Multidisciplinary diagnosis and treatment nutritional support intervention for gastrointestinal tumor radiotherapy: Impact on nutrition and quality of life

Table 1 Characteristics of participants

Items		MDT group (n = 60)	Control group (n = 60)	Statistical value	P value
Age (yr)	≤ 65	55.58 ± 1.09	53.66 ± 1.05	1.272	0.209
	> 65	73.48 ± 0.77	73.62 ± 0.86	0.119	0.996
Sex	Male	14	16	0.067	0.796
	Female	15	15
Simultaneous chemotherapy treatments	Yes	11	12	0.071	0.791
	No	19	18
Tumor type	Stomach cancer	5	6	0.292	0.962
	Cancer of the esophagus	7	8
	Intestinal cancer	12	11
	Other cancer	6	5
Lymph node metastasis	Yes	14	13	0.067	0.795
	No	16	17

MDT: Multidisciplinary diagnosis and treatment.

Table 2 Differences between the multidisciplinary diagnosis and treatment and control groups in albumin/total protein

	ALB		TP
	Before	After	Before	After
MDT group	39.83 ± 0.55	34.74 ± 0.48a	66.77 ± 0.93	62.16 ± 0.70a
Control group	39.65 ± 0.44	37.14 ± 0.52a	67.66 ± 0.82	66.10 ± 1.00a
H/t	-0.134	3.066	0.705	3.021
P value	0.893	0.002	0.481	0.003

^aP < 0.05, difference compared with that before treatment.

ALB: Albumin; TB: Total protein; MDT: Multidisciplinary diagnosis and treatment.

Table 3 Differences between multidisciplinary diagnosis and treatment and control groups in transferrin/hemoglobin

	TRF		Hb
	Before	After	Before	After
MDT group	275.29 ± 2.03	34.74 ± 0.48a	139.51 ± 1.10	121.68 ± 1.12a
Control group	271.27 ± 0.44	37.14 ± 0.52a	137.55 ± 1.11	130.83 ± 1.55a
H	-1.066	2.569	-1.148	3.867
P value	0.286	0.010	0.251	0.000

^aP < 0.05, difference compared with that before treatment.

TRF: Transferrin; Hb: Hemoglobin; MDT: Multidisciplinary diagnosis and treatment.

Table 4 The difference in the Patient-Generated Subjective Global Assessment score compared between the multidisciplinary diagnosis and treatment and control groups before and after treatment

	Before PG-SGA		After PG-SGA
	Well-nourished	Malnourished	Well-nourished	Malnourished
MDT group	7	23	13	17
Control group	8	22	4	26
Z		0.089		6.648
P value		0.766		0.010

Before Patient-Generated Subjective Global Assessment (PG-SGA) refers to before-patient treatment; after PG-SGA refers to after-patient treatment. PG-SGA: Patient-Generated Subjective Global Assessment; MDT: Multidisciplinary diagnosis and treatment.

Table 5 Quality of life difference between the multidisciplinary diagnosis and treatment and control groups

		MDT group	Control group	H/t	P value
Total score	Before	29.57 ± 0.59	30.53 ± 0.57	1.259	0.208
	After	47.90 ± 1.37	40.30 ± 1.03	3.814	0.000
Functional scale
Somatic function	Before	68.96 ± 0.68	67.87 ± 1.40	-0.126	0.900
	After	83.23 ± 0.58	77.40 ± 0.96	4.057	0.000
Role function	Before	62.06 ± 1.74	59.93 ± 0.74	-0.051	0.959
	After	72.77 ± 1.01	69.03 ± 1.32	2.245	0.025
Emotional function	Before	47.87 ± 0.78	46.60 ± 0.67	1.235	0.222
	After	67.03 ± 1.11	55.63 ± 0.87	5.729	0.000
Cognitive function	Before	49.56 ± 0.35	49.07 ± 0.31	-1.205	0.228
	After	65.27 ± 1.21	62.90 ± 1.09	1.37	0.168
Social function	Before	53.53 ± 0.99	52.10 ± 0.88	-1.052	0.293
	After	63.13 ± 1.16	62.67 ± 1.04	0.393	0.695
Symptom scale
Pain score	Before	69.93 ± 1.72	73.23 ± 1.67	1.442	0.149
	After	51.80 ± 1.35	64.33 ± 1.91	-4.492	0.000
Fatigue score	Before	73.63 ± 1.47	72.10 ± 1.28	1.220	0.204
	After	47.53 ± 1.58	52.70 ± 1.40	-2.020	0.043
Nausea and vomiting score	Before	54.16 ± 0.95	55.53 ± 0.82	1.246	0.213
	After	34.57 ± 0.51	45.97 ± 1.29	8.193	0.000

MDT: Multidisciplinary diagnosis and treatment.