Male gender and increased body mass index independently predicts clinically relevant morbidity after spleen-preserving distal pancreatectomy

Table 1 Demographic, clinical, bioumoral, intraoperative and pathology data of 41 patients with spleen-preserving distal pancreatectomy: A comparative analysis between patients with and without clinically relevant postoperative complications

Parameter	All patients	No complications(33 patients)	Clinically relevant complications(8 patients)	P value
Male gender	12 (29.3%)	7 (21.2%)	5 (62.5%)	0.031
Age, yr	41 (18–76)	39 (18–76)	51 (34–66)	0.0672
Charlson comorbidity index	0 (0–4)	0 (0–4)	1.5 (0–3)	0.1572
Body mass index, kg/m2	25 (19–42)	24 (19–37)	34.5 (24–42)	0.0022
Overweight and obesity	22 (53.6%)	15 (45.4%)	7 (87.5%)	0.0491
Overweight	8 (19.5%)	7 (21.2%)	1 (12.5%)	11
Obesity	14 (34.1%)	8 (24.2%)	6 (75%)	0.0121
Diabetes mellitus	1 (2.4%)	0	1 (12.5%)	0.1951
Chronic pancreatitis	6 (14.6%)	5 (15.1%)	1 (12.5%)	11
Preoperative leucocytes number3, /μL	7700 (4900-15300)	7700 (4900–15300)	7300 (5200–9200)	0.9612
Preoperative neutrophil number3, /μL	4900 (2800–13200)	4900 (2800–13200)	4050 (3500–6400)	0.7592
Preoperative lymphocyte number3, /μL	1800 (1000–3300)	1600 (1000–3300)	2200 (1100–2900)	0.2912
Preoperative neutrophil-to-lymphocyte ratio3	2.9 (1.2–8.4)	2.9 (1.2–8.4)	2.2 (1.6–5.8)	0.1372
Preoperative platelet number3, /μL	262500 (161000–464000)	264000 (161000–410000)	258000 (170000–464000)	0.7352
Preoperative platelet-to-lymphocyte ratio3	134 (55.4–372.7)	134 (55.4–372.7)	141.9 (85–372.7)	0.5502
ASA score 3	6 (14.6%)	4 (12.1%)	2 (25%)	0.5771
Minimally invasive approach	6 (14.6%)	4 (12.1%)	2 (25%)	0.5771
Soft pancreas texture	35 (85.3%)	28 (84.8%)	7 (87.5%)	11
Associated procedures	5 (12.2%)	4 (12.1%)	1 (12.5%)	11
Operative time, min	150 (70–330)	150 (70–320)	185 (120–330)	0.0672
Estimated blood loss, mL	150 (50–600)	150 (50–600)	175 (50–300)	0.5502
Intraoperative blood transfusions	1 (2.4%)	1 (3%)	0	11
Tumor diameter, cm	3.5 (0.4–14)	3 (0.4–14)	2.75 (0.4–3.5)	0.0602
Length of resected pancreas, cm	9 (6–12)	9 (6–12)	8.5 (8–12)	0.7842
Malignant pathology	4 (2.4%)	3(9.1%)	1 (12.5%)	11
Neuroendocrine pathology	18	11	7	0.0131

¹Fisher’s exact test (two-tailed);

²Mann-Whitney test (two-tailed);

³Assessed no more than one week prior to surgery. ASA: American Society of Anesthesiologists.