Copyright
©The Author(s) 2025.
World J Gastrointest Surg. Aug 27, 2025; 17(8): 107706
Published online Aug 27, 2025. doi: 10.4240/wjgs.v17.i8.107706
Published online Aug 27, 2025. doi: 10.4240/wjgs.v17.i8.107706
Table 1 Characteristics of included studies
| Ref. | Country | Study period | Design | No. patients | Age1 | Sex, M/F | Approach | Reconstruction techniques |
| Shibasaki et al[26], 2017 | Japan | 2014-2015 | Single-center retrospective study | 12 | 67 | 9/3 | RPG | Kamikawa |
| Kumamoto et al[27], 2021 | Japan | 2011-2016 | Single-center retrospective study | 34 | 64.3 | 30/4 | OPG | Kamikawa/JI |
| Wu et al[30], 2024 | China | 2020-2022 | Single-center retrospective study | 42 | 68.3 | 34/8 | LPG | Kamikawa/DTR |
| Kuroda et al[19], 2016 | Japan | 2011-2015 | Single-center retrospective study | 33 | 73 | 26/7 | LPG | Kamikawa |
| Nishimura et al[28], 2023 | Japan | 2011-2018 | Single-center retrospective study | 43 | 67 | 31/4 | LPG | Kamikawa/DTR |
| Saze et al[29], 2021 | Japan | 2005-2020 | Single-center retrospective study | 60 | 70.1 | 45/15 | LPG, RPG | Kamikawa/DTR/JIP |
| Kuroda et al[18], 2019 | Japan | 1996-2015 | Multi-center retrospective study | 546 | 68.2 | 407/139 | OPG, LPG | Kamikawa |
| Hosoda et al[23], 2019 | Japan | 2015-2018 | Single-center retrospective study | 91 | 69.5 | 36/38 | LPG | Kamikawa/OrVil |
| Shoji et al[25], 2019 | Japan | 2013-2017 | Single-center retrospective study | 147 | 67 | 113/34 | LPG | Kamikawa |
| Wu et al[24], 2024 | China | 2016-2022 | Single-center retrospective study | 268 | 69 | 186/82 | LPG | Kamikawa/LTG-Roux-en-Y |
| Hayami et al[31], 2017 | Japan | 2013-2014 | Single-center retrospective study | 90 | 72 | 65/25 | LPG | Kamikawa/LTG-Roux-en-Y |
| Long et al[32], 2022 | Japan | 2018-2021 | Single-center retrospective study | 14 | 54 | 10/4 | LPG | Kamikawa |
| Yu et al[15], 2022 | Korea | 2014-2018 | Single-center retrospective study | 69 | 63.2 | 50/19 | LPG | Kamikawa/DTR |
| Kuroda et al[33], 2024 | Japan | NA | Multi-center prospective study | 39 | 72.3 | 28/11 | LPG | Kamikawa |
| Kano et al[39], 2020 | Japan | 2006-2015 | Single-center retrospective study | 161 | 71 | 110/48 | LPG | Kamikawa/LTG-Roux-en-Y |
| Matsuo et al[34], 2023 | Japan | 2013-2021 | Single-center retrospective study | 80 | 69 | 63/17 | LPG, RPG | Kamikawa |
| Ri et al[35], 2021 | Japan | 2013-2017 | Single-center retrospective study | 158 | 68 | 123/35 | LPG | Kamikawa |
| Hu et al[36], 2024 | Japan | 2009-2023 | Single-center retrospective study | 313 | 68 | 241/72 | LPG, RPG | Kamikawa |
| Tsumura et al[37], 2020 | Japan | 2011-2014 | Single-center retrospective study | 36 | 71.2 | 27/9 | LPG | Kamikawa/LTG-Roux-en-Y |
| Shibamoto et al[38], 2023 | Japan | 2017-2021 | Single-center retrospective study | 55 | 65.3 | 35/20 | LPG | Kamikawa/LTG-Roux-en-Y |
Table 2 Surgical characteristics
| Ref. | Extent of lymph node dissection | Operative time, minutes1 | Blood loss, mL1 | Anastomotic time, minutes1 | Dissected lymph nodes1 | Pathological stage, n | |||
| D1 | D1+ | I | II | III | |||||
| Shibasaki et al[26], 2017 | 1 | 11 | 295.08 (83.999) | 54.5 (42.9) | 114.8 (36.4) | NA | NA | NA | NA |
| Kumamoto et al[27], 2021 | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Wu et al[30], 2024 | NA | NA | 199.2 (71.3) | 21.0 (3.8) | 94.7 (30.1) | NA | NA | NA | NA |
| Kuroda et al[19], 2016 | NA | NA | 304.2 (170.5) | NA | 109.4 (81.4) | NA | NA | NA | NA |
| Nishimura et al[28], 2023 | NA | NA | 274.3 (40.2) | 8.8 (10.7) | NA | NA | 32 | 11 | 0 |
| Saze et al[29], 2021 | 11 | 49 | NA | NA | NA | NA | 56 | 4 | 0 |
| Kuroda et al[18], 2019 | NA | NA | 240.2 (47.9) | 50.6 (6.0) | NA | NA | NA | NA | |
| Hosoda et al[23], 2019 | 41 | 50 | 373.4 (96.2) | NA | NA | NA | 79 | 6 | 2 |
| Shoji et al[25], 2019 | NA | NA | 421.9 (75.4186) | 93.4 (125.4) | NA | 33.0 (12.5) | 124 | 13 | 2 |
| Wu et al[24], 2024 | NA | NA | 195.9 (25.0) | 21.6 (8.6) | 92.6 (29.0) | NA | NA | NA | NA |
| Hayami et al[31], 2017 | 0 | 90 | 386.5 (78.9) | 125.0 (153.3) | NA | 31.9 (11.4) | 83 | 4 | 3 |
| Long et al[32], 2022 | NA | NA | 261.5 (70.0) | 95.6 (72.5) | 85.6 (26.4) | NA | NA | NA | NA |
| Yu et al[15], 2022 | NA | NA | 235.3 (115.4) | NA | NA | NA | 67 | 2 | 0 |
| Kuroda et al[33], 2024 | 0 | 39 | 329.5 (64.9) | 71.9 (73.4) | 96.5 (70.8) | NA | 37 | 1 | 1 |
| Kano et al[39], 2020 | NA | NA | 395.9 (81.6) | 72.6 (69.4) | NA | NA | 152 | 9 | 0 |
| Matsuo et al[34], 2023 | NA | NA | 366.7 (58.3) | 60.2 (89.1) | NA | 27.9 (12.6) | NA | NA | NA |
| Ri et al[35], 2021 | NA | NA | 420.7 (76.3) | 78.4 (71.8) | NA | 34.4 (9.7) | 146 | 12 | 0 |
| Hu et al[36], 2024 | NA | NA | 393.5 (93.0) | 62.8 (118.4) | NA | 36.3 (10.3) | NA | NA | NA |
| Tsumura et al[37], 2020 | NA | NA | 297.7 (64.9) | 203.1 (52.8) | NA | NA | 32 | 4 | 0 |
| Shibamoto et al[38], 2023 | NA | NA | NA | NA | NA | NA | NA | NA | NA |
Table 3 Short- and long-term outcomes of Kamikawa
| Ref. | Early complications, n (%) | Hospital stays (days) | Reflux esophagitis, n (%) | Anastomotic-associated complications, n (%) | BWL at one year postoperatively1 | PPI intake, n (%) | |||
| Overall | CD ≥ IIIa | Anastomotic stenosis | Anastomotic leakage | Anastomotic hemorrhage | |||||
| Shibasaki et al[26], 2017 | 1 (8.3) | NA | 12.2 (5.8) | 3 (25.0) | 3 (25.0) | NA | NA | NA | NA |
| Kumamoto et al[27], 2021 | 2 (14.0) | NA | 14.2 (6.6) | NA | NA | 1 (7.0) | NA | -8.1% | NA |
| Wu et al[30], 2024 | 1 (4.5) | NA | 8.4 (2.4) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | -12.6% | NA |
| Kuroda et al[19], 2016 | NA | NA | NA | 3 (9.0) | 3 (9.0) | NA | 0 (0) | NA | NA |
| Nishimura et al[28], 2023 | 6 (17.0) | NA | NA | NA | NA | NA | NA | NA | 18 (50.0) |
| Saze et al[29], 2021 | 5 (13.9) | NA | 10.5 (3.3) | 3 (8.3) | 3 (8.3) | NA | NA | NA | 6 (16.7) |
| Kuroda et al[18], 2019 | 11 (2.0) | NA | 16.1 (5.2) | 30 (5.5) | 30 (5.5) | 8 (1.5) | 3 (0.6) | -11.30% | 135 (24.7) |
| Hosoda et al[23], 2019 | 3 (7.5) | NA | 10.8 (5.1) | 7 (17.5) | 7 (17.5) | 1 (2.5) | 0 (0) | NA | NA |
| Shoji et al[25], 2019 | 18 (12.2) | 10 (6.8) | 11.4 (7.2) | 12 (8.3) | 12 (8.3) | 5 (3.4) | 1 (0.7) | NA | NA |
| Wu et al[24], 2024 | 1 (3.8) | NA | 9 (1.6) | NA | NA | 0 (0) | 0 (0) | NA | NA |
| Hayami et al[31], 2017 | 3 (7.0) | 3 (7.0) | 11.7 (5.5) | 2 (4.7) | 2 (4.7) | 0 (0) | 0 (0) | -12.0% | NA |
| Long et al[32], 2022 | 1 (7.1) | NA | 9 (1.6) | 1 (7.1) | 1 (7.1) | 0 (0) | 0 (0) | NA | NA |
| Yu et al[15], 2022 | 4 (22.2) | 1 (5.6) | NA | 2 (4.7) | 2 (4.7) | 0 (0) | NA | -8.3% | 0 |
| Kuroda et al[33], 2024 | 6 (15.4) | NA | NA | 2 (5.3) | 2 (5.3) | 2 (5.1) | NA | -11.1% | NA |
| Kano et al[39], 2020 | 5 (10.0) | 3 (6.0) | NA | 4 (8.0) | 4 (8.0) | 0 (0) | 0 (0) | NA | NA |
| Matsuo et al[34], 2023 | 4 (5.0) | 4 (5.0) | 14.4 (8.9) | 21 (26.3) | 21 (26.3) | 1 (1.3) | NA | -12.6% | 27 (33.7) |
| Ri et al[35], 2021 | 33 (20.9) | 14 (8.9) | NA | NA | NA | 5 (3.2) | NA | NA | NA |
| Hu et al[36], 2024 | 19 (8.2) | 19 (8.2) | 8.7 (5.6) | 27 (12.1) | 27 (12.1) | 7 (3.0) | NA | -12.4% | 40 (18.1) |
| Tsumura et al[37], 2020 | 2 (11.0) | NA | 12.4 (2.4) | 1 (5.0) | 1 (5.0) | 0 (0) | NA | NA | NA |
| Shibamoto et al[38], 2023 | 5 (23.8) | NA | NA | NA | NA | NA | NA | NA | NA |
- Citation: Liu CC, Yang J, Yin G, Tian Z, Qin C. Kamikawa anastomosis in proximal gastrectomy for gastric cancer: A systematic review and meta-analysis. World J Gastrointest Surg 2025; 17(8): 107706
- URL: https://www.wjgnet.com/1948-9366/full/v17/i8/107706.htm
- DOI: https://dx.doi.org/10.4240/wjgs.v17.i8.107706