weon Lim, Hyeyoung Kim. Peroxisome Proliferator-activated Receptor-gamma Inhibits the Activation of STAT3 in Cerulein-stimulated Pancreatic Acinar Cells. Journal of Cancer Prevention 2017; 22(3): 189 doi: 10.15430/JCP.2017.22.3.189
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| 2 |
Rossana Cocchiola, Donatella Romaniello, Caterina Grillo, Fabio Altieri, Marcello Liberti, Fabio Massimo Magliocca, Silvia Chichiarelli, Ilaria Marrocco, Giuseppe Borgoni, Giacomo Perugia, Margherita Eufemi. Analysis of STAT3 post-translational modifications (PTMs) in human prostate cancer with different Gleason Score. Oncotarget 2017; 8(26): 42560 doi: 10.18632/oncotarget.17245
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| 3 |
YULIN XIONG, MING JIA, JING YUAN, CHANGJIANG ZHANG, YAN ZHU, XUEMEI KUANG, LIN LAN, XIAOHONG WANG. STAT3-regulated long non-coding RNAs lnc-7SK and lnc-IGF2-AS promote hepatitis C virus replication. Molecular Medicine Reports 2015; 12(5): 6738 doi: 10.3892/mmr.2015.4278
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| 4 |
Salman Goudarzi, Andrea Rivera, Arthur M. Butt, Sassan Hafizi. Gas6 Promotes Oligodendrogenesis and Myelination in the Adult Central Nervous System and After Lysolecithin-Induced Demyelination. ASN Neuro 2016; 8(5) doi: 10.1177/1759091416668430
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| 5 |
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| 6 |
Guanhuan Du, Junjun Chen, Yanni Wang, Tianyi Cao, Leilei Zhou, Yufeng Wang, Xiaozhe Han, Guoyao Tang. Differential expression of STAT-3 in subtypes of oral lichen planus: a preliminary study. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 2018; 125(3): 236 doi: 10.1016/j.oooo.2017.10.016
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| 7 |
Shih-Hsin Chang, Chi-Shin Hwang, Jiu-Haw Yin, Shang-Der Chen, Ding-I Yang. Oncostatin M-dependent Mcl-1 induction mediated by JAK1/2-STAT1/3 and CREB contributes to bioenergetic improvements and protective effects against mitochondrial dysfunction in cortical neurons. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 2015; 1853(10): 2306 doi: 10.1016/j.bbamcr.2015.05.014
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| 8 |
Elie Haddad. STAT3: too much may be worse than not enough!. Blood 2015; 125(4): 583 doi: 10.1182/blood-2014-11-610592
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| 9 |
Gaorui Wang, Ziyu Chen, Yingying Song, Hui Wu, Ming Chen, Shusheng Lai, Xiaojun Wu. Xueshuantong injection alleviates cerebral microcirculation disorder in middle cerebral artery occlusion/reperfusion rats by suppressing inflammation via JNK mediated JAK2/STAT3 and NF-κB signaling pathways. Journal of Ethnopharmacology 2022; 298: 115592 doi: 10.1016/j.jep.2022.115592
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| 10 |
Élodie Czuba, Marlène Deschuyter, Natacha Entz-Werlé, Georges Noël, Hélène Burckel. Overcoming the limits of pediatric brain tumor radiotherapy: The use of preclinical 3D models. Cancer/Radiothérapie 2024; 28(5): 424 doi: 10.1016/j.canrad.2024.06.003
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| 11 |
Jiye Wang, Guangji Zhang, Chunyan Dai, Xiufei Gao, Jianbin Wu, Li Shen, Zhe Chen, Pei Liu. Cryptotanshinone potentiates the antitumor effects of doxorubicin on gastric cancer cells via inhibition of STAT3 activity. Journal of International Medical Research 2017; 45(1): 220 doi: 10.1177/0300060516685513
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| 12 |
Bowen Liu, Tianjiao Wang, Huawei Wang, Lu Zhang, Feifei Xu, Runping Fang, Leilei Li, Xiaoli Cai, Yue Wu, Weiying Zhang, Lihong Ye. Oncoprotein HBXIP enhances HOXB13 acetylation and co-activates HOXB13 to confer tamoxifen resistance in breast cancer. Journal of Hematology & Oncology 2018; 11(1) doi: 10.1186/s13045-018-0577-5
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| 13 |
Ayşenur Çömez Baysal, Yasemin Çakır Kıymaz, Nil Özbilum Şahin, Mehmet Bakır. Investigation of Long Noncoding RNA‐NRAV and Long Noncoding RNA‐Lethe Expression in Crimean−Congo Hemorrhagic Fever. Journal of Medical Virology 2024; 96(12) doi: 10.1002/jmv.70142
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| 14 |
Hanna Glasebach, Steffen Rupp, Anke Burger-Kentischer. A standardizable human-based psoriasis skin model for drug development. Frontiers in Medicine 2025; 12 doi: 10.3389/fmed.2025.1539484
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| 15 |
Øystein Bruserud, Ina Nepstad, Michelle Hauge, Kimberley Joanne Hatfield, Håkon Reikvam. STAT3 as a possible therapeutic target in human malignancies: lessons from acute myeloid leukemia. Expert Review of Hematology 2015; 8(1): 29 doi: 10.1586/17474086.2015.971005
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| 16 |
Min Huang, Zhongjie Chen, Lu Zhang, Zhimin Huang, Yiying Chen, Jianrong Xu, Jian Zhang, Xiaohong Shu. Screening and biological evaluation of a novel STAT3 signaling pathway inhibitor against cancer. Bioorganic & Medicinal Chemistry Letters 2016; 26(21): 5172 doi: 10.1016/j.bmcl.2016.09.073
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| 17 |
Abdul Basit Baba, Ramesh Nivetha, Indranil Chattopadhyay, Siddavaram Nagini. Blueberry and malvidin inhibit cell cycle progression and induce mitochondrial-mediated apoptosis by abrogating the JAK/STAT-3 signalling pathway. Food and Chemical Toxicology 2017; 109: 534 doi: 10.1016/j.fct.2017.09.054
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| 18 |
Forkan Ahamed, Natalie Eppler, Elizabeth Jones, Yuxia Zhang. Understanding Macrophage Complexity in Metabolic Dysfunction-Associated Steatotic Liver Disease: Transitioning from the M1/M2 Paradigm to Spatial Dynamics. Livers 2024; 4(3): 455 doi: 10.3390/livers4030033
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| 19 |
J.W. Chiao, Maxime Melikian, Liying Han, Chengsen Xue, Allen Tsao, Luxi Wang, Simon K. Mencher, John Fallon, Karim Solangi, Gildas Bertho, Long G. Wang. Interaction of a small molecule Natura-α and STAT3-SH2 domain to block Y705 phosphorylation and inhibit lupus nephritis. Biochemical Pharmacology 2016; 99: 123 doi: 10.1016/j.bcp.2015.11.018
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| 20 |
Ergul Dilan Celebi-Birand, Elif Tugce Karoglu, Fusun Doldur-Balli, Michelle M. Adams. Molecules to Medicine with mTOR. 2016; : 185 doi: 10.1016/B978-0-12-802733-2.00007-4
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| 21 |
Katarzyna Kamińska, Anna M. Czarnecka, Bernard Escudier, Fei Lian, Cezary Szczylik. Interleukin-6 as an emerging regulator of renal cell cancer. Urologic Oncology: Seminars and Original Investigations 2015; 33(11): 476 doi: 10.1016/j.urolonc.2015.07.010
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| 22 |
Lin Yang, Cui Ma, Lixin Zhang, Min Zhang, Fei Li, Chen Zhang, Xiufeng Yu, Xiaoying Wang, Siyu He, Daling Zhu, Yinli Song. 15-Lipoxygenase-2/15(S)-hydroxyeicosatetraenoic acid regulates cell proliferation and metastasis via the STAT3 pathway in lung adenocarcinoma. Prostaglandins & Other Lipid Mediators 2018; 138: 31 doi: 10.1016/j.prostaglandins.2018.07.003
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| 23 |
Joaquim Bosch-Barrera, Bernardo Queralt, Javier A. Menendez. Targeting STAT3 with silibinin to improve cancer therapeutics. Cancer Treatment Reviews 2017; 58: 61 doi: 10.1016/j.ctrv.2017.06.003
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| 24 |
Verónica G. Piazza, Nadia S. Cicconi, Carolina S. Martinez, Fernando P. Dominici, Johanna G. Miquet, Ana I. Sotelo. Liver impact of growth hormone (GH) intermittent treatment during the growth period in mice. Molecular and Cellular Endocrinology 2023; : 111911 doi: 10.1016/j.mce.2023.111911
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| 25 |
Andrea C. Rossetti, Maria Serena Paladini, Cesar Augusto Brüning, Vittoria Spero, Maria Grazia Cattaneo, Giorgio Racagni, Mariusz Papp, Marco A. Riva, Raffaella Molteni. Involvement of the IL-6 Signaling Pathway in the Anti-Anhedonic Effect of the Antidepressant Agomelatine in the Chronic Mild Stress Model of Depression. International Journal of Molecular Sciences 2022; 23(20): 12453 doi: 10.3390/ijms232012453
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| 26 |
Huaying Yan, Linmei Tang, Zhu Yuan, Yaodan Zhang. The effects of STAT3 acetylation on the transcriptional activity and tumorigenesis. Biochemical Pharmacology 2025; 240: 117076 doi: 10.1016/j.bcp.2025.117076
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| 27 |
Xiaokui Yu, Li He, Peng Cao, Qiang Yu, Irina V Lebedeva. Eriocalyxin B Inhibits STAT3 Signaling by Covalently Targeting STAT3 and Blocking Phosphorylation and Activation of STAT3. PLOS ONE 2015; 10(5): e0128406 doi: 10.1371/journal.pone.0128406
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| 28 |
Alessia Tassoni, Alex Gutteridge, Amanda C. Barber, Andrew Osborne, Keith R. Martin. Molecular Mechanisms Mediating Retinal Reactive Gliosis Following Bone Marrow Mesenchymal Stem Cell Transplantation. Stem Cells 2015; 33(10): 3006 doi: 10.1002/stem.2095
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| 29 |
Tiina Jokela, Riikka Kärnä, Leena Rauhala, Genevieve Bart, Sanna Pasonen-Seppänen, Sanna Oikari, Markku I. Tammi, Raija H. Tammi. Human Keratinocytes Respond to Extracellular UTP by Induction of Hyaluronan Synthase 2 Expression and Increased Hyaluronan Synthesis. Journal of Biological Chemistry 2017; 292(12): 4861 doi: 10.1074/jbc.M116.760322
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| 30 |
Milad Ashrafizadeh, Chakrabhavi D. Mohan, Shobith Rangappa, Ali Zarrabi, Kiavash Hushmandi, Alan Prem Kumar, Gautam Sethi, Kanchugarakoppal S. Rangappa. Noncoding RNAs as regulators of STAT3 pathway in gastrointestinal cancers: Roles in cancer progression and therapeutic response. Medicinal Research Reviews 2023; 43(5): 1263 doi: 10.1002/med.21950
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| 31 |
Hyoin Kim, Jong Kyung Sonn. Rac1 promotes chondrogenesis by regulating STAT3 signaling pathway. Cell Biology International 2016; 40(9): 976 doi: 10.1002/cbin.10635
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| 32 |
Meichao Zhang, Yiling Meng, Yingxia Ying, Pingting Zhou, Suning Zhang, Yong Fang, Yuan Yao, Dong Li. Selective activation of STAT3 and STAT5 dictates the fate of myeloid progenitor cells. Cell Death Discovery 2023; 9(1) doi: 10.1038/s41420-023-01575-y
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| 33 |
Nobuhiro Kurabayashi, Minh Dang Nguyen, Kamon Sanada. DYRK1A overexpression enhancesSTATactivity and astrogliogenesis in a Down syndrome mouse model. EMBO reports 2015; 16(11): 1548 doi: 10.15252/embr.201540374
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| 34 |
Ling Gao, Feng-Sheng Li, Xiao-Hua Chen, Qiao-Wei Liu, Jiang-Bin Feng, Qing-Jie Liu, Xu Su. Radiation Induces Phosphorylation of STAT3 in a Dose- and Time-dependent Manner. Asian Pacific Journal of Cancer Prevention 2014; 15(15): 6161 doi: 10.7314/APJCP.2014.15.15.6161
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| 35 |
Brigitte Bauvois, Elodie Pramil, Ludovic Jondreville, Claire Quiney, Florence Nguyen-Khac, Santos A. Susin. Activation of Interferon Signaling in Chronic Lymphocytic Leukemia Cells Contributes to Apoptosis Resistance via a JAK-Src/STAT3/Mcl-1 Signaling Pathway. Biomedicines 2021; 9(2): 188 doi: 10.3390/biomedicines9020188
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| 36 |
Xiaoqin Zhang, Wenqian Zhou, Yangyang Niu, Saiya Zhu, Yingying Zhang, Xiaogang Li, Chen Yu. Lysyl oxidase promotes renal fibrosis via accelerating collagen cross‐link driving by β‐arrestin/ERK/STAT3 pathway. The FASEB Journal 2022; 36(8) doi: 10.1096/fj.202200573R
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| 37 |
Izabela Szulc-Kielbik, Michal Kielbik, Marek Nowak, Magdalena Klink. The implication of IL-6 in the invasiveness and chemoresistance of ovarian cancer cells. Systematic review of its potential role as a biomarker in ovarian cancer patients. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 2021; 1876(2): 188639 doi: 10.1016/j.bbcan.2021.188639
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| 38 |
Nur Amalina Amirullah, Erlina Abdullah, Nurhayati Zainal Abidin, Noorlidah Abdullah, Sivakumar Manickam. Therapeutic potential of mushrooms: A review on NF-κB modulation in chronic inflammation. Food Bioscience 2024; 62: 105059 doi: 10.1016/j.fbio.2024.105059
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| 39 |
Celia María Curieses Andrés, Fernando Lobo, José Manuel Pérez de la Lastra, Elena Bustamante Munguira, Celia Andrés Juan, Eduardo Pérez-Lebeña. Cysteine Alkylation in Enzymes and Transcription Factors: A Therapeutic Strategy for Cancer. Cancers 2025; 17(11): 1876 doi: 10.3390/cancers17111876
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| 40 |
Ya-Nan Liang, Zuwang Zhang, Ji Song, Fuwei Yang, Pan Yang, Xi Wei. Role of STAT3 Expression in Thyroid Cancer: A Meta-Analysis and Systematic Review Based on the Chinese Population. Evidence-Based Complementary and Alternative Medicine 2022; 2022: 1 doi: 10.1155/2022/1116535
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| 41 |
Chunyan Luo, Yuwen Ruan, Peixue Sun, Haoran Wang, Weihua Yang, Yuankai Gong, Decheng Wang. The Role of Transcription Factors in Coronary Artery Disease and Myocardial Infarction. Frontiers in Bioscience-Landmark 2022; 27(12) doi: 10.31083/j.fbl2712329
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| 42 |
Lior Goldberg, Mor Abutbul-Amitai, Gideon Paret, Yael Nevo-Caspi. Alternative Splicing ofSTAT3Is Affected by RNA Editing. DNA and Cell Biology 2017; 36(5): 367 doi: 10.1089/dna.2016.3575
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| 43 |
Changhe Zhang, Hong Xu, Zhenping Zhou, Ye Tian, Xiaofei Cao, Guochang Cheng, Qinghong Liu. Blocking of the EGFR‑STAT3 signaling pathway through afatinib treatment inhibited the intrahepatic cholangiocarcinoma. Experimental and Therapeutic Medicine 2018; doi: 10.3892/etm.2018.6038
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| 44 |
Jianming Chen, Ping Han, Xiumei Liu, Xubo Wang. Characterization of Japanese flounder (Paralichthys olivaceus) STAT members: An immune-related gene family involved in Edwardsiella tarda and temperature stress. Fish & Shellfish Immunology 2023; 138: 108818 doi: 10.1016/j.fsi.2023.108818
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| 45 |
Kun Ji, Mingxuan Zhang, Qi Chu, Yong Gan, Hui Ren, Liyan Zhang, Liwei Wang, Xiaoxiu Li, Wei Wang, Xianglin Shi. The Role of p-STAT3 as a Prognostic and Clinicopathological Marker in Colorectal Cancer: A Systematic Review and Meta-Analysis. PLOS ONE 2016; 11(8): e0160125 doi: 10.1371/journal.pone.0160125
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| 46 |
Marcin L. Sander, Volker Eulenburg, Tatsuo Maeyashiki, Jae-Hwi Jang, Sarah D. Müller, Sebastian N. Stehr, Wolfgang Jungraithmayr, Tobias Piegeler. Remote Kidney and Liver Injury After Transplantation of Lung Allografts in an Allogeneic Mouse Model. Transplantation Proceedings 2024; 56(9): 2046 doi: 10.1016/j.transproceed.2024.10.020
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Yulin Xiong, Jing Yuan, Changjiang Zhang, Yan Zhu, Xuemei Kuang, Lin Lan, Xiaohong Wang. The STAT3-regulated long non-coding RNA Lethe promote the HCV replication. Biomedicine & Pharmacotherapy 2015; 72: 165 doi: 10.1016/j.biopha.2015.04.019
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Yun Yu, Didi Chen, Tao Wu, Haizhen Lin, Lianli Ni, Hehuan Sui, Sisi Xiao, Canwei Wang, Suping Jiang, Huanle Pan, Shaotang Li, Xiance Jin, Congying Xie, Ri Cui. Dihydroartemisinin enhances the anti-tumor activity of oxaliplatin in colorectal cancer cells by altering PRDX2-reactive oxygen species-mediated multiple signaling pathways. Phytomedicine 2022; 98: 153932 doi: 10.1016/j.phymed.2022.153932
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| 49 |
Aleksandar Jovanović. Cardioprotective signalling: Past, present and future. European Journal of Pharmacology 2018; 833: 314 doi: 10.1016/j.ejphar.2018.06.029
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AS Yar Saglam, E Alp, Z Elmazoglu, S Menevse. Treatment with cucurbitacin B alone and in combination with gefitinib induces cell cycle inhibition and apoptosis via EGFR and JAK/STAT pathway in human colorectal cancer cell lines. Human & Experimental Toxicology 2016; 35(5): 526 doi: 10.1177/0960327115595686
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Lie-Hao Jiang, Ming-Hua Ge, Xiu-Xiu Hou, Jun Cao, Si-Si Hu, Xiao-Xiao Lu, Jing Han, Yi-Chen Wu, Xiang Liu, Xin Zhu, Lian-Lian Hong, Pei Li, Zhi-Qiang Ling. miR-21 regulates tumor progression through the miR-21-PDCD4-Stat3 pathway in human salivary adenoid cystic carcinoma. Laboratory Investigation 2015; 95(12): 1398 doi: 10.1038/labinvest.2015.105
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Yang Yang, Wei Hu, Shouyin Di, Zhiqiang Ma, Chongxi Fan, Dongjin Wang, Shuai Jiang, Yue Li, Qing Zhou, Tian Li, Erping Luo. Tackling myocardial ischemic injury: the signal transducer and activator of transcription 3 (STAT3) at a good site. Expert Opinion on Therapeutic Targets 2017; 21(2): 215 doi: 10.1080/14728222.2017.1275566
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Wen-Xiang Cheng, Shan Zhong, Xiang-Bo Meng, Nian-Ye Zheng, Peng Zhang, Yun Wang, Ling Qin, Xin-Luan Wang. Cinnamaldehyde Inhibits Inflammation of Human Synoviocyte Cells Through Regulation of Jak/Stat Pathway and Ameliorates Collagen-Induced Arthritis in Rats. The Journal of Pharmacology and Experimental Therapeutics 2020; 373(2): 302 doi: 10.1124/jpet.119.262907
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Alexandra Weyrich, Stephanie Benz, Stephan Karl, Marie Jeschek, Katarina Jewgenow, Joerns Fickel. Paternal heat exposure causesDNAmethylation and gene expression changes ofStat3in Wild guinea pig sons. Ecology and Evolution 2016; 6(9): 2657 doi: 10.1002/ece3.1993
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| 56 |
Beatriz Ferrer, Harshini Suresh, Abel Santamaria, João Batista Rocha, Aaron B. Bowman, Michael Aschner. The antioxidant role of STAT3 in methylmercury-induced toxicity in mouse hypothalamic neuronal GT1-7 cell line. Free Radical Biology and Medicine 2021; 171: 245 doi: 10.1016/j.freeradbiomed.2021.05.024
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JingJing Wu, Qing Tang, LiJuan Yang, YuQing Chen, Fang Zheng, Swei Sunny Hann. Interplay of DNA methyltransferase 1 and EZH2 through inactivation of Stat3 contributes to β-elemene-inhibited growth of nasopharyngeal carcinoma cells. Scientific Reports 2017; 7(1) doi: 10.1038/s41598-017-00626-6
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Jianfang Chen, Wei Zhang, Qing Xu, Jihua Zhang, Wei Chen, Zhengrong Xu, Chaosheng Li, Zhenhua Wang, Yao Zhang, Yulan Zhen, Jianqiang Feng, Jun Chen, Jingfu Chen. Ang-(1-7) protects HUVECs from high glucose-induced injury and inflammation via inhibition of the JAK2/STAT3 pathway. International Journal of Molecular Medicine 2018; doi: 10.3892/ijmm.2018.3507
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Chelsea Pinkham, Soyeon An, Lindsay Lundberg, Neha Bansal, Ashwini Benedict, Aarthi Narayanan, Kylene Kehn-Hall. The role of signal transducer and activator of transcription 3 in Rift Valley fever virus infection. Virology 2016; 496: 175 doi: 10.1016/j.virol.2016.06.004
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