Retrospective Study
Copyright ©The Author(s) 2021.
World J Gastrointest Surg. Dec 27, 2021; 13(12): 1696-1707
Published online Dec 27, 2021. doi: 10.4240/wjgs.v13.i12.1696
Table 1 Preoperative characteristics before and after propensity score matching, according to the procedure
Before PSM (n: 77)
After PSM (n: 52)
RFA (n: 40)
Surgery (n: 37)
P value
RFA (n: 26)
Surgery (n: 26)
P value
Male, n (%)28 (70)27 (73)0.8017 (65)16 (62)1.0
Age (yr) median (range)74.5 (70-87)74.98 (70-83)0.8075 (70-81)74.26 (70-81)0.43
BMI (kg/cm²) median (range)26.7 (19-51)26.7 (22-36)0.9026.7 (19-51)26.7 (22-36)0.48
Comorbidity ≥ 2, n (%)23 (57)14 (38)0.1012 (46)10 (40)0.78
Cause of cirrhosis, n (%)0.300.71
Hepatitis C virus, n (%)21 (53)19 (50)16 (61)16 (61)
Hepatitis B virus, n (%)5 (12)10 (27)4 (15)6 (23)
Alcohol, n (%)6 (15)4 (12)3 (12)1 (4)
Others, n (%)8 (20)4 (11)3 (12)3 (12)
F4 cirrhosis, n (%)33 (82)19 (51)0.0122 (85)12 (46)0.01
ASA score, n (%)0.050.35
I/II, n (%)11 (28)19 (51)10 (40)11 (42)
III/IV, n (%)29 (72)18 (49)16 (61)15 (58)
Preoperative blood tests median (range)
Bilirubin (µmol/L) median (range)1 (1-1.1)1 (1-2)0.551 (1-1.1)1 (1-1)0.90
Platelet count × 109/L median (range)118 (52-380)173 (55-387)0.01137 (69-380)183 (55-340)0.06
INR median (range)1 (1-2)1 (1-2)0.401 (1-1.2)1 (1-2)0.06
AFP (mg/mL) median (range)5 (1-1988)12.5 (2-3900)0.146.5 (1-1988)7 (2-3900)0.64
Child-Pugh, n (%)0.200.06
A37 (93)30 (81)26 (100)21 (81)
B3 (7)7 (19)0 (0)5 (19)
MELD median (range)8 (6-15)6 (6-16)0.018 (6-15)7 (6-16)0.23
Tumors size (mm) median (range)23 (10-30)29 (12-30)0.0220.5 (10-30)23 (15-30)0.08
Tumor locations, n (%)0.100.45
4a3 (7)3 (8)2 (8)2 (8)
78 (20)17 (46)4 (15)9 (34)
8 23 (58)14 (38)17 (65)13 (50)
7-8 6 (15)3 (8)3 (12)2 (8)
Histological proven, n (%)7 (17)8 (22)0.806 (23)8 (31)0.75
Table 2 Perioperative characteristics before and after propensity score matching, according to the procedure
Before PSM (n: 77)
After PSM (n: 52)
RFA (n: 40)
Surgery (n: 37)
P value
RFA (n: 26)
Surgery (n: 26)
P value
Operative time (min) median (range)23.5 (5-55)260 (120-600)< 0.0120 (5-26)165 (120-383)< 0.01
Blood transfusion, n (%)3 (7)7 (19)0.203 (12)5 (19)0.70
Postoperative complications, n (%)9 (22)16 (43)0.095 (19)14 (54)0.02
Dindo-Clavien classification, n (%)
I-II9 (22)11 (30)0.605 (19)10 (40)0.20
III-IV0 (0)5 (13)0.020 (0)2 (8)0.50
Type of complications, n (%)
Liver failure0 (0)2 (5)0.220 (0)2 (8)0.50
Ascites0 (0)4 (11)0.050 (0)4 (15)0.11
Biliary leakage0 (0)1 (3)0.500 (0)1 (4)1
Hemorrhage1 (2)2 (5)0.601 (4)1 (4)1.0
Systemic infection0 (0)4 (11)0.050 (0)4 (15)0.11
Intra-abdominal abscess0 (0)2 (5)0.230 (0)1 (4)1.0
Wound infection0 (0)0 (0)0 (0)0 (0)
Portal thrombosis0 (0)0 (0)0 (0)0 (0)
Pulmonary3 (7)3 (8)11 (4)3 (12)0.61
Cardiac1 (2)2 (5)0.600 (0)2 (8)0.50
Renal1 (2)3 (8)0.351 (4)2 (8)1.0
Reoperation, n (%)0 (0)0 (0)0 (0)0 (0)
Postoperative treatment, n (%)0 (0)2 (5)0.230 (0)1 (4)1.0
Length of hospital stay (d) median (range)2 (1-15)6 (2-203)< 0.013 (1-9)7.5 (2-203)< 0.01
90 d mortality, n (%)2 (5)2 (5)1.02 (8)2 (8)1.0
Recurrence, n (%)21 (52)15 (40)0.4012 (46)11 (42)1.0

  • Citation: Delvecchio A, Inchingolo R, Laforgia R, Ratti F, Gelli M, Anelli MF, Laurent A, Vitali G, Magistri P, Assirati G, Felli E, Wakabayashi T, Pessaux P, Piardi T, di Benedetto F, de'Angelis N, Briceño J, Rampoldi A, Adam R, Cherqui D, Aldrighetti LA, Memeo R. Liver resection vs radiofrequency ablation in single hepatocellular carcinoma of posterosuperior segments in elderly patients. World J Gastrointest Surg 2021; 13(12): 1696-1707
  • URL: https://www.wjgnet.com/1948-9366/full/v13/i12/1696.htm
  • DOI: https://dx.doi.org/10.4240/wjgs.v13.i12.1696