Case Control Study
Copyright ©The Author(s) 2023.
World J Gastrointest Surg. Jul 27, 2023; 15(7): 1354-1362
Published online Jul 27, 2023. doi: 10.4240/wjgs.v15.i7.1354
Table 1 Comparison of baseline data of the four groups

Group A
Group B
Group C
Group D
P value
n22222221
Sex (male/female)14/812/1011/1110/110.663
Age (yr)50.36 ± 5.6251.23 ± 5.4850.64 ± 5.0252.24 ± 5.820.722
Body mass index (kg/m2)22.17 ± 2.5223.64 ± 2.4222.17 ± 2.5222.64 ± 2.410.167
Pathologic tumor stage (I/II/III)10/7/59/7/68/8/69/6/60.996
Gastric cancer tissue type (adenocarcinoma/papillary adenocarcinoma/other)15/4/315/3/414/4/415/2/40.983
Table 2 Comparison of surgical and pathological indices of patients in the four groups

Group A
Group B
Group C
Group D
P value
n22222221
Intraoperative blood loss (mL)120.36 ± 22.67142.64 ± 30.64123.23 ± 33.59139.52 ± 32.840.034
Anastomosis time (min)45.36 ± 3.3259.23 ± 3.4646.55 ± 3.1760.10 ± 3.82< 0.001
Operation time (min)258.73 ± 23.78274.77 ± 24.84260.50 ± 21.73276.33 ± 25.260.026
Maximum diameter of the gastric tumor (cm)2.67 ± 0.522.54 ± 0.452.49 ± 0.522.60 ± 0.480.605
Total lymph node dissection (times)29.27 ± 8.8630.41 ± 8.4328.27 ± 8.9129.81 ± 8.070.865
Table 3 Postoperative recovery of patients in the four groups

Group A
Group B
Group C
Group D
P value
n22222221
Drainage tube Removal time (d)7.82 ± 2.097.68 ± 1.708.41 ± 2.097.76 ± 1.870.590
First fluid diet intake time (d)3.82 ± 0.915.14 ± 1.133.50 ± 1.014.95 ± 1.07< 0.001
First exhaust time (d)3.23 ± 0.534.23 ± 0.753.14 ± 0.564.19 ± 0.81< 0.001
Length of postoperative hospital stay (d)11.73 ± 1.5213.55 ± 1.4411.45 ± 1.7713.43 ± 1.89< 0.001
Table 4 Comparison of QLQ-C30 scores of patients in the four groups after surgery

Group A
Group B
Group C
Group D
n22222221
Physical function76.59 ± 10.4670.01 ± 11.6177.82 ± 11.1674.14 ± 12.41
Role function85.41 ± 10.0183.45 ± 13.4377.82 ± 11.7384.24 ± 10.60
Emotional function72.59 ± 9.4969.95 ± 12.1373.05 ± 11.3270.67 ± 10.80
Cognitive function61.68 ± 9.6464.36 ± 11.5463.09 ± 12.0165.90 ± 10.63
Social function72.36 ± 13.5677.77 ± 11.3378.41 ± 13.9076.9 ± 13.03
General health function56.32 ± 14.4161.55 ± 10.0559.32 ± 9.5561.10 ± 12.73
Fatigue function40.45 ± 6.7140.95 ± 8.3945.09 ± 5.9439.10 ± 8.42
Table 5 Comparison of QLQ-C30 scores of patients in the four groups after surgery

Group A
Group B
Group C
Group D
n22222221
Nausea and vomiting11.64 ± 3.409.91 ± 3.5712.05 ± 3.6210.01 ± 4.03
Pain14.91 ± 3.7814.23 ± 4.4414.32 ± 4.1115.62 ± 3.85
Panting20.68 ± 4.5922.41 ± 4.5822.45 ± 4.5921.33 ± 4.50
Insomnia21.59 ± 5.5421.27 ± 4.9522.09 ± 4.3020.19 ± 4.24
Appetite14.77 ± 4.9615.77 ± 4.6416.64 ± 5.4718.24 ± 5.08
Constipation19.77 ± 4.3019.77 ± 5.0521.18 ± 3.6219.57 ± 3.94
Diarrhea24.09 ± 5.8623.32 ± 4.9521.95 ± 5.0223.10 ± 4.58
Financial difficulties12.18 ± 3.9113.14 ± 2.9012.45 ± 3.4911.48 ± 3.63
Table 6 Comparison of QLQ-STO22 scores of patients in the four groups after surgery

Group A
Group B
Group C
Group D
n22222221
Deglutition5.55 ± 1.475.01 ± 1.385.59 ± 1.894.76 ± 1.67
Pain8.18 ± 1.877.36 ± 1.768.86 ± 2.308.62 ± 2.27
Reflux11.68 ± 3.1111.82 ± 2.6312.18 ± 2.1111.05 ± 2.99
Intake10.73 ± 2.1010.18 ± 1.8210.68 ± 2.1010.14 ± 1.62
Anxiety16.41 ± 3.2316.27 ± 3.0615.86 ± 2.8316.62 ± 3.28
Xerostomia5.05 ± 0.954.73 ± 0.944.91 ± 0.924.57 ± 0.87
Sapidity6.32 ± 2.065.68 ± 1.675.91 ± 1.546.14 ± 1.77
Soma7.18 ± 1.826.55 ± 1.996.64 ± 1.897.52 ± 1.97
Alopecia3.77 ± 0.753.73 ± 0.834.14 ± 0.713.90 ± 0.71
Table 7 Recent postoperative complications of patients in the four groups

Group A
Group B
Group C
Group D
P value
n22222221
Anastomotic leakage0100
Anastomotic stricture1112
Abdominal infection1111
Dumping syndrome1212
Emptying dysfunction2221
Incidence rate (%)5 (22.73)7 (31.82)5 (22.73)6 (28.57)0.876