Efficacy of laparoscopic radical resection of colorectal cancer in older patients and its effects on inflammatory factors

Table 1 General information of the two groups

Indicators	Control group (n = 50)	Research group (n = 54)	χ2/t	P value
Gender (male/female)	27/23	30/24	0.025	0.874
Age (years)	69.16 ± 5.48	68.54 ± 5.19	0.636	0.526
Disease course (years)	2.52 ± 0.61	2.46 ± 0.97	0.406	0.686
Tumor type (rectal/colon cancer)	28/22	32/22	0.113	0.737
TNM staging (I/II/III)	9/26/15	8/23/23	1.775	0.412

TNM: Tumor-node-metastasis.

Table 2 Therapeutic efficacy in the two groups, n (%)

Indicators	Control group (n = 50)	Research group (n = 54)	χ2	P value
Markedly effective	10 (20.00)	18 (33.33)
Effective	13 (26.00)	15 (27.78)
Relatively effective	12 (24.00)	14 (25.93)
Ineffective	15 (30.00)	7 (12.96)
Overall effective	35 (70.00)	47 (87.04)	4.518	0.034

Table 3 Postoperative complications in the two groups, n (%)

Indicators	Control group (n = 50)	Research group (n = 54)	χ2	P value
Ileus	4 (8.00)	2 (3.70)
Incision infection	6 (12.00)	1 (1.85)
Anastomotic fistula	4 (8.00)	0 (0.00)
Pulmonary infection	2 (4.00)	2 (3.70)
Total	16 (32.00)	5 (9.26)	8.331	0.004

Table 4 Surgery-related parameters of the two groups

Indicators	Control group (n = 50)	Research group (n = 54)	t	P value
Operation duration (minutes)	124.70 ± 26.71	175.93 ± 44.01	7.107	< 0.001
Intraoperative bleeding volume (mL)	85.34 ± 10.01	56.80 ± 7.53	16.508	< 0.001

Table 5 Postoperative recovery-related indicators in the two groups

Indicators	Control group (n = 50)	Research group (n = 54)	t	P value
Time to first postoperative passage of flatus (days)	3.74 ± 1.34	2.22 ± 0.77	7.158	< 0.001
Time to first postoperative defecation (days)	5.22 ± 1.67	3.87 ± 1.35	4.549	< 0.001
Length of hospital stay (days)	12.76 ± 3.46	9.81 ± 2.49	5.018	< 0.001

Table 6 Inflammatory factors in the two groups

Indicators	Control group (n = 50)	Research group (n = 54)	t	P value
TNF-α (ng/L)
Before surgery	494.90 ± 90.86	501.65 ± 87.21	0.387	0.700
After surgery	446.36 ± 55.33	355.94 ± 69.70	7.289	< 0.001
hs-CRP (mg/L)
Before surgery	7.80 ± 2.27	7.27 ± 2.28	1.187	0.238
After surgery	6.27 ± 1.99	5.22 ± 1.41	3.123	0.002
IL-6 (μg/L)
Before surgery	351.98 ± 44.19	359.65 ± 59.62	0.741	0.461
After surgery	309.06 ± 44.88	220.09 ± 38.14	10.920	< 0.001

TNF-α: Tumor necrosis factor-α; hs-CRP: High-sensitivity C-reactive protein; IL-6: Interleukin-6.