Copyright
©The Author(s) 2016.
World J Gastrointest Surg. Mar 27, 2016; 8(3): 266-273
Published online Mar 27, 2016. doi: 10.4240/wjgs.v8.i3.266
Published online Mar 27, 2016. doi: 10.4240/wjgs.v8.i3.266
Table 1 Studies of fibrin sealant at pilonidal sinus: Demographics of the patients
Ref. | Year | Country | Study period | No. | Male | Age | BMI or weight |
Greenberg et al[4] | 2004 | Israel | Jun 2001 to Dec 2001 | 30 | 22 | 23.5 ± 2.8 (17-44) | NA |
Lund et al[5] | 2005 | United Kingdom | NA | 6 | 6 | 28.5 ± 5.5 (22-44) | NA |
Seleem et al[6] | 2005 | Saudi Arabia | Sep 2001 to Feb 2004 | 25 | 23 | 26.4 ± 8.5 (17-50) | NA |
Patti et al[7] | 2006 | Italy | NA | 8 | 8 | 21.8 ± 6.5 | NA |
Altinli et al[8] | 2007 | Turkey | Jan 2003 to Jan 2004 | 16 | 16 | 24.5 ± 6.0 | 25.7 + 4.1 kg/m2 |
Sözen et al[9] | 2011 | Turkey | Jan 2008 to Mar 2008 | 25 | 25 | 22.5 ± 4.0 (20-36) | 26 kg/m2 |
Elsey et al[10] | 2013 | United Kingdom | Mar 2007 to Sep 2011 | 57 | 42 | 26.0 ± 13.3 (17–70) | NA |
Isik et al[11] | 2014 | Turkey | Dec 2007 to Dec 2011 | 40 | 32 | 24.0 ± 8.5 (16-50) | NA |
Smith et al[12] | 2014 | United Kingdom | Aug 2006 to Dec 2013 | 10 | NA | 14.5 ± 1.0 (12–16) | 73 kg |
Total | Jun 2001 to Dec 2013 | 217 | 84% | 24.2 ± 7.8 (12-70) |
Table 2 Studies of fibrin sealant at pilonidal sinus: Features of the pilonidal sinuses
Ref. | No. | Inclusion and exclusion criteria | Recurrent |
Greenberg et al[4] | 30 | No exclusion criteria | 8 |
Lund et al[5] | 6 | 3-4 openings and no large cavity | 3 |
Seleem et al[6] | 25 | 1-3 openings, no prior surgery, no infection | 0 |
Patti et al[7] | 8 | 3 < openings, no prior surgery, no infection, no large cavity or distant orifice | 0 |
Altinli et al[8] | 16 | No prior surgery | 0 |
Sözen et al[9] | 25 | No prior surgery, no infection, no lateral extension < 3 cm | 0 |
Elsey et al[10] | 57 | No infection, no very scarred cases due to repeated episodes or surgeries | 2 |
Isik et al[11] | 40 | Only 1 opening, no prior surgical or medical treatment, no infection | 0 |
Smith et al[12] | 10 | No exclusion criteria | 0 |
Total | 217 | 13 (6%) |
Table 3 Studies of fibrin sealant at pilonidal sinus: Procedures
Ref. | No. | Surgical procedure | Aim of using fibrin sealant |
Greenberg et al[4] | 30 | Excision and primary closure | Obliterate the dead space under the wound |
Lund et al[5] | 6 | No sinus excision, only cleaning the tracts | Fill the tracts with sealent |
Seleem et al[6] | 25 | Excision and lay open | Overlap the open wound with sealent |
Patti et al[7] | 8 | Excision and lay open | Overlap the open wound with sealent |
Altinli et al[8] | 16 | Excision and closure with Limberg flap | Obliterate the dead space under the wound |
Sözen et al[9] | 25 | Excision and closure with Karydakis flap | Obliterate the dead space under the wound |
Elsey et al[10] | 57 | No sinus excision, only cleaning the tracts | Fill the tracts with sealent |
Isik et al[11] | 40 | No sinus excision, only cleaning the tracts | Fill the tracts with sealent |
Smith et al[12] | 10 | No sinus excision, only cleaning the tracts | Fill the tracts with sealent |
Table 4 Surgical details
Ref. | No. | Anesthesia | Amount of glue | Drain |
Greenberg et al[4] | 30 | General or spinal | 2-4 mL | None |
Lund et al[5] | 6 | General | 1-2 mL | None |
Seleem et al[6] | 25 | Local (n = 23), general (n = 2) | NA | None |
Patti et al[7] | 8 | Local | 1.9 ± 0.6 mL | None |
Altinli et al[8] | 16 | Spinal | 6 mL | Yes |
Sözen et al[9] | 25 | NA | 6 mL | None |
Elsey et al[10] | 57 | General | NA | None |
Isik et al[11] | 40 | Local | 2-4 mL | None |
Smith et al[12] | 10 | General | NA | None |
Total | 217 | Local 39% | 3.8 (1-6) | 7.3% |
Table 5 Obliterating the dead space under the closed wound with sealent
Table 6 Studies on covering the open wound with fibrin sealant after excision
Table 7 Studies on filling the tracts with fibrin sealant
- Citation: Kayaalp C, Ertugrul I, Tolan K, Sumer F. Fibrin sealant use in pilonidal sinus: Systematic review. World J Gastrointest Surg 2016; 8(3): 266-273
- URL: https://www.wjgnet.com/1948-9366/full/v8/i3/266.htm
- DOI: https://dx.doi.org/10.4240/wjgs.v8.i3.266