Short-term efficacy of laparoscopy-assisted vs open radical gastrectomy in gastric cancer

Table 1 Patients characteristics n (%)

	LARG	ORG	P value
Sex (male/female)	109/91	112/88	0.84
Age (yr)	58.3 ± 6.5	58.6 ± 6.3
Pathological type
Well-differentiated adenocarcinoma	49 (24.5)	38 (19.0)	0.321
Moderately-differentiated adenocarcinoma	23 (11.5)	31 (15.5)
Poorly-differentiated adenocarcinoma	115 (57.5)	122 (61.0)
Signet ring cell carcinoma	13 (6.5)	9 (4.5)
Classification (T)
T1	18 (9.0)	15 (7.5)	0.862
T2	89 (44.5)	91 (45.5)
T3	93 (46.5)	94 (47.0)
Lymph node metastasis
N0	13 (6.5)	11 (5.5)	0.903
N1	88 (44.0)	91 (45.5)
N2	99 (49.5)	98 (49.0)
Clinical stage
I + II	91 (45.5)	89 (44.5)	0.92
III + IV	109 (54.5%)	111 (55.5)

¹Well-differentiated adenocarcinoma group of LARG and ORG;

²T1 group of LARG and ORG;

³I + II group of LARG and ORG. LARG: Laparoscopic radical gastrectomy; ORG: Open radical gastrectomy.

Table 2 Comparison of surgical outcomes between laparoscopic radical gastrectomy and open radical gastrectomy groups

Outcomes	LARG	ORG	P value
Operation time (min)	192.3 ± 20.9	180.0 ± 26.9	< 0.0001
No. of lymph nodes removed	28.5 ± 4.5	28.3 ± 3.4	0.62
Intraoperative blood loss (mL)	103.1 ± 19.5	163.0 ± 32.9	< 0.0001
Bedbound time (d)	1.0 ± 0.3	3.3 ± 0.4	< 0.0001
Time to bowel opening (d)	3.3 ± 0.7	4.5 ± 0.7	< 0.0001
Length of incision (cm)	5.2 ± 0.7	17.8 ± 1.0	< 0.0001
Time to normal diet (d)	3.0 ± 0.4	3.8 ± 0.5	< 0.0001
Total hospital stay (d)	6.8 ± 1.2	9.5 ± 1.6	< 0.0001

LARG: Laparoscopic radical gastrectomy; ORG: Open radical gastrectomy.

Table 3 Comparison of postoperative complications between the two groups n (%)

Postoperative complications	LARG	ORG	P value
Decreased gastrointestinal motility	3 (1.5)	7 (3.5)	0.2
Anastomotic leakage/stump fistula	7 (3.5)	15 (7.5)	0.08
Poor incision healing	5 (2.5)	16 (8.0)	0.01
Pulmonary infection	4 (2.0)	19 (9.5)	0.001
Acute liver/kidney failure	1 (0.5)	4 (2.0)	0.18
Total	131 (6.5)	271 (13.5)	0.02

¹Some patients had two or more concomitant complications. LARG: Laparoscopic radical gastrectomy; ORG: Open radical gastrectomy.