Predictive factors and model validation of post-colon polyp surgery Helicobacter pylori infection

Table 1 Baseline information for modeling and validation cohorts

Sports event		Total population (n = 80)	Modeling queues (n = 56)	Validation queue (n = 24)
Gender [n (%)]	Male	42 (52.50)	30 (53.57)	12 (50.00)
	Female	38 (47.50)	26 (46.43)	12 (50.00)
Age (yr, mean ± SD)		36.15 ± 11.79	36.67 ± 10.00	35.92 ± 13.58
BMI [n (%)]		22.42 ± 3.44	22.20 ± 2.32	22.64 ± 4.55
Movement [n (%)]	< 1 h/wk	38 (47.50)	27 (48.21)	11 (45.83)
	≥ 1 h/wk	42 (52.50)	29 (51.79)	13 (54.17)
Literacy [n (%)]	Primary and below	30 (37.50)	20 (35.71)	10 (41.67)
	Junior high school and secondary school	29 (36.25)	21 (37.50)	8 (33.33)
	Junior college or above	21 (26.25)	15 (26.79)	6 (25.00)
Smoking [n (%)]	Be	33 (41.25)	24 (42.86)	9 (37.50)
	Clogged	45 (56.25)	32 (57.14)	13 (54.17)
Alcohol consumption [n (%)]	Be	44 (55.00)	31 (55.36)	13 (54.17)
	Clogged	34 (42.50)	25 (44.64)	9 (37.50)
History of hypertension [n (%)]	Be	32 (40.00)	22 (39.29)	10 (41.67)
	Clogged	48 (60.00)	34 (60.71)	14 (58.33)
History of diabetes [n (%)]	Be	14 (17.50)	10 (17.86)	4 (16.67)
	Clogged	66 (82.50)	46 (82.14)	20 (83.33)
Number of polyps [n (%)]	An odd one	38 (47.50)	27 (48.21)	11 (45.83)
	Multi- (faceted, ethnic etc.)	42 (52.50)	29 (51.79)	13 (54.17)
Polyp size [n (%)]	< 1 cm	33 (41.25)	23 (41.07)	10 (41.67)
	≥ 1 cm	47 (58.75)	33 (58.93)	14 (58.33)
Polyp site [n (%)]	Proximal	27 (33.75)	19 (33.93)	8 (33.33)
	Far end	25 (31.25)	18 (32.14)	7 (29.17)
	Whole colon	28 (35.00)	19 (33.93)	9 (37.50)
Type of polyp pathology [n (%)]	Adenomatous polyp	35 (43.75)	24 (42.86)	11 (45.83)
	Non-adenomatous polyp	45 (56.25)	32 (57.14)	13 (54.17)
High-risk adenomas [n (%)]	Be	23 (28.75)	16 (28.57)	7 (29.17)
	Clogged	57 (71.25)	40 (71.43)	17 (70.83)
Heavy diet [n (%)]	Be	46 (57.50)	32 (57.14)	1 4 (58.33)
	Clogged	34 (42.50)	24 (42.86)	10 (41.67)

BMI: Body mass index.

Table 2 Comparison of clinical data between Helicobacter pylori-infected and Helicobacter pylori-uninfected groups of patients in the model cohort

Sports event		Hp infection group (n = 37)	Hp uninfected group (n = 19)	χ2 value	P value
Gender [n (%)]	Male	20 (54.05)	10 (52.63)	0.010	0.920
	Female	17 (45.95)	9 (47.37)
Age (yr, mean ± SD)			46.58 ± 3.50	4.788	0.000
BMI [n (%)]			20.37 ± 1.65	5.114	0.000
Movement [n (%)]	< 1 h/wk	18 (48.65)	9 (47.37)	0.008	0.928
	≥ 1 h/wk	19 (51.35)	10 (52.63)
Literacy [n (%)]	Primary and below	16 (43.24)	4 (21.05)	2.348	0.019
	Junior high school and secondary school	15 (40.54)	6 (31.58)
	Junior college or above	6 (16.22)	9 (47.37)
Smoking [n (%)]	Be	16 (43.24)	8 (42.11)	0.007	0.935
	Clogged	21 (56.76)	11 (57.89)
Alcohol consumption [n (%)]	Be	24 (64.86)	7 (36.84)	3.989	0.046
	Clogged	13 (35.14)	12 (63.16)
History of hypertension [n (%)]	Be	15 (40.54)	7 (36.84)	0.072	0.788
	Clogged	22 (59.46)	12 (63.16)
History of diabetes [n (%)]	Be	9 (24.32)	1 (5.26)	1.946	0.163
	Clogged	28 (75.68)	18 (94.74)
Number of polyps [n (%)]	An odd one	17 (45.95)	10 (52.63)	0.225	0.636
	Multi- (faceted, ethnic etc.)	20 (54.05)	9 (47.37)
Polyp size [n (%)]	< 1 cm	15 (40.54)	8 (42.11)	0.013	0.910
	≥ 1 cm	22 (59.46)	11 (57.89)
Polyp site [n (%)]	Proximal	10 (27.03)	9 (47.37)	2.326	0.313
	Far end	13 (35.14)	5 (26.32)
	Whole colon	14 (37.84)	5 (26.32)
Type of polyp pathology [n (%)]	Adenomatous polyp	20 (56.76)	4 (21.05)	5.583	0.018
	Non-adenomatous polyp	17 (27.03)	15 (52.63)
High-risk adenomas [n (%)]	Be	14 (37.84)	2 (10.53)	4.588	0.032
	Clogged	23 (62.16)	17 (89.47)
Heavy diet [n (%)]	Be	25 (67.57)	7 (36.84)	4.839	0.028
	Clogged	12 (32.43)	12 (63.16)

BMI: Body mass index.

Table 3 Univariate analysis of Helicobacter pylori-infected and Helicobacter pylori-uninfected groups

Considerations	B	SE	Wals	P value	OR	95%CI
Age	-0.169	0.049	12.137	0.000	0.844	0.768-0.929
BMI	0.738	0.216	11.708	0.001	2.093	1.371-3.194
Educational attainment	-0.912	0.393	5.383	0.020	0.402	0.186~0.868
Drinking wine	1.152	0.587	3.850	0.050	3.165	1.001-10.004
Types of polyp pathology	1.484	0.652	5.178	0.023	0.227	0.063-0.814
High-risk adenoma	1.644	0.821	4.010	0.045	5.174	1.035-25.852
Heavy diet	1.399	0.596	5.506	0.019	4.052	1.259-13.038

OR: Odds ratio; 95%CI: 95% confidence interval; BMI: Body mass index.

Table 4 Multifactorial analysis of Helicobacter pylori-infected and Helicobacter pylori-uninfected groups

considerations	B	SE	Wals	P value	OR	95%CI
Age	-0.342	0.145	5.574	0.018	0.710	0.535-0.944
BMI	1.222	0.446	7.524	0.006	3.395	1.418-8.130
Types of polyp pathology	-3.760	1.772	4.505	0.034	0.023	0.001-0.750
Constant	-3.798	7.216	0.277	0.599	0.022	-

Table 5 Correlation between different types of pathology and occurrence of Helicobacter pylori infection after colon polyp surgery

		Inflammatory polyp	Hyperplastic polyp	Adenomatous polyp
Helicobacter pylori infection	Correlation coefficient	-0.085	-0.253	0.316
	Sig. (bilateral)	0.532	0.060	0.018