For: | Vugmeyster Y, Xu X, Theil FP, Khawli LA, Leach MW. Pharmacokinetics and toxicology of therapeutic proteins: Advances and challenges. World J Biol Chem 2012; 3(4): 73-92 [PMID: 22558487 DOI: 10.4331/wjbc.v3.i4.73] |
---|---|
URL: | https://www.wjgnet.com/1949-8454/full/v3/i4/73.htm |
Number | Citing Articles |
1 |
Yuhua Li, Qiang Meng, Mengbi Yang, Dongyang Liu, Xiangyu Hou, Lan Tang, Xin Wang, Yuanfeng Lyu, Xiaoyan Chen, Kexin Liu, Ai-Ming Yu, Zhong Zuo, Huichang Bi. Current trends in drug metabolism and pharmacokinetics. Acta Pharmaceutica Sinica B 2019; 9(6): 1113 doi: 10.1016/j.apsb.2019.10.001
|
2 |
Danilo Costa Geraldes, Viviane Lucia Beraldo-de-Araújo, Boris Odelion Pichihua Pardo, Adalberto Pessoa Junior, Marco Antônio Stephano, Laura de Oliveira-Nascimento. Protein drug delivery: current dosage form profile and formulation strategies. Journal of Drug Targeting 2020; 28(4): 339 doi: 10.1080/1061186X.2019.1669043
|
3 |
Andrew Lucas, Lauren Price, Allison Schorzman, Mallory Storrie, Joseph Piscitelli, Juan Razo, William Zamboni. Factors Affecting the Pharmacology of Antibody–Drug Conjugates. Antibodies 2018; 7(1): 10 doi: 10.3390/antib7010010
|
4 |
Emily Ann Todd, Nicholas A. Mirsky, Bruno Luís Graciliano Silva, Ankita Raja Shinde, Aris R. L. Arakelians, Vasudev Vivekanand Nayak, Rosemary Adriana Chiérici Marcantonio, Nikhil Gupta, Lukasz Witek, Paulo G. Coelho. Functional Scaffolds for Bone Tissue Regeneration: A Comprehensive Review of Materials, Methods, and Future Directions. Journal of Functional Biomaterials 2024; 15(10): 280 doi: 10.3390/jfb15100280
|
5 |
Ivo P. Nnane. Reference Module in Chemistry, Molecular Sciences and Chemical Engineering. 2018; doi: 10.1016/B978-0-12-409547-2.14439-7
|
6 |
A. Zaghmi, E. Mendez-Villuendas, A.A. Greschner, J.Y. Liu, H.W. de Haan, M.A. Gauthier. Mechanisms of activity loss for a multi-PEGylated protein by experiment and simulation. Materials Today Chemistry 2019; 12: 121 doi: 10.1016/j.mtchem.2018.12.007
|
7 |
Hendrik Neubert, Scott Fountain, Lindsay King, Tracey Clark, Yan Weng, Denise M O‘Hara, Wenlin Li, Sheldon Leung, Chad Ray, Joe Palandra, Mireia Fernández Ocaña, Jianqing Chen, Chengjie Ji, Mengmeng Wang, Kimberly Long, Boris Gorovits, Eric Fluhler. Tissue Bioanalysis of Biotherapeutics And Drug Targets to Support Pk/Pd. Bioanalysis 2012; 4(21): 2589 doi: 10.4155/bio.12.234
|
8 |
Yulia Vugmeyster, George Locke, Christoph Helwig, P. Alexander Rolfe, Jennifer Q. Dong, Karthik Venkatakrishnan. Risk assessment of drug–drug interaction potential for bintrafusp alfa with cytochrome P4503A4 substrates: A totality of evidence approach. Clinical and Translational Science 2022; 15(12): 2838 doi: 10.1111/cts.13413
|
9 |
Liang Zhang, Tejas Navaratna, Greg M. Thurber. A Helix-Stabilizing Linker Improves Subcutaneous Bioavailability of a Helical Peptide Independent of Linker Lipophilicity. Bioconjugate Chemistry 2016; 27(7): 1663 doi: 10.1021/acs.bioconjchem.6b00209
|
10 |
Catherine H. Smith. Rook's Textbook of Dermatology, Ninth Edition. 2016; : 1 doi: 10.1002/9781118441213.rtd0014
|
11 |
Zheng Cao, Chaoyong Liu, Jing Wen, Yunfeng Lu. Innovative Formulation Platform: Paving the Way for Superior Protein Therapeutics with Enhanced Efficacy and Broadened Applications. Advanced Materials 2024; doi: 10.1002/adma.202403116
|
12 |
Elena Maestri, Marta Marmiroli, Nelson Marmiroli. Bioactive peptides in plant-derived foodstuffs. Journal of Proteomics 2016; 147: 140 doi: 10.1016/j.jprot.2016.03.048
|
13 |
Raisa Yu. Kiseleva, Patrick M. Glassman, Colin F. Greineder, Elizabeth D. Hood, Vladimir V. Shuvaev, Vladimir R. Muzykantov. Targeting therapeutics to endothelium: are we there yet?. Drug Delivery and Translational Research 2018; 8(4): 883 doi: 10.1007/s13346-017-0464-6
|
14 |
Jinkyu Lee, Sajeesh Kumar Madhurakkat Perikamana, Taufiq Ahmad, Min Suk Lee, Hee Seok Yang, Do-Gyoon Kim, Kyobum Kim, Bosun Kwon, Heungsoo Shin. Controlled Retention of BMP-2-Derived Peptide on Nanofibers Based on Mussel-Inspired Adhesion for Bone Formation. Tissue Engineering Part A 2017; 23(7-8): 323 doi: 10.1089/ten.tea.2016.0363
|
15 |
Shufang Liu, Dhaval K. Shah. Mathematical Models to Characterize the Absorption, Distribution, Metabolism, and Excretion of Protein Therapeutics. Drug Metabolism and Disposition 2022; 50(6): 867 doi: 10.1124/dmd.121.000460
|
16 |
Shengsheng Xu, Igor A. Kaltashov. Evaluation of Gallium as a Tracer of Exogenous Hemoglobin–Haptoglobin Complexes for Targeted Drug Delivery Applications. Journal of the American Society for Mass Spectrometry 2016; 27(12): 2025 doi: 10.1007/s13361-016-1484-z
|
17 |
Sareh Azadi, Mohammad Ali Yazdanpanah, Ali Afshari, Niloofar Alahdad, Solmaz Chegeni, Abdolhamid Angaji, Seyed Mahdi Rezayat, Shima Tavakol. Bioinspired synthetic peptide-based biomaterials regenerate bone through biomimicking of extracellular matrix. Journal of Tissue Engineering 2024; 15 doi: 10.1177/20417314241303818
|
18 |
Bahareh Farasati Far, Maryam Safaei, Fatemeh Mokhtari, Mohammad Sadegh Fallahi, Mohammad Reza Naimi-Jamal. Fundamental concepts of protein therapeutics and spacing in oncology: an updated comprehensive review. Medical Oncology 2023; 40(6) doi: 10.1007/s12032-023-02026-5
|
19 |
Miia Kovalainen, Juha Mönkäre, Joakim Riikonen, Ullamari Pesonen, Maria Vlasova, Jarno Salonen, Vesa-Pekka Lehto, Kristiina Järvinen, Karl-Heinz Herzig. Novel Delivery Systems for Improving the Clinical Use of Peptides. Pharmacological Reviews 2015; 67(3): 541 doi: 10.1124/pr.113.008367
|
20 |
Andrew T. Lucas, Ryan Robinson, Allison N. Schorzman, Joseph A. Piscitelli, Juan F. Razo, William C. Zamboni. Pharmacologic Considerations in the Disposition of Antibodies and Antibody-Drug Conjugates in Preclinical Models and in Patients. Antibodies 2019; 8(1): 3 doi: 10.3390/antib8010003
|
21 |
Rod Chalk, William E. P. Greenland, Tiago Moreira, Jesse Coker, Shubhashish M. M. Mukhopadhyay, Eleanor Williams, Charlotte Manning, Tina Bohstedt, Rama McCrorie, Alejandra Fernandez-Cid, Nicola A. Burgess-Brown. Identification, mapping and relative quantitation of SARS-CoV-2 Spike glycopeptides by Mass-Retention Time Fingerprinting. Communications Biology 2021; 4(1) doi: 10.1038/s42003-021-02455-w
|
22 |
Theresa Yuraszeck, Megan Gibbs. Pharmaceutical Sciences Encyclopedia. 2015; : 1 doi: 10.1002/9780470571224.pse559
|
23 |
Brooke M. Rock, Robert S. Foti. Pharmacokinetic and Drug Metabolism Properties of Novel Therapeutic Modalities. Drug Metabolism and Disposition 2019; 47(10): 1097 doi: 10.1124/dmd.119.088708
|
24 |
Jacqueline G. Gerhart, Stephen Balevic, Jaydeep Sinha, Eliana M. Perrin, Jian Wang, Andrea N. Edginton, Daniel Gonzalez. Characterizing Pharmacokinetics in Children With Obesity—Physiological, Drug, Patient, and Methodological Considerations. Frontiers in Pharmacology 2022; 13 doi: 10.3389/fphar.2022.818726
|
25 |
PHARMACEUTICAL AND CLINICAL CHALLENGES OF BIOLOGICAL MEDICINES: ONGOING HURDLES FROM DRUG DEVELOPMENT TO THERAPEUTIC APPLICATIONS. Asian Journal of Pharmaceutical and Clinical Research 2024; : 9 doi: 10.22159/ajpcr.2024v17i8.51398
|
26 |
Hossein Salimi-Moosavi, Marcus Soto. A Non-radiometric Approach to Determine Tissue Vascular Blood Volume in Biodistribution Studies. The AAPS Journal 2022; 24(6) doi: 10.1208/s12248-022-00770-6
|
27 |
Sahar Awwad, Abeer H A Mohamed Ahmed, Garima Sharma, Jacob S Heng, Peng T Khaw, Steve Brocchini, Alastair Lockwood. Principles of pharmacology in the eye. British Journal of Pharmacology 2017; 174(23): 4205 doi: 10.1111/bph.14024
|
28 |
Amita Datta-Mannan, Benjamin Yaden, Venkatesh Krishnan, Bryan E. Jones, Johnny E. Croy. An Engineered Human Follistatin Variant: Insights into the Pharmacokinetic and Pharmocodynamic Relationships of a Novel Molecule with Broad Therapeutic Potential. The Journal of Pharmacology and Experimental Therapeutics 2013; 344(3): 616 doi: 10.1124/jpet.112.201491
|
29 |
Ludivine Fronton, Sabine Pilari, Wilhelm Huisinga. Monoclonal antibody disposition: a simplified PBPK model and its implications for the derivation and interpretation of classical compartment models. Journal of Pharmacokinetics and Pharmacodynamics 2014; 41(2): 87 doi: 10.1007/s10928-014-9349-1
|
30 |
Gilad Kaplan, Fred Lee, Masanori Onda, Emily Kolyvas, Gaurav Bhardwaj, David Baker, Ira Pastan. Protection of the Furin Cleavage Site in Low-Toxicity Immunotoxins Based on Pseudomonas Exotoxin A. Toxins 2016; 8(8): 217 doi: 10.3390/toxins8080217
|
31 |
Patrick McMullen, Liang Fang, Qi Qiao, Qing Shao, Shaoyi Jiang. Impacts of a Zwitterionic Peptide on its Fusion Protein. Bioconjugate Chemistry 2022; 33(8): 1485 doi: 10.1021/acs.bioconjchem.2c00176
|
32 |
Issa Sadeghian, Mina Akbarpour, Fatemeh Mohammad Alizadeh Chafjiri, Pegah Mohammad Alizadeh Chafjiri, Reza Heidari, Mohammad Hossein Morowvat, Razieh Sadeghian, Mohammad Javad Raee, Manica Negahdaripour. Potential of oligonucleotide- and protein/peptide-based therapeutics in the management of toxicant/stressor-induced diseases. Naunyn-Schmiedeberg's Archives of Pharmacology 2024; 397(3): 1275 doi: 10.1007/s00210-023-02683-3
|
33 |
Zoya Siddiqui, William Frishman. New Oral PCSK9 Inhibitor: “MK-0616”. Cardiology in Review 2024; doi: 10.1097/CRD.0000000000000655
|
34 |
Guilhem Bousquet, Jean-Paul Feugeas, Yuchen Gu, Christophe Leboeuf, Morad El Bouchtaoui, He Lu, Marc Espié, Anne Janin, Melanie Di Benedetto. High expression of apoptosis protein (Api-5) in chemoresistant triple-negative breast cancers: an innovative target. Oncotarget 2019; 10(61): 6577 doi: 10.18632/oncotarget.27312
|
35 |
Leijun Hu, Ryan J. Hansen. Issues, challenges, and opportunities in model-based drug development for monoclonal antibodies. Journal of Pharmaceutical Sciences 2013; 102(9): 2898 doi: 10.1002/jps.23504
|
36 |
Lei Wang, Wei Qiang, Zeneng Cheng. Allometric Scaling of Therapeutic Monoclonal Antibodies Using Antigen Concentration as a Correction Factor: Application to the Human Clearance Prediction. Journal of Pharmaceutical Sciences 2016; 105(3): 1335 doi: 10.1016/j.xphs.2015.12.021
|
37 |
Richard J. D. Hatley, Simon J. F. Macdonald, Robert J. Slack, Joelle Le, Steven B. Ludbrook, Pauline T. Lukey. An αv‐RGD Integrin Inhibitor Toolbox: Drug Discovery Insight, Challenges and Opportunities. Angewandte Chemie International Edition 2018; 57(13): 3298 doi: 10.1002/anie.201707948
|
38 |
Jay Tibbitts, David Canter, Ryan Graff, Alison Smith, Leslie A. Khawli. Key factors influencing ADME properties of therapeutic proteins: A need for ADME characterization in drug discovery and development. mAbs 2016; 8(2): 229 doi: 10.1080/19420862.2015.1115937
|
39 |
Shan Chung, Van Nguyen, Yuwen Linda Lin, Julien Lafrance-Vanasse, Suzie J. Scales, Kevin Lin, Rong Deng, Kathi Williams, Gizette Sperinde, Juan Jenny Li, Kai Zheng, Siddharth Sukumaran, Devin Tesar, James A. Ernst, Saloumeh Fischer, Greg A. Lazar, Saileta Prabhu, An Song. Anin vitroFcRn- dependent transcytosis assay as a screening tool for predictive assessment of nonspecific clearance of antibody therapeutics in humans. mAbs 2019; 11(5): 942 doi: 10.1080/19420862.2019.1605270
|
40 |
Eric Ezan, François Becher, François Fenaille. Assessment of the metabolism of therapeutic proteins and antibodies. Expert Opinion on Drug Metabolism & Toxicology 2014; 10(8): 1079 doi: 10.1517/17425255.2014.925878
|
41 |
Matthias Ruopp, Sha Zhu, Rafael Worschech, Dorothee Haas, Simone Maschauer, Olaf Prante, Lorenz Meinel, Tessa Lühmann. Bioconjugation of a Fibroblast Activation Protein Targeted Interleukin-4. ACS Biomaterials Science & Engineering 2023; 9(10): 5580 doi: 10.1021/acsbiomaterials.3c00879
|
42 |
Xiaotian Zhong, Jill F. Wright. Biological Insights into Therapeutic Protein Modifications throughout Trafficking and Their Biopharmaceutical Applications. International Journal of Cell Biology 2013; 2013: 1 doi: 10.1155/2013/273086
|
43 |
Denise M O’Hara, Valerie Theobald. Life Cycle Management of Critical Ligand-Binding Reagents. Bioanalysis 2013; 5(21): 2679 doi: 10.4155/bio.13.241
|
44 |
Yulia Vugmeyster, Yiqun (Etran) Zhang, Xiaotian Zhong, Jill Wright, Sheldon S. Leung. Pharmacokinetics of anti-IL17A and anti-IL22 peptide–antibody bispecific genetic fusions in mice. International Immunopharmacology 2014; 18(2): 225 doi: 10.1016/j.intimp.2013.11.013
|
45 |
Liang Jin, Qi (Tony) Zhou, Hak-Kim Chan, Ian C. Larson, Michael W. Pennington, Rodrigo A.V. Morales, Ben J. Boyd, Raymond S. Norton, Joseph A. Nicolazzo. Pulmonary Delivery of the Kv1.3-Blocking Peptide HsTX1[R14A] for the Treatment of Autoimmune Diseases. Journal of Pharmaceutical Sciences 2016; 105(2): 650 doi: 10.1016/j.xphs.2015.10.025
|
46 |
Rafaela Malta, Ana Camila Marques, Paulo Cardoso da Costa, Maria Helena Amaral. Stimuli-Responsive Hydrogels for Protein Delivery. Gels 2023; 9(10): 802 doi: 10.3390/gels9100802
|
47 |
Alexander Bujotzek, Georg Tiefenthaler, Laurent Lariviere, Laura D’Andrea, Elsa A. Marquez, Ina Rudloff, Steven X. Cho, Nadia S. Deen, Wolfgang Richter, Franziska Regenass-Lechner, Alexander Poehler, James C. Whisstock, Jasmin Sydow-Andersen, Xaver Reiser, Sabine Schuster, Jeannette Neubauer, Sebastian Hoepfl, Kirsten Richter, Marcel F. Nold, Claudia A. Nold-Petry, Felix Schumacher, Andrew M. Ellisdon. Protein engineering of a stable and potent anti-inflammatory IL-37-Fc fusion with enhanced therapeutic potential. Cell Chemical Biology 2022; 29(4): 586 doi: 10.1016/j.chembiol.2021.10.004
|
48 |
Andreas Stahl, Noriyuki Azuma, Wei-Chi Wu, Domenico Lepore, Emine Sukgen, Hidehiko Nakanishi, Jan Mazela, Sergio Leal, Alexander Pieper, Sarah Schlief, Thomas Eissing, Kenneth C. Turner, An Zhao, Julia Winkler, Joachim Höchel, Evra Köfüncü, Torsten Zimmermann. Systemic exposure to aflibercept after intravitreal injection in premature neonates with retinopathy of prematurity: results from the FIREFLEYE randomized phase 3 study. Eye 2024; 38(8): 1444 doi: 10.1038/s41433-023-02919-9
|
49 |
Chee M. Ng. Incorporation of FcRn‐mediated disposition model to describe the population pharmacokinetics of therapeutic monoclonal IgG antibody in clinical patients. Biopharmaceutics & Drug Disposition 2016; 37(2): 107 doi: 10.1002/bdd.1997
|
50 |
Jie An, M. Saeed Sheikh. Toxicology of Trastuzumab: An Insight into Mechanisms of Cardiotoxicity. Current Cancer Drug Targets 2019; 19(5): 400 doi: 10.2174/1568009618666171129222159
|
51 |
Katherine L. Gill, Krishna K. Machavaram, Rachel H. Rose, Manoranjenni Chetty. Potential Sources of Inter-Subject Variability in Monoclonal Antibody Pharmacokinetics. Clinical Pharmacokinetics 2016; 55(7): 789 doi: 10.1007/s40262-015-0361-4
|
52 |
|
53 |
Sven Kronenberg, Andreas Baumann, Lolke de Haan, Heather J. Hinton, Jonathan Moggs, Frank-Peter Theil, Ian Wakefield, Thomas Singer. Current challenges and opportunities in nonclinical safety testing of biologics. Drug Discovery Today 2013; 18(23-24): 1138 doi: 10.1016/j.drudis.2013.08.003
|
54 |
Pauline L. Martin. Principles of Safety Pharmacology. Handbook of Experimental Pharmacology 2015; 229: 405 doi: 10.1007/978-3-662-46943-9_16
|
55 |
Nouran Farid, Aibobek Seitak, Vincent Chan, Sungmun Lee. Alginate-Based Oral Delivery Systems to Enhance Protection, Release, and Absorption of Catalase. ACS Biomaterials Science & Engineering 2023; 9(6): 3390 doi: 10.1021/acsbiomaterials.3c00278
|
56 |
Peng Zou, Sau Lee, Min Li, Lawrence Yu, Duxin Sun. Pharmacokinetics in Drug Development. 2016; : 39 doi: 10.1007/978-3-319-39053-6_3
|
57 |
Brian J Geist, Adrienne Clements Egan, Tong-Yuan Yang, Yuxin Dong, Gopi Shankar. Characterization of Critical Reagents in Ligand-Binding Assays: Enabling Robust Bioanalytical Methods and Lifecycle Management. Bioanalysis 2013; 5(2): 227 doi: 10.4155/bio.12.304
|
58 |
Xing Jing, Yan Hou, William Hallett, Chandrahas G. Sahajwalla, Ping Ji. Therapeutic Enzymes: Function and Clinical Implications. Advances in Experimental Medicine and Biology 2019; 1148: 115 doi: 10.1007/978-981-13-7709-9_6
|
59 |
Sukumar Hariharan, Shashimohan Keelara, Vivek Daniel Paul, Bharathi Sriram, Aradhana Amin Vipra, Tanjore Balganesh. Drug Discovery Targeting Drug-Resistant Bacteria. 2020; : 301 doi: 10.1016/B978-0-12-818480-6.00011-4
|
60 |
Yuwei Deng, Li Hu, Wei Qiang, Zeneng Cheng, Lei Wang, Xiaoxia Wang. TNF‐α level affects etanercept clearance: TNF‐α concentration as a new correction factor of allometric scaling to predict individual etanercept clearances in patients with ankylosing spondylitis. Clinical and Experimental Pharmacology and Physiology 2018; 45(7): 643 doi: 10.1111/1440-1681.12924
|
61 |
Lei He, Donglin Feng, Hui Guo, Yueyuan Zhou, Zhaozhao Li, Kuo Zhang, Wangqian Zhang, Shuning Wang, Zhaowei Wang, Qiang Hao, Cun Zhang, Yuan Gao, Jintao Gu, Yingqi Zhang, Weina Li, Meng Li. Pharmacokinetics, distribution, metabolism, and excretion of body-protective compound 157, a potential drug for treating various wounds, in rats and dogs. Frontiers in Pharmacology 2022; 13 doi: 10.3389/fphar.2022.1026182
|
62 |
A. M. Ryan. Frontiers in Nonclinical Drug Development. Veterinary Pathology 2015; 52(2): 419 doi: 10.1177/0300985814547282
|
63 |
Y.J. Bang, G. Giaccone, S.A. Im, D.Y. Oh, T.M. Bauer, J.L. Nordstrom, H. Li, G.R. Chichili, P.A. Moore, S. Hong, S.J. Stewart, J.E. Baughman, R.J. Lechleider, H.A. Burris. First-in-human phase 1 study of margetuximab (MGAH22), an Fc-modified chimeric monoclonal antibody, in patients with HER2-positive advanced solid tumors. Annals of Oncology 2017; 28(4): 855 doi: 10.1093/annonc/mdx002
|
64 |
Martin Klinger. A role for macromolecular crowding in off-target binding of therapeutic antibodies. Protein Engineering, Design and Selection 2017; 30(7): 489 doi: 10.1093/protein/gzx035
|
65 |
Mahdie Rahban, Faizan Ahmad, Mieczyslaw A. Piatyszek, Thomas Haertlé, Luciano Saso, Ali Akbar Saboury. Stabilization challenges and aggregation in protein-based therapeutics in the pharmaceutical industry. RSC Advances 2023; 13(51): 35947 doi: 10.1039/D3RA06476J
|
66 |
Mattia D’Agostino, Giulia Gazzera, Giusy Cetani, Sara Bringhen, Mario Boccadoro, Francesca Gay. Clinical and Pharmacologic Features of Monoclonal Antibodies and Checkpoint Blockade Therapy in Multiple Myeloma. Current Medicinal Chemistry 2019; 26(32): 5968 doi: 10.2174/0929867325666180514114806
|
67 |
Galina Obmolova, Alexey Teplyakov, Thomas J. Malia, Nicole Wunderler, Deborah Kwok, Linda Barone, Raymond Sweet, Tatiana Ort, Michael Scully, Gary L. Gilliland. Epitope-dependent mechanisms of CD27 neutralization revealed by X-ray crystallography. Molecular Immunology 2017; 83: 92 doi: 10.1016/j.molimm.2017.01.005
|
68 |
Ningning Xu, Meimei Liu, Margaret Liu. Biosimilars of Monoclonal Antibodies. 2016; : 201 doi: 10.1002/9781118940648.ch6
|
69 |
Akshay Jain, Ashutosh Barve, Zhen Zhao, Wei Jin, Kun Cheng. Comparison of Avidin, Neutravidin, and Streptavidin as Nanocarriers for Efficient siRNA Delivery. Molecular Pharmaceutics 2017; 14(5): 1517 doi: 10.1021/acs.molpharmaceut.6b00933
|
70 |
W.U. Benjamin, Yu-Nien Sun. Pharmacokinetics of Peptide–Fc Fusion Proteins. Journal of Pharmaceutical Sciences 2014; 103(1): 53 doi: 10.1002/jps.23783
|
71 |
Imran Ozer, Garrett Kelly, Renpeng Gu, Xinghai Li, Nikita Zakharov, Parul Sirohi, Smita K. Nair, Joel H. Collier, Michael S. Hershfield, Angus M. Hucknall, Ashutosh Chilkoti. Polyethylene Glycol‐Like Brush Polymer Conjugate of a Protein Drug Does Not Induce an Antipolymer Immune Response and Has Enhanced Pharmacokinetics than Its Polyethylene Glycol Counterpart. Advanced Science 2022; 9(11) doi: 10.1002/advs.202103672
|
72 |
Jennifer A. Schwartz, Ilia Prado, Johnathan Misamore, Deborah Weiss, Jesse Francis, Ranajit Pal, Maria Huaman, Anthony Cristillo, George K. Lewis, Robert C. Gallo, Anthony L. DeVico, Timothy R. Fouts, H. F. Staats. An HIV gp120-CD4 Immunogen Does Not Elicit Autoimmune Antibody Responses in Cynomolgus Macaques. Clinical and Vaccine Immunology 2016; 23(7): 618 doi: 10.1128/CVI.00115-16
|
73 |
Renu Chaudhary, Meenakshi Balhara, Anil Kumar Chhillar. Metabolic Engineering for Bioactive Compounds. 2017; : 73 doi: 10.1007/978-981-10-5511-9_4
|
74 |
Jianing Zeng, Hao Jiang, Linlin Luo. Protein Analysis using Mass Spectrometry. 2017; : 91 doi: 10.1002/9781119371779.ch8
|
75 |
Seong Min Choi, Ju-Hee Lee, Soyeon Ko, Soon-Sun Hong, Hyo-Eon Jin. Mechanism of Action and Pharmacokinetics of Approved Bispecific Antibodies. Biomolecules & Therapeutics 2024; 32(6): 708 doi: 10.4062/biomolther.2024.146
|
76 |
Syed Faaiz Enam, Jack R. Krieger, Tarun Saxena, Brian E. Watts, Claire E. Olingy, Edward A. Botchwey, Ravi V. Bellamkonda. Enrichment of endogenous fractalkine and anti-inflammatory cells via aptamer-functionalized hydrogels. Biomaterials 2017; 142: 52 doi: 10.1016/j.biomaterials.2017.07.013
|
77 |
Hoi-Kei Lon, Dongyang Liu, Debra C. DuBois, Richard R. Almon, William J. Jusko. Modeling pharmacokinetics/pharmacodynamics of abatacept and disease progression in collagen-induced arthritic rats: a population approach. Journal of Pharmacokinetics and Pharmacodynamics 2013; 40(6): 701 doi: 10.1007/s10928-013-9341-1
|
78 |
Lei Wang, Shan Ji, Meizhen Li, Zeneng Cheng. A novel pharmacokinetic model based on the complex elimination of monoclonal antibodies for bevacizumab pharmacokinetic study in rabbits. International Immunopharmacology 2016; 31: 39 doi: 10.1016/j.intimp.2015.12.016
|
79 |
Youssef Hijazi. Prediction of Half-Life Extension of Peptides via Serum Albumin Binding: Current Challenges. European Journal of Drug Metabolism and Pharmacokinetics 2021; 46(2): 163 doi: 10.1007/s13318-020-00664-y
|
80 |
Sarfaraz K. Niazi. Molecular Biosimilarity—An AI-Driven Paradigm Shift. International Journal of Molecular Sciences 2022; 23(18): 10690 doi: 10.3390/ijms231810690
|
81 |
Neeraj Mittal, Gajanand Sharma, Om Parkash Katare, Sanjay Kumar Bhadada.
A Narrative Review on Non-Invasive Drug Delivery of Teriparatide: A Ray of Hope
. Critical Reviews™ in Therapeutic Drug Carrier Systems 2023; 40(6): 117 doi: 10.1615/CritRevTherDrugCarrierSyst.2023045480
|
82 |
Ian Nessler, Cornelius Cilliers, Greg M. Thurber. Practical Guide for Quantification of In Vivo Degradation Rates for Therapeutic Proteins with Single-Cell Resolution Using Fluorescence Ratio Imaging. Pharmaceutics 2020; 12(2): 132 doi: 10.3390/pharmaceutics12020132
|
83 |
James T Heads, Richard Lamb, Sebastian Kelm, Ralph Adams, Peter Elliott, Kerry Tyson, Sarfaraj Topia, Shauna West, Ruodan Nan, Alison Turner, Alastair D G Lawson. Electrostatic interactions modulate the differential aggregation propensities of IgG1 and IgG4P antibodies and inform charged residue substitutions for improved developability. Protein Engineering, Design and Selection 2019; 32(6): 277 doi: 10.1093/protein/gzz046
|
84 |
Heng-Keang Lim, Yuan Cao, Xi Qiu, Jose Silva, David C Evans. A Nonradioactive Approach to Investigate the Metabolism of Therapeutic Peptides by Tagging with 127I and Using Inductively-Coupled Plasma Mass Spectrometry Analysis. Drug Metabolism and Disposition 2015; 43(1): 17 doi: 10.1124/dmd.114.059774
|
85 |
Matthew McMaster, Kelly Mohr, Austin Page, Adam Closmore, Francina Towne, Benjamin D. Brooks. Epitope characterization of anti-drug antibodies—a tool for discovery and health: an overview of the necessity of early epitope characterization to avoid anti-drug antibodies and promote patient health. Expert Opinion on Biological Therapy 2021; 21(6): 705 doi: 10.1080/14712598.2021.1863942
|
86 |
Youssef Hijazi. Utility of in silico prediction of target suppression for antibodies against soluble targets: static versus dynamic models. European Journal of Clinical Pharmacology 2023; 79(1): 137 doi: 10.1007/s00228-022-03425-9
|
87 |
Yoshiya Tanaka, Toshiya Takahashi, Mariko Sumi, Owen Hagino, Hubert Van Hoogstraten, Christine Xu, Naoto Kato, Hideto Kameda. Immunogenicity of sarilumab and impact on safety and efficacy in Japanese patients with rheumatoid arthritis: analysis of two Phase 3 randomised clinical trials. Modern Rheumatology 2022; 32(4): 686 doi: 10.1093/mr/roab066
|
88 |
Rajesh Pradhan, Meghna Pandey, Siddhanth Hejmady, Rajeev Taliyan, Gautam Singhvi, Sunil K. Dubey, Sachin Dubey. Targeted Drug Delivery. Methods and Principles in Medicinal Chemistry 2022; : 127 doi: 10.1002/9783527827855.ch5
|
89 |
Josh T Pearson, Dan A Rock. Bioanalytical Approaches to Assess The Proteolytic Stability of Therapeutic Fusion Proteins. Bioanalysis 2015; 7(23): 3035 doi: 10.4155/bio.15.217
|
90 |
Miroslav Dostalek, Thomayant Prueksaritanont, Robert F. Kelley. Pharmacokinetic de-risking tools for selection of monoclonal antibody lead candidates. mAbs 2017; 9(5): 756 doi: 10.1080/19420862.2017.1323160
|
91 |
Kenta Haraya, Tatsuhiko Tachibana, Tomoyuki Igawa. Improvement of pharmacokinetic properties of therapeutic antibodies by antibody engineering. Drug Metabolism and Pharmacokinetics 2019; 34(1): 25 doi: 10.1016/j.dmpk.2018.10.003
|
92 |
Brian J. Schmidt, Chin Pan, Heather E. Vezina, Huadong Sun, Douglas D. Leipold, Manish Gupta. Antibody‐Drug Conjugates. 2016; : 207 doi: 10.1002/9781119060727.ch9
|
93 |
Uma Fogueri, Wisit Cheungapasitporn, David Bourne, Fernando C. Fervenza, Melanie S. Joy. Rituximab Exhibits Altered Pharmacokinetics in Patients With Membranous Nephropathy. Annals of Pharmacotherapy 2019; 53(4): 357 doi: 10.1177/1060028018803587
|
94 |
S. E. Kuyooro, J. K. Akintunde, F. C. Okekearu, E. N. Maduagwu. Toxicokinetics and Biliary Excretion of N-Nitrosodiethylamine in Rat Supplemented with Low and High Dietary Proteins. Journal of Dietary Supplements 2019; 16(5): 506 doi: 10.1080/19390211.2018.1471561
|
95 |
Richard J. D. Hatley, Simon J. F. Macdonald, Robert J. Slack, Joelle Le, Steven B. Ludbrook, Pauline T. Lukey. Ein Instrumentarium von αv‐RGD‐Integrin‐Inhibitoren: Wirkstoffsuche, Herausforderungen und Möglichkeiten. Angewandte Chemie 2018; 130(13): 3354 doi: 10.1002/ange.201707948
|
96 |
Sankha Bhattacharya, Paul Rodriques, Bhupendra Prajapati. Advanced Drug Delivery Systems. 2023; doi: 10.5772/intechopen.109337
|
97 |
Erez M. Bublil, Tomas Majtan, Insun Park, Richard S. Carrillo, Helena Hůlková, Jakub Krijt, Viktor Kožich, Jan P. Kraus. Enzyme replacement with PEGylated cystathionine β-synthase ameliorates homocystinuria in murine model. Journal of Clinical Investigation 2016; 126(6): 2372 doi: 10.1172/JCI85396
|
98 |
Remko van Vught, Roland J Pieters, Eefjan Breukink. SITE-SPECIFIC FUNCTIONALIZATION OF PROTEINS AND THEIR APPLICATIONS TO THERAPEUTIC ANTIBODIES. Computational and Structural Biotechnology Journal 2014; 9(14): e201402001 doi: 10.5936/csbj.201402001
|
99 |
Daniel Schweizer, Tim Serno, Achim Goepferich. Controlled release of therapeutic antibody formats. European Journal of Pharmaceutics and Biopharmaceutics 2014; 88(2): 291 doi: 10.1016/j.ejpb.2014.08.001
|
100 |
Ninad Varkhede, Rupesh Bommana, Christian Schöneich, M. Laird Forrest. Proteolysis and Oxidation of Therapeutic Proteins After Intradermal or Subcutaneous Administration. Journal of Pharmaceutical Sciences 2020; 109(1): 191 doi: 10.1016/j.xphs.2019.08.005
|
101 |
Amanda J. Bischoff, Conner C. Harper, Evan R. Williams, Matthew B. Francis. Characterizing Heterogeneous Mixtures of Assembled States of the Tobacco Mosaic Virus Using Charge Detection Mass Spectrometry. Journal of the American Chemical Society 2022; 144(51): 23368 doi: 10.1021/jacs.2c09160
|
102 |
Elena A. Morozova, Vitalia V. Kulikova, Natalya V. Anufrieva, Alexey N. Minakov, Alexandr S. Chernov, Georgij B. Telegin, Svetlana V. Revtovich, Vasily S. Koval, Tatyana V. Demidkina. Methionine γ-lyase in enzyme prodrug therapy: An improvement of pharmacokinetic parameters of the enzyme. International Journal of Biological Macromolecules 2019; 140: 1277 doi: 10.1016/j.ijbiomac.2019.08.224
|
103 |
Krithika A. Shetty, Matthew P. Kosloski, Donald E. Mager, Sathy V. Balu‐Iyer. Factor VIII associated with lipidic nanoparticles retains efficacy in the presence of anti‐factor VIII antibodies in hemophilia A mice. Biopharmaceutics & Drug Disposition 2016; 37(7): 409 doi: 10.1002/bdd.2023
|
104 |
T. Laomettachit, I.K. Puri, M. Liangruksa. A two-step model of TiO 2 nanoparticle toxicity in human liver tissue. Toxicology and Applied Pharmacology 2017; 334: 47 doi: 10.1016/j.taap.2017.08.018
|
105 |
Sandor Kerpel-Fronius. A short review of the pharmacokinetic behavior of biological medicinal agents for the clinical practice. Microchemical Journal 2018; 136: 270 doi: 10.1016/j.microc.2017.05.005
|
106 |
Sahar Awwad, Athmar Al‐Shohani, Peng T. Khaw, Steve Brocchini. Comparative Study of In Situ Loaded Antibody and PEG‐Fab NIPAAM Gels. Macromolecular Bioscience 2018; 18(2) doi: 10.1002/mabi.201700255
|
107 |
Aman Chandra Kaushik, Yan-Jing Wang, Xiangeng Wang, Ajay Kumar, Satya P. Singh, Cheng-Tang Pan, Yow-Ling Shiue, Dong-Qing Wei. Evaluation of anti-EGFR-iRGD recombinant protein with GOLD nanoparticles: synergistic effect on antitumor efficiency using optimized deep neural networks. RSC Advances 2019; 9(34): 19261 doi: 10.1039/C9RA01975H
|
108 |
V. Ashutosh Rao. Biobetters. AAPS Advances in the Pharmaceutical Sciences Series 2015; 19: 183 doi: 10.1007/978-1-4939-2543-8_11
|
109 |
Mari R. Thomas, Rens de Groot, Marie A. Scully, James T.B. Crawley. Pathogenicity of Anti-ADAMTS13 Autoantibodies in Acquired Thrombotic Thrombocytopenic Purpura. EBioMedicine 2015; 2(8): 942 doi: 10.1016/j.ebiom.2015.06.007
|
110 |
Tori Czech, Moses O. Oyewumi. Overcoming barriers confronting application of protein therapeutics in bone fracture healing. Drug Delivery and Translational Research 2021; 11(3): 842 doi: 10.1007/s13346-020-00829-x
|
111 |
Natalia Porębska, Krzysztof Ciura, Aleksandra Chorążewska, Małgorzata Zakrzewska, Jacek Otlewski, Łukasz Opaliński. Multivalent protein-drug conjugates – An emerging strategy for the upgraded precision and efficiency of drug delivery to cancer cells. Biotechnology Advances 2023; 67: 108213 doi: 10.1016/j.biotechadv.2023.108213
|
112 |
Aleksandra Szwed-Georgiou, Przemysław Płociński, Barbara Kupikowska-Stobba, Mateusz M. Urbaniak, Paulina Rusek-Wala, Konrad Szustakiewicz, Paweł Piszko, Agnieszka Krupa, Monika Biernat, Małgorzata Gazińska, Mirosław Kasprzak, Katarzyna Nawrotek, Nuno Pereira Mira, Karolina Rudnicka. Bioactive Materials for Bone Regeneration: Biomolecules and Delivery Systems. ACS Biomaterials Science & Engineering 2023; 9(9): 5222 doi: 10.1021/acsbiomaterials.3c00609
|
113 |
Christopher J Bowman, Robert E Chapin. Goldilocks’ Determination of What New In Vivo Data are “Just Right” for Different Common Drug Development Scenarios, Part 1. Birth Defects Research Part B: Developmental and Reproductive Toxicology 2016; 107(4-5): 185 doi: 10.1002/bdrb.21184
|
114 |
Jamie B. Strachan, Brendan P. Dyett, Zeyad Nasa, Celine Valery, Charlotte E. Conn. Toxicity and cellular uptake of lipid nanoparticles of different structure and composition. Journal of Colloid and Interface Science 2020; 576: 241 doi: 10.1016/j.jcis.2020.05.002
|
115 |
Robin Rajan, Tadaomi Furuta, Dandan Zhao, Kazuaki Matsumura. Molecular mechanism of protein aggregation inhibition with sulfobetaine polymers and their hydrophobic derivatives. Cell Reports Physical Science 2024; 5(6): 102012 doi: 10.1016/j.xcrp.2024.102012
|
116 |
Noritaka HASHII, Masahiro UTOH, Yoshiaki OHTSU, Nozomu KATO, Ryoya GODA, Rieko GOTO, Hisao SHIMIZU, Fujiko TAKAMURA, Masaki HOSHINO, Masanari MABUCHI, Takeru YAMAGUCHI, Akiko ISHII-WATABE, Noriko KATORI. Bioanalytical Quantification of Therapeutic Antibodies by Liquid Chromatography/mass Spectrometry. CHROMATOGRAPHY 2018; 39(1): 7 doi: 10.15583/jpchrom.2017.018
|
117 |
Nicole L. Jarvi, Sathy V. Balu-Iyer. Immunogenicity Challenges Associated with Subcutaneous Delivery of Therapeutic Proteins. BioDrugs 2021; 35(2): 125 doi: 10.1007/s40259-020-00465-4
|
118 |
Minati Nayak, Ram Pada Das, Liladhar B. Kumbhare, Beena G. Singh, Michio Iwaoka, Amit Kunwar. Diseleno-albumin, a native bio-inspired drug free therapeutic protein induces apoptosis in lung cancer cells through mitochondrial oxidation. International Journal of Biological Macromolecules 2024; 279: 135141 doi: 10.1016/j.ijbiomac.2024.135141
|
119 |
Martin Schwickart, Inna Vainshtein, Rozanne Lee, Amy Schneider, Meina Liang. Interference in Immunoassays to Support Therapeutic Antibody Development in Preclinical and Clinical Studies. Bioanalysis 2014; 6(14): 1939 doi: 10.4155/bio.14.127
|
120 |
Li Sun, Yang Xu, Neal Dube, Melanie Anderson, Sheila Breidinger, Pavan Vaddady, Bob Thornton, Linda Morrow, Randolph P. Matthews, S. Aubrey Stoch, Eric J. Woolf. Incorporating protein precipitation to resolve hybrid IP-LC-MS assay interference for ultrasensitive quantification of intact therapeutic insulin dimer in human plasma. Journal of Pharmaceutical and Biomedical Analysis 2022; 212: 114639 doi: 10.1016/j.jpba.2022.114639
|
121 |
Daniela Silva-Adaya, Carla Garza-Lombó, María E. Gonsebatt. Xenobiotic transport and metabolism in the human brain. NeuroToxicology 2021; 86: 125 doi: 10.1016/j.neuro.2021.08.004
|
122 |
Kei Sakamoto, Shunji Matsuki, Shin Irie, Naoki Uchida, Nobuya Hayashi, Masato Horiuchi, Song Ren. A Phase 1, Randomized, Placebo‐Controlled Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of Subcutaneous Tezepelumab in Healthy Japanese Men. Clinical Pharmacology in Drug Development 2020; 9(7): 833 doi: 10.1002/cpdd.775
|
123 |
Stephanny Miranda Alves de Souza, Blanca Hernández-Ledesma, Theo Luiz Ferraz de Souza. Lunasin as a Promising Plant-Derived Peptide for Cancer Therapy. International Journal of Molecular Sciences 2022; 23(17): 9548 doi: 10.3390/ijms23179548
|
124 |
Roshni Rao, Daniela Verthelyi. The Science and Regulations of Naturally Derived Complex Drugs. AAPS Advances in the Pharmaceutical Sciences Series 2019; 32: 219 doi: 10.1007/978-3-030-11751-1_13
|
125 |
Sara Hosseininasab, Roghiyeh Pashaei‐Asl, Amir Ahmad Khandaghi, Hamid Tayefi Nasrabadi, Kazem Nejati‐Koshki, Abolfazl Akbarzadeh, Sang Woo Joo, Younes Hanifehpour, Soodabeh Davaran. Retracted: Synthesis, Characterization, and In vitro Studies of PLGA–PEG Nanoparticles for Oral Insulin Delivery. Chemical Biology & Drug Design 2014; 84(3): 307 doi: 10.1111/cbdd.12318
|
126 |
Robert S. Foti, Kaustav Biswas, Jennifer Aral, Xuhai Be, Loren Berry, Yuan Cheng, Kip Conner, James R. Falsey, Charles Glaus, Brad Herberich, Dean Hickman, Tayo Ikotun, Hongyan Li, Jason Long, Liyue Huang, Les P. Miranda, Justin Murray, Bryan Moyer, Chawita Netirojjanakul, Thomas E. Nixey, Kelvin Sham, Marcus Soto, Christopher M. Tegley, Linh Tran, Bin Wu, Lin Yin, Dan A. Rock. Use of Cryopreserved Hepatocytes as Part of an Integrated Strategy to Characterize In Vivo Clearance for Peptide-Antibody Conjugate Inhibitors of Nav1.7 in Preclinical Species. Drug Metabolism and Disposition 2019; 47(10): 1111 doi: 10.1124/dmd.119.087742
|
127 |
Martin Schwickart, Freshta Mehrzai, Jennifer Pearson, Nabila Shaghasi, Carlos Chavez, Amy Schneider, Spencer Wu, Lorin Roskos, Meina Liang. Identification and elimination of target-related matrix interference in a neutralizing anti-drug antibody assay. Journal of Immunological Methods 2014; 403(1-2): 52 doi: 10.1016/j.jim.2013.11.018
|
128 |
|
129 |
Varun Ramani, Sanjeev Bhardwaj, Omnia A. Ismaiel. An Introduction to Bioanalysis of Biopharmaceuticals. AAPS Advances in the Pharmaceutical Sciences Series 2022; 57: 19 doi: 10.1007/978-3-030-97193-9_2
|
130 |
Frank A. Engler, Bo Zheng, Joseph P. Balthasar. Investigation of the Influence of Nephropathy on Monoclonal Antibody Disposition: A Pharmacokinetic Study in a Mouse Model of Diabetic Nephropathy. Pharmaceutical Research 2014; 31(5): 1185 doi: 10.1007/s11095-013-1241-y
|
131 |
Barbara Kupikowska-Stobba, Marcin Grzeczkowicz, Dorota Lewińska. A one-step in vitro continuous flow assessment of protein release from core-shell polymer microcapsules designed for therapeutic protein delivery. Biocybernetics and Biomedical Engineering 2021; 41(4): 1347 doi: 10.1016/j.bbe.2021.05.003
|
132 |
Carla Biesdorf, Xiaowen Guan, Satya R. Siddani, David Hoffman, Nils Boehm, Bruno C. Medeiros, Toshihiko Doi, Maja de Jonge, Drew Rasco, Rajeev M. Menon, Akshanth R. Polepally. Pharmacokinetics and immunogenicity of eftozanermin alfa in subjects with previously-treated solid tumors or hematologic malignancies: results from a phase 1 first-in-human study. Cancer Chemotherapy and Pharmacology 2024; 93(4): 329 doi: 10.1007/s00280-023-04613-9
|
133 |
Brian Gurbaxani, Miroslav Dostalek, Iain Gardner. Are endosomal trafficking parameters better targets for improving mAb pharmacokinetics than FcRn binding affinity?. Molecular Immunology 2013; 56(4): 660 doi: 10.1016/j.molimm.2013.05.008
|
134 |
Pankajini Mallick, Guncha Taneja, Bhagavatula Moorthy, Romi Ghose. Regulation of drug-metabolizing enzymes in infectious and inflammatory disease: implications for biologics–small molecule drug interactions. Expert Opinion on Drug Metabolism & Toxicology 2017; 13(6): 605 doi: 10.1080/17425255.2017.1292251
|
135 |
Syed Faaiz Enam, Sajidur Rahman Kader, Nicholas Bodkin, Johnathan G. Lyon, Mark Calhoun, Cesar Azrak, Pooja Munnilal Tiwari, Daryll Vanover, Haichen Wang, Philip J. Santangelo, Ravi Venkat Bellamkonda. Evaluation of M2-like macrophage enrichment after diffuse traumatic brain injury through transient interleukin-4 expression from engineered mesenchymal stromal cells. Journal of Neuroinflammation 2020; 17(1) doi: 10.1186/s12974-020-01860-y
|
136 |
Saurabh Patil, Aditya Narvekar, Amita Puranik, Ratnesh Jain, Prajakta Dandekar. Innovative Dosage Forms. Methods and Principles in Medicinal Chemistry 2019; : 391 doi: 10.1002/9783527812172.ch12
|
137 |
Jiunn H. Lin, Weirong Wang. Pharmaceutical Sciences Encyclopedia. 2015; : 1 doi: 10.1002/9780470571224.pse541
|
138 |
Yun Seob Jung, Dongwoo Chae, Kyungsoo Park. Population PK-PD Model of Pegylated Interferon Alfa-2a in Healthy Korean Men. Journal of Pharmaceutical Sciences 2018; 107(12): 3171 doi: 10.1016/j.xphs.2018.08.017
|
139 |
Linda J. Chan, Jürgen B. Bulitta, David B. Ascher, John M. Haynes, Victoria M. McLeod, Christopher J. H. Porter, Charlotte C. Williams, Lisa M. Kaminskas. PEGylation Does Not Significantly Change the Initial Intravenous or Subcutaneous Pharmacokinetics or Lymphatic Exposure of Trastuzumab in Rats but Increases Plasma Clearance after Subcutaneous Administration. Molecular Pharmaceutics 2015; 12(3): 794 doi: 10.1021/mp5006189
|
140 |
Paul J. Carter, Greg A. Lazar. Next generation antibody drugs: pursuit of the 'high-hanging fruit'. Nature Reviews Drug Discovery 2018; 17(3): 197 doi: 10.1038/nrd.2017.227
|
141 |
Joel P. Bercu, Eric J. Morinello, Claudia Sehner, Bryan K. Shipp, Patricia A. Weideman. Point of departure (PoD) selection for the derivation of acceptable daily exposures (ADEs) for active pharmaceutical ingredients (APIs). Regulatory Toxicology and Pharmacology 2016; 79: S48 doi: 10.1016/j.yrtph.2016.05.028
|
142 |
Aaron C. Anselmo, Yatin Gokarn, Samir Mitragotri. Non-invasive delivery strategies for biologics. Nature Reviews Drug Discovery 2019; 18(1): 19 doi: 10.1038/nrd.2018.183
|
143 |
Monika Weber, Jason M. Criscione, Xuexin Duan, Tarek M. Fahmy, Jason Park, Nitin K. Rajan, David A. Routenberg, Erin Steenblock, Eric Stern, Aleksandar Vacic, Mark A. Reed. Handbook of Bioelectronics. 2015; : 122 doi: 10.1017/CBO9781139629539.012
|
144 |
Warren D. Harvey. Drug Discovery and Evaluation: Safety and Pharmacokinetic Assays. 2023; : 1 doi: 10.1007/978-3-030-73317-9_133-1
|
145 |
Warren D. Harvey. Drug Discovery and Evaluation: Safety and Pharmacokinetic Assays. 2024; : 2271 doi: 10.1007/978-3-031-35529-5_133
|
146 |
Malcolm A. Young, Jeffrey A. Wald, Jessica E. Matthews, Rhona Scott, Rebecca J. Hodge, Hui Zhi, Rickey R. Reinhardt. Clinical Pharmacology of Albiglutide, a GLP-1 Receptor Agonist. Postgraduate Medicine 2014; 126(7): 84 doi: 10.3810/pgm.2014.11.2836
|
147 |
Mita Kuchimanchi, Anita Grover, Maurice G. Emery, Ransi Somaratne, Scott M. Wasserman, John P. Gibbs, Sameer Doshi. Population pharmacokinetics and exposure–response modeling and simulation for evolocumab in healthy volunteers and patients with hypercholesterolemia. Journal of Pharmacokinetics and Pharmacodynamics 2018; 45(3): 505 doi: 10.1007/s10928-018-9592-y
|
148 |
Ashok Kumar, Gopal Das, Biplab Bose. Recombinant Receptor-Binding Domain of Diphtheria Toxin Increases the Potency of Curcumin by Enhancing Cellular Uptake. Molecular Pharmaceutics 2014; 11(1): 208 doi: 10.1021/mp400378x
|
149 |
Xin Xu, Yulia Vugmeyster. Challenges and Opportunities in Absorption, Distribution, Metabolism, and Excretion Studies of Therapeutic Biologics. The AAPS Journal 2012; 14(4): 781 doi: 10.1208/s12248-012-9388-8
|
150 |
Xiangdan Wang, Patrick McKay, Liliana T. Yee, George Dutina, Philip E. Hass, Ihsan Nijem, David Allison, Kyra J. Cowan, Kevin Lin, Valerie Quarmby, Jihong Yang. Impact of SPR biosensor assay configuration on antibody: Neonatal Fc receptor binding data. mAbs 2017; 9(2): 319 doi: 10.1080/19420862.2016.1261774
|
151 |
D Q Holt, P Varma, B J G Strauss, A S Rajadurai, G T Moore. Low muscle mass at initiation of anti-TNF therapy for inflammatory bowel disease is associated with early treatment failure: a retrospective analysis. European Journal of Clinical Nutrition 2017; 71(6): 773 doi: 10.1038/ejcn.2017.10
|
152 |
Magdalena J. Laska, Jesper Bonnet Moeller, Jonas Heilskov Graversen, Dorte Strøbæk, Linda Blomster, Palle Christophersen, Shervin Bahrami. Retroviral glycoprotein-mediated immune suppression via the potassium channel KCa3.1 – A new strategy for amelioration of inflammatory bowel diseases. Clinical Immunology 2022; 242: 109081 doi: 10.1016/j.clim.2022.109081
|
153 |
Yulia Vugmeyster, John Harrold, Xin Xu. Absorption, Distribution, Metabolism, and Excretion (ADME) Studies of Biotherapeutics for Autoimmune and Inflammatory Conditions. The AAPS Journal 2012; 14(4): 714 doi: 10.1208/s12248-012-9385-y
|
154 |
Marilena Hadjidemetriou, Sarah McAdam, Grace Garner, Chelsey Thackeray, David Knight, Duncan Smith, Zahraa Al‐Ahmady, Mariarosa Mazza, Jane Rogan, Andrew Clamp, Kostas Kostarelos. The Human In Vivo Biomolecule Corona onto PEGylated Liposomes: A Proof‐of‐Concept Clinical Study. Advanced Materials 2019; 31(4) doi: 10.1002/adma.201803335
|
155 |
Imran Ozer, Anna Slezak, Parul Sirohi, Xinghai Li, Nikita Zakharov, Yunxin Yao, Jeffrey I. Everitt, Ivan Spasojevic, Stephen L. Craig, Joel H. Collier, Jonathan E. Campbell, David A. D'Alessio, Ashutosh Chilkoti. An injectable PEG-like conjugate forms a subcutaneous depot and enables sustained delivery of a peptide drug. Biomaterials 2023; 294: 121985 doi: 10.1016/j.biomaterials.2022.121985
|
156 |
Terrence L. Fisher, Christine A. Reilly, Laurie A. Winter, Tracy Pandina, Alan Jonason, Maria Scrivens, Leslie Balch, Holm Bussler, Sebold Torno, Jennifer Seils, Loretta Mueller, He Huang, Ekaterina Klimatcheva, Alan Howell, Renee Kirk, Elizabeth Evans, Mark Paris, John E. Leonard, Ernest S. Smith, Maurice Zauderer. Generation and preclinical characterization of an antibody specific for SEMA4D. mAbs 2016; 8(1): 150 doi: 10.1080/19420862.2015.1102813
|
157 |
Yulia Vugmeyster, Clifford A. Entrican, Alison P. Joyce, Rosemary F. Lawrence-Henderson, Beth A. Leary, Christopher S. Mahoney, Himakshi K. Patel, Stephen W. Raso, Stephane H. Olland, Martin Hegen, Xin Xu. Pharmacokinetic, Biodistribution, and Biophysical Profiles of TNF Nanobodies Conjugated to Linear or Branched Poly(ethylene glycol). Bioconjugate Chemistry 2012; 23(7): 1452 doi: 10.1021/bc300066a
|
158 |
Alejandro Balsa, Raimon Sanmarti, José Rosas, Victor Martin, Ana Cabez, Susana Gómez, María Montoro. Drug immunogenicity in patients with inflammatory arthritis and secondary failure to tumour necrosis factor inhibitor therapies: the REASON study. Rheumatology 2018; 57(4): 688 doi: 10.1093/rheumatology/kex474
|
159 |
A. R. Satvik Iyengar, Shreya Gupta, Snehal Jawalekar, Abhay H. Pande. Protein Chimerization: A New Frontier for Engineering Protein Therapeutics with Improved Pharmacokinetics. The Journal of Pharmacology and Experimental Therapeutics 2019; 370(3): 703 doi: 10.1124/jpet.119.257063
|
160 |
Janet Gould, Courtney M. Callis, David G. Dolan, Brad Stanard, Patricia A. Weideman. Special endpoint and product specific considerations in pharmaceutical acceptable daily exposure derivation. Regulatory Toxicology and Pharmacology 2016; 79: S79 doi: 10.1016/j.yrtph.2016.05.022
|
161 |
Lineth Juliana Vega-Rojas, Ivan Luzardo-Ocampo, Juan Mosqueda, Dulce María Palmerín-Carreño, Antonio Escobedo-Reyes, Alejandro Blanco-Labra, Konisgmar Escobar-García, Teresa García-Gasca. Bioaccessibility and In Vitro Intestinal Permeability of a Recombinant Lectin from Tepary Bean (Phaseolus acutifolius) Using the Everted Intestine Assay. International Journal of Molecular Sciences 2021; 22(3): 1049 doi: 10.3390/ijms22031049
|
162 |
Zheng Lu, Jennifer Sheng, Wenhui Zhang. Protein Therapeutics. Methods and Principles in Medicinal Chemistry 2017; : 311 doi: 10.1002/9783527699124.ch10
|
163 |
Christopher Banfield, Dan Rudin, Indranil Bhattacharya, Kosalaram Goteti, Gang Li, Mina Hassan‐Zahraee, Lisa S. Brown, Kenneth E. Hung, Sylvester Pawlak, Christopher Lepsy. First‐in‐human, randomized dose‐escalation study of the safety, tolerability, pharmacokinetics, pharmacodynamics and immunogenicity of PF‐06480605 in healthy subjects. British Journal of Clinical Pharmacology 2020; 86(4): 812 doi: 10.1111/bcp.14187
|
164 |
Hyunseok Oh, Younghun Jung, Seokoh Moon, Jaehyeon Hwang, Choongjin Ban, Jinhyo Chung, Woo-Jae Chung, Dae-Hyuk Kweon. Development of End-Spliced Dimeric Nanodiscs for the Improved Virucidal Activity of a Nanoperforator. ACS Applied Materials & Interfaces 2021; 13(31): 36757 doi: 10.1021/acsami.1c06364
|
165 |
Zhengqi Zhang, Yuetian Yan, Shunhai Wang, Ning Li. Development of a Chromatography-Free Method for High-Throughput MS-Based Bioanalysis of Therapeutic Monoclonal Antibodies. Bioanalysis 2021; 13(9): 725 doi: 10.4155/bio-2021-0021
|
166 |
P. Lakshmikanth Reddy, Sangeetha Shanmugasundaram. Optimizing Process Parameters for Controlled Drug Delivery: A Quality by Design (QbD) Approach in Naltrexone Microspheres. AAPS PharmSciTech 2024; 25(5) doi: 10.1208/s12249-024-02830-w
|
167 |
Zenjiro Sampei, Tomoyuki Igawa, Tetsuhiro Soeda, Yukiko Okuyama-Nishida, Chifumi Moriyama, Tetsuya Wakabayashi, Eriko Tanaka, Atsushi Muto, Tetsuo Kojima, Takehisa Kitazawa, Kazutaka Yoshihashi, Aya Harada, Miho Funaki, Kenta Haraya, Tatsuhiko Tachibana, Sachiyo Suzuki, Keiko Esaki, Yoshiaki Nabuchi, Kunihiro Hattori, Peter J. Lenting. Identification and Multidimensional Optimization of an Asymmetric Bispecific IgG Antibody Mimicking the Function of Factor VIII Cofactor Activity. PLoS ONE 2013; 8(2): e57479 doi: 10.1371/journal.pone.0057479
|
168 |
Mark Milton. Monoclonal Antibodies: Development, Delivery and Applications. 2015; : 58 doi: 10.4155/fseb2013.14.229
|
169 |
Byung-yo Lee, Kwang-il Kwon, Min-Soo Kim, In-hwan Baek. Michaelis–Menten elimination kinetics of etanercept, rheumatoid arthritis biologics, after intravenous and subcutaneous administration in rats. European Journal of Drug Metabolism and Pharmacokinetics 2016; 41(4): 433 doi: 10.1007/s13318-015-0270-9
|
170 |
Melody Sauerborn, William van Dongen. Practical Considerations for the Pharmacokinetic and Immunogenic Assessment of Antibody–Drug Conjugates. BioDrugs 2014; 28(4): 383 doi: 10.1007/s40259-014-0096-z
|
171 |
Amrita V. Kamath. Translational pharmacokinetics and pharmacodynamics of monoclonal antibodies. Drug Discovery Today: Technologies 2016; : 75 doi: 10.1016/j.ddtec.2016.09.004
|
172 |
Kip P. Conner, Siva Charan Devanaboyina, Veena A. Thomas, Dan A. Rock. The biodistribution of therapeutic proteins: Mechanism, implications for pharmacokinetics, and methods of evaluation. Pharmacology & Therapeutics 2020; 212: 107574 doi: 10.1016/j.pharmthera.2020.107574
|
173 |
Susanne Beyer, Li Xie, Mike Schmidt, Natasja de Bruin, Mukul Ashtikar, Sabrina Rüschenbaum, Christian M. Lange, Vitali Vogel, Werner Mäntele, Michael J. Parnham, Matthias G. Wacker. Optimizing novel implant formulations for the prolonged release of biopharmaceuticals using in vitro and in vivo imaging techniques. Journal of Controlled Release 2016; 235: 352 doi: 10.1016/j.jconrel.2016.06.013
|
174 |
Ian N. Foltz, Margaret Karow, Scott M. Wasserman. Evolution and Emergence of Therapeutic Monoclonal Antibodies. Circulation 2013; 127(22): 2222 doi: 10.1161/CIRCULATIONAHA.113.002033
|
175 |
Ola M Saad, Ben-Quan Shen, Keyang Xu, S Cyrus Khojasteh, Sandhya Girish, Surinder Kaur. Bioanalytical Approaches for Characterizing Catabolism of Antibody–Drug Conjugates. Bioanalysis 2015; 7(13): 1583 doi: 10.4155/bio.15.87
|
176 |
Igor Mikaelian, Mark Cameron, Deidre A. Dalmas, Bradley E. Enerson, Raymond J. Gonzalez, Silvia Guionaud, Peter K. Hoffmann, Nicholas M. P. King, Michael P. Lawton, Marshall S. Scicchitano, Holly W. Smith, Roberta A. Thomas, James L. Weaver, Tanja S. Zabka. Nonclinical Safety Biomarkers of Drug-induced Vascular Injury. Toxicologic Pathology 2014; 42(4): 635 doi: 10.1177/0192623314525686
|
177 |
Simone Schadt, Christophe Husser, Roland F. Staack, Aynur Ekiciler, Na Hong Qiu, Stephen Fowler, Christoph Funk, Nicole A. Kratochwil. The In Vitro Biotransformation of the Fusion Protein Tetranectin-Apolipoprotein A1. Scientific Reports 2019; 9(1) doi: 10.1038/s41598-019-40542-5
|
178 |
Jinze Li, Mayur S. Mitra, Gautham K. Rao. Immuno-Oncology. Methods in Pharmacology and Toxicology 2020; : 199 doi: 10.1007/978-1-0716-0171-6_12
|
179 |
Azam Bolhassani. Improvements in chemical carriers of proteins and peptides. Cell Biology International 2019; 43(4): 437 doi: 10.1002/cbin.11108
|
180 |
Nkiruka Ibeanu, Raphael Egbu, Lesley Onyekuru, Hoda Javaheri, Peng Tee Khaw, Gareth R. Williams, Steve Brocchini, Sahar Awwad. Injectables and Depots to Prolong Drug Action of Proteins and Peptides. Pharmaceutics 2020; 12(10): 999 doi: 10.3390/pharmaceutics12100999
|
181 |
Michael Schmohl, Nicole Schneiderhan-Marra, Nadja Baur, Kathrin Hefner, Michael Blum, Gerburg M. Stein, Thomas O. Joos, Manfred Schmolz. Characterization of immunologically active drugs in a novel organotypic co-culture model of the human gut and whole blood. International Immunopharmacology 2012; 14(4): 722 doi: 10.1016/j.intimp.2012.10.010
|
182 |
Eszter Lázár-Molnár, Julio C Delgado. Implications of Monoclonal Antibody Therapeutics Use for Clinical Laboratory Testing. Clinical Chemistry 2019; 65(3): 393 doi: 10.1373/clinchem.2016.266973
|
183 |
Björn Boll, Juliana Bessa, Emilien Folzer, Anacelia Ríos Quiroz, Roland Schmidt, Patrick Bulau, Christof Finkler, Hanns-Christian Mahler, Jörg Huwyler, Antonio Iglesias, Atanas V. Koulov. Extensive Chemical Modifications in the Primary Protein Structure of IgG1 Subvisible Particles Are Necessary for Breaking Immune Tolerance. Molecular Pharmaceutics 2017; 14(4): 1292 doi: 10.1021/acs.molpharmaceut.6b00816
|
184 |
Tim Jones, Anette Karle, Matthew Baker. Developability of Biotherapeutics. 2015; : 85 doi: 10.1201/b19023-6
|
185 |
Rajan Swami, Aliasgar Shahiwala. Impact of physiochemical properties on pharmacokinetics of protein therapeutics. European Journal of Drug Metabolism and Pharmacokinetics 2013; 38(4): 231 doi: 10.1007/s13318-013-0126-0
|
186 |
Sumel Ashique, Ashish Garg, Ekta Sirohi, Shubneesh Kumar, S. Mohanalakshmi, Neeraj Mishra. Peptide and Protein Drug Delivery Using Polysaccharides. 2024; : 261 doi: 10.1016/B978-0-443-18925-8.00004-0
|
187 |
Mengbi Yang, Yuanfeng Lyu, Zhong Zuo. Oral Bioavailability and Drug Delivery. 2023; : 501 doi: 10.1002/9781119660699.ch26
|
188 |
Jasbir Singh, Fawzy Elbarbry, Ke Lan, Tomasz Grabowski. Animal Pharmacokinetic/Pharmacodynamic Studies (APPS) Reporting Guidelines. European Journal of Drug Metabolism and Pharmacokinetics 2018; 43(5): 483 doi: 10.1007/s13318-018-0498-2
|
189 |
Pramodkumar P. Gupta, Mala M. Parab, Santosh S. Chhajed, Virupaksha A. Bastikar. Protein-based Therapeutics. 2023; : 275 doi: 10.1007/978-981-19-8249-1_10
|
190 |
Jonathan Moreno, Khalid Zoghebi, David Salehi, Lois Kim, Sorour Khayyatnejad Shoushtari, Rakesh K. Tiwari, Keykavous Parang. Amphiphilic Cell-Penetrating Peptides Containing Arginine and Hydrophobic Residues as Protein Delivery Agents. Pharmaceuticals 2023; 16(3): 469 doi: 10.3390/ph16030469
|
191 |
Piotr Pierog, Murli Krishna, Aaron Yamniuk, Anil Chauhan, Binodh DeSilva. Detection of drug specific circulating immune complexes from in vivo cynomolgus monkey serum samples. Journal of Immunological Methods 2015; 416: 124 doi: 10.1016/j.jim.2014.11.007
|
192 |
Anita O’Connor, Mark Rogge. Nonclinical Development of A Biosimilar: The Current Landscape. Bioanalysis 2013; 5(5): 537 doi: 10.4155/bio.13.7
|
193 |
Sahar Awwad, Alastair Lockwood, Steve Brocchini, Peng T. Khaw. The PK-Eye: A Novel In Vitro Ocular Flow Model for Use in Preclinical Drug Development. Journal of Pharmaceutical Sciences 2015; 104(10): 3330 doi: 10.1002/jps.24480
|
194 |
Vishakha Tambe, Havish Shukla, Kuldeep Rajpoot, Murali Monohar Pandey, Rakesh Kumar Tekade. Biopharmaceutics and Pharmacokinetics Considerations. 2021; : 539 doi: 10.1016/B978-0-12-814425-1.00012-7
|
195 |
Blaise Pasquiers, Salih Benamara, Mathieu Felices, Laurent Nguyen, Xavier Declèves. Review of the Existing Translational Pharmacokinetics Modeling Approaches Specific to Monoclonal Antibodies (mAbs) to Support the First-In-Human (FIH) Dose Selection. International Journal of Molecular Sciences 2022; 23(21): 12754 doi: 10.3390/ijms232112754
|
196 |
Patrick McMullen, Qi Qiao, Sijin Luozhong, Lirong Cai, Liang Fang, Qing Shao, Shaoyi Jiang. Motif-based zwitterionic peptides impact their structure and immunogenicity. Chemical Science 2022; 13(36): 10961 doi: 10.1039/D2SC03519G
|
197 |
Ray Bakhtiar. Antibody drug conjugates. Biotechnology Letters 2016; 38(10): 1655 doi: 10.1007/s10529-016-2160-x
|
198 |
Anshu Kuriakose, Narendra Chirmule, Pradip Nair. Immunogenicity of Biotherapeutics: Causes and Association with Posttranslational Modifications. Journal of Immunology Research 2016; 2016: 1 doi: 10.1155/2016/1298473
|
199 |
Cristina Dainese, Federica Valeri, Benedetto Bruno, Alessandra Borchiellini. Anti-ADAMTS13 Autoantibodies: From Pathophysiology to Prognostic Impact—A Review for Clinicians. Journal of Clinical Medicine 2023; 12(17): 5630 doi: 10.3390/jcm12175630
|