Prognostic value of preoperative immune-nutritional scoring systems in remnant gastric cancer patients undergoing surgery

Table 1 Clinical characteristics of patients and three immune-nutritional score systems

Characteristics	Immune–nutritional score systems
	Values (n = 54)	PNI (n = 27/27)	P value	CONUT (n = 34/20)	P value	NPS (n = 32/22)	P value
Age (years)			1.000		0.368		0.047
< 70	26	13/13		18/8		19/7
≥ 70	28	14/14		16/12		13/15
Gender			1.000		0.713		0.216
Male	42	21/21		27/15		23/19
Female	12	6/6		7/5		9/3
Primary tumor size			0.790		0.581		1.000
≤ 3 cm	27	13/14		18/9		16/11
> 3 cm	27	14/13		16/11		16/11
Gross type			0.412		0.313		0.386
Non-ulcerative type	21	12/9		15/6		14/7
Ulcerative type	33	15/18		19/14		18/15
Differentiation			0.285		0.449		0.189
Well/Moderate	28	16/12		19/9		19/9
Poor	26	11/15		15/11		13/13
T stage			0.588		0.519		0.984
T1/T2	22	12/10		15/7		13/9
T3/T4	32	15/17		19/13		19/13
Lymph node metastasis			0.106		0.449		0.445
No	28	17/11		19/9		18/10
Yes	26	10/16		15/11		14/12
cTNM status			0.282		0.538		0.075
I/II	30	17/13		20/10		21/9
III	24	10/14		14/10		11/13

The number of cases, low risk cases/high risk cases were shown, p-value indicated the significance of different immune-nutritional risk between the patients with different clinical characteristics. PNI: Prognostic nutritional index; CONUT: Controlled nutritional status; NPS: Naples prognostic score; cTNM: Clinical Tumor-Node-Metastasis.

Table 2 Cox regression analysis of overall survival

Characteristic	OS
	HR	95%CI	P value
Age (years)			0.500
< 70	1.000	0.605-2.796
≥ 70	1.301
Gender			0.451
Male	1.000	0.261-1.1.816
Female	0.689
Primary tumor size			0.926
≤ 3 cm	1.000	0.479-2.242
> 3 cm	1.037
Gross type			0.014
Non-ulcerative type	1.000	1.285-8.932
Ulcerative type	3.388
Differentiation			0.032
Well/Moderate	1.000	1.083-5.629
Poor	2.469
T stage			0.289
T1/T2	1.000	0.671-3.823
T3/T4	1.601
Lymph node metastasis			<0.001
No	1.000	1.963-10.472
Yes	4.534
cTNM stage			0.001
I/II	1.000	1.734-9.117
III	3.976
PNI group			0.002
Low risk	1.000	1.724-10.030
High risk	4.158
CONUT group			0.039
Low risk	1.000	1.041-4.666
High risk	2.204
NPS group			< 0.001
Low risk	1.000	1.879-9.425
High risk	4.208

PNI: Prognostic nutritional index; CONUT: Controlled nutritional status; NPS: Naples prognostic score; cTNM: Clinical Tumor-Node-Metastasis; OS: Overall survival; HR: Hazard ratio; CI: Confidence interval.