Newly developed self-expandable Niti-S MD colonic metal stent for malignant colonic obstruction

doi:10.4240/wjgs.v12.i4.138

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 12, Issue 4

This Article

Academic Content and Language Evaluation of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (6181)

All Articles published online

The chart showing PDF series, WORD series, HTML series, Figures (1-4) series, Tables (1-3) series.

Item

Count

PDF

354

WORD

161

HTML

3817

Figures (1-4)

379

Tables (1-3)

239

Sum=4950

Publishing Process of This Article

The chart showing Browse series, Download series.

Item

Count

Browse

591

Download

640

Sum=1231

Apr 27, 2020 (publication date) through Apr 20, 2024

Times Cited of This Article

Times Cited (8)

Journal Information of This Article

Publication Name

World Journal of Gastrointestinal Surgery

ISSN

1948-9366

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

World J Gastrointest Surg. Apr 27, 2020; 12(4): 138-148
Published online Apr 27, 2020. doi: 10.4240/wjgs.v12.i4.138

Table 1 Patients’ demographics and clinical characteristics in each group

	Group W (n = 37)	Group N (n = 53)	Group MD (n = 20)	Total (n = 110)
Patients’ characteristics
Age (yr, mean ± SD)	71.4 ± 11.8	74.3 ± 13.6	73.7 ± 9.6	73.5 ± 12.5
Male/Female	18/19	28/25	15/5	61/49
PS score (mean ± SD)	1.6 ± 1.2	1.9 ± 1.2	2.3 ± 1.0	1.9 ± 1.2
Therapeutic intent
BTS	19/37 (51.4%)	32/53 (60.4%)	10/20 (50%)	61/110 (55.5%)
PAL	18/37 (48.6%)	21/53 (39.6%)	10/20 (50%)	49/110 (44.5%)
Tumor characteristics
Obstruction/tumor site
Right colon	8/37 (21.6%)	14/53 (26.4%)	6/20 (30%)	28/110 (25.4%)
Left colon	27/37 (73.0%)	38/53 (71.7%)	10/20 (50%)	75/110 (68.2%)
Rectum	2/37 (5.4%)	1/53 (1.9%)	4/20 (20%)	7/110 (6.4%)
Etiology of colorectal obstruction
Primary colorectal cancer	30/37 (81.1%)	49/53 (92.5%)	13/20 (65%)	92/110 (83.6%)
Metastatic lesion	7/37 (18.9%)	4/53 (7.5%)	7/20 (35%)	18/110 (16.4%)
Noncancerous stenosis	0/37 (0%)	0/53 (0%)	0/20 (0%)	0/110 (0%)
Stenosis length [cm, median (range)]	5.0 (2.0-13.0)	5.0 (2.0-11.0)	6.2 (2.5-11.5)	5.0 (2.0-13.0)

BTS: Bridge-to-surgery; PAL: Palliative.

Table 2 Outcomes in each stent group, Group W, Group N, and Group MD

	Group W	Group N	Group MD	Total
Technical success rate	37/37 (100%)	53/53 (100%)	20/20 (100%)	110/110 (100%)
Stent length
6 cm	24/37 (64.9%)	12/53 (22.6%)	3/20 (15%)	39/110 (35.5%)
8 cm	NA	17/53 (32.1%)	7/20 (35%)	24/110 (21.8%)
9 cm	11/37 (29.7%)	NA	NA	11/110 (10.0%)
10 cm	NA	18/53 (34.0%)	6/20 (30%)	24/110 (21.8%)
12 cm	2/37 (5.4%)	6/53 (11.3%)	4/20 (20%)	12/110 (10.9%)
Stent diameter
18 mm	NA	6/53 (11.3%)	NA	6/110 (5.5%)
22 mm	30/37 (81.1%)	47/53 (88.7%)	20/20 (100%)	97/110 (88.2%)
25 mm	7/37 (18.9%)	NA	NA	7/110 (6.3%)
Procedure time (min, mean ± SD)	32.6 ± 14.0	33.6 ± 23.7	31.3 ± 11.2	33.0 ± 19.1
Clinical success rate	33/37 (89.2%)	51/53 (96.2%)	20/20 (100%)	104/110 (94.5%)
BTS	19/19 (100%)	31/32 (96.9%)	10/10 (100%)	60/61 (98.4%)
PAL	14/18 (77.8%)	20/21 (95.2%)	10/10 (100%)	44/49 (89.8%)
CROSS before stent placement (mean ± SD)	1.6 ± 1.3	1.2 ± 1.0	1.4 ± 0.9	1.4 ± 1.1
0	12/37 (32.5%)	10/53 (18.9%)	3/20 (15%)	25/110 (22.7%)
1	8/37 (21.6%)	32/53 (60.4%)	9/20 (45%)	49/110(44.6%)
2	3/37 (8.1%)	4/53 (7.5%)	5/20 (25%)	12/110 (10.9%)
3	13/37 (35.1%)	5/53 (9.4 %)	3/20 (15%)	21/110 (19.1%)
4	1/37 (2.7%)	2/53 (3.8%)	0/20 (0%)	3/110 (2.7%)
CROSS after stent placement (mean ± SD)	3.8 ± 0.8^a	3.8 ± 0.7^a	3.8 ± 0.5^a	3.8 ± 0.7^a
0	0/37 (0%)	0/53 (0%)	0/20 (0%)	0/110 (0%)
1	3/37 (8.1%)	2/53 (3.8%)	0/20 (0%)	5/110(4.6%)
2	0/37 (0%)	2/53 (3.8%)	1/20 (5.0%)	3/110 (2.7%)
3	0/37 (0%)	0/53 (0 %)	2/20 (10%)	2/110 (1.8%)
4	34/37 (91.9%)	49/53 (92.4%)	17/20 (85%)	110/110 (90.9%)

The CROSS score after stent placement was significantly higher than one before treatment,

^aP < 0.01. BTS: Bridge-to-surgery; PAL: Palliative; CROSS: ColoRectal Obstruction Scoring System; NA: Not available.

Table 3 Early and late adverse events

	Group W	Group N	Group MD	Total
Early (≤ 7 d)
Perforations	0/37 (0%)	2/53 (3.8%)¹	0/20 (0%)	2/110 (1.8%)
Bleeding	0/37 (0%)	0/53 (0%)	0/20 (0%)	0/110 (0%)
Poor expansion	1/37 (2.7%)	0/53 (0%)	0/20 (0%)	1/110 (0.9%)
Abdominal pain	3/37 (8.1%)	0/53 (0%)	0/20 (0%)	3/110 (2.7%)
Stent occlusion	0/37 (0%)	0/53 (0%)	0/20 (0%)	0/110 (0%)
Fever	1/37 (2.7%)	0/53 (0%)	0/20 (0%)	1/110 (0.9%)
Late (> 7 d)
Perforations	4/36 (11.1%)^a²	0/51 (0%)^a	0/20 (0%)	4/107 (3.7%)
Bleeding	0/36 (0%)	0/51 (0%)	0/20 (0%)	0/107 (0%)
Stent migration	0/36 (0%)	0/51 (0%)	0/20 (0%)	0/107 (0%)
Abdominal pain	0/36 (0%)	0/51 (0%)	0/20 (0%)	0/107 (0%)
Stent occlusion	1/36 (2.8%)	2/51 (3.9%)	0/20 (0%)	3/107 (2.8%)

¹Perforation occurred due to obstructive colitis in all two cases;

²All four cases were stent-related perforation.

^aP < 0.05.

Citation: Miyasako Y, Kuwai T, Ishaq S, Tao K, Konishi H, Miura R, Sumida Y, Kuroki K, Tamaru Y, Kusunoki R, Yamaguchi A, Kouno H, Kohno H. Newly developed self-expandable Niti-S MD colonic metal stent for malignant colonic obstruction. World J Gastrointest Surg 2020; 12(4): 138-148
URL: https://www.wjgnet.com/1948-9366/full/v12/i4/138.htm
DOI: https://dx.doi.org/10.4240/wjgs.v12.i4.138