Construction of a nomogram prediction model for early postoperative stoma complications of colorectal cancer

Table 1 Comparison of baseline data between the training set and the validation set after ostomy for colorectal cancer

Variable	Train (n = 326)	Vadi (n = 136)	χ2	P value
Sex (male/female, n)	194/132	132/95	4.383	0.036
Age (< 65/≥ 65, n)	134/192	58/78	0.094	0.759
BMI (< 18.5 kg/m2/18.5-23.9 kg/m2/> 23.9 kg/m2, n)	24/179/123	17/75/44	3.623	0.163
Diabetes (yes/no, n)	40/286	18/118	0.081	0.775
Neoadjuvant therapy (yes/no, n)	17/309	11/125	1.392	0.258
Differentiation degree (low differentiation/medium differentiation/high differentiation, n)	102/221/3	47/88/1	0.493	0.782
TNM staging (I/II/III, n)	75/109/142	76/59/61	8.804	0.012
Tumor location (right colon/left colon/sigmoid colon/rectum, n)	17/6/20/283	9/1/10/116	1.354	0.716
Stoma type (Ileostomy/colonostomy, n)	227/99	90/46	0.532	0.466
NRS2002 score (< 3/≥ 3, n)	224/82	98/38	0.388	0.533
PNI (≤ 45.9/> 45.9, n)	76/250	58/78	0.094	0.759
WBC (≤ 7.135/> 7.135, n)	260/66	108/28	0.007	0.938
NLR (≤ 2.4813/> 2.4813, n)	171/155	71/65	0.002	0.961
PLR (≤ 125.425/> 125.425, n)	120/206	47/89	0.211	0.646
Complications (yes/no, n)	68/258	32/104	0.404	0.525

BMI: Body mass index; TNM: Tumor-node-metastasis; NRS: Nutritional risk screening; PNI: Prognostic nutritional index; WBC: White blood cell count; NLR: Neutrophil-lymphocyte ratio; PLR: Platelet count and lymphocyte count ratio.

Table 2 Univariate analysis results for early complications after ostomyfor colorectal cancer

Variable	Train early ostomy complications
	Yes (n = 68)	No (n = 258)	χ2	P value
Sex			0.963	0.326
Male	44	150
Female	24	108
Diabetes			10.119	0.001
Yes	16	24
No	52	234
Age			1.198	0.274
< 65	24	110
≥ 65	41	148
BMI			1.911	0.385
< 18.5 kg/m2	7	17
18.5-23.9 kg/m2	33	146
> 23.9 kg/m2	28	95
Neoadjuvant therapy			20.888	< 0.001
Yes	11	6
No	57	252
Differentiation degree			2.576	0.276
Highly differentiated	0	3
Middle differentiation	42	179
Low differentiation	26	76
TNM staging			0.871	0.647
I	18	57
II	20	89
III	30	112
Tumor location			4.395	0.222
Right colon	5	12
Left colon	3	3
Sigmoid colon	5	15
Rectum colon	55	228
Stoma type			13.402	< 0.001
Ileostomy	35	192
Colonostomy	33	66
NRS 2002 score			7.611	0.005
< 3	42	202
≥ 3	26	56
PNI			12.915	< 0.001
≤ 49.5	27	49
> 49.5	41	209
WBC			0.574	0.449
≤ 7.5	52	208
> 7.5	16	50
NLR			13.920	< 0.001
≤ 2.4813	22	149
> 2.4813	46	109
PLR			6.515	0.011
≤ 125.425	16	104
> 125.425	52	154

BMI: Body mass index; TNM: Tumor-node-metastasis; NRS: Nutritional risk screening; PNI: Prognostic nutritional index; WBC: White blood cell count; NLR: Neutrophil-lymphocyte ratio; PLR: Platelet count and lymphocyte count ratio.

Table 3 Results of the multivariate regression analysis of early complications after ostomy for colorectal cancer

Variable	β value	SE value	Wald χ2 value	RR (95%CI)	P value
Diabetes	1.128	0.397	8.083	1.419-6.719	0.004
Neoadjuvant therapy	1.920	0.584	10.808	2.171-21.433	0.001
Stoma type	0.750	0.311	5.816	1.151-3.898	0.016
NRS 2002 score	0.710	0.322	4.861	1.082-3.822	0.027
NLR	0.546	0.330	2.739	0.904-3.294	0.098
PLR	0.479	0.357	1.800	0.802-3.250	0.180
PNI	-0.722	0.330	4.788	0.254-0.927	0.029
Constant	-4.013	1.156	12.054	-	0.001

NRS: Nutritional risk screening; PNI: Prognostic nutritional index; NLR: Neutrophil-lymphocyte ratio; PLR: Platelet count and lymphocyte count ratio; RR: Relative risk; CI: Confidence interval.