Stercoral perforation of the cecum: A case report

Abstract

BACKGROUND

With less than 90 reported cases to date, stercoral perforation of the colon is a rare occurrence. Stercoral ulceration is thought to occur due to ischemic pressure necrosis of the bowel wall, which is caused by the presence of a stercoraceous mass. To underscore this urgent surgical situation concerning clinical presentation, surgical treatment, and results, we present the case of a 66-year-old man with a stercoral perforation.

CASE SUMMARY

A 66-year-old man with a history of hypertension, hyperlipidemia, and gout presented at the emergency department with lower abdominal pain and a low-grade fever lasting for a few hours. Abdominal computed tomography indicated a suspected bezoar (approximately 7.6 cm) in the dilated cecum, accompanied by pericolic fat stranding, mild proximal dilatation of the ileum, pneumoperitoneum, and minimal ascites. Intraoperatively, feculent peritonitis with isolated cecal perforation were observed. Consequently, a right hemicolectomy with peritoneal lavage was performed. A histopathological examination supported the intraoperative findings.

CONCLUSION

In stercoral perforations, a diagnosis should be diligently pursued, especially in older adults, and prompt surgical intervention should be implemented.

Key Words: Acute abdomen; Colectomy; Peritoneal lavage; Pneumoperitoneum; Bezoars; Case report

Core Tip: Spontaneous perforations are classified as either stercoral or idiopathic based on underlying etiologic and pathologic factors. In this case, the operative findings and histopathology report led us to conclude that the perforation was stercoral. This perforation is characterized by a rounded or ovoid-shaped defect with underlying necrotic and inflammatory edges in the absence of significant injuries, obstructions, tumors, and diverticulosis. This condition is commonly observed in chronically ill patients at a rate of 47% in the sigmoid colon and 30% in the rectosigmoid colon. In this manuscript, we present a rare case of bezoar-induced stercoral perforation of the cecum.

INTRODUCTION

With less than 90 reported cases to date, stercoral perforation of the colon is a rare occurrence. Stercoral ulceration is thought to occur due to ischemic pressure necrosis of the bowel wall, which is caused by the presence of a stercoraceous mass[1]. To underscore this urgent surgical situation concerning clinical presentation, surgical treatment, and results, we present the case of a 66-year-old man with a stercoral perforation.

CASE PRESENTATION

Chief complaints

A 66-year-old man presented at the emergency department with a 4-h history of lower abdominal and epigastric pain with low-grade fever.

History of present illness

The patient had a normal bowel movement at around 6 am on the day of presentation, then 4 h later he developed abdominal pain in the lower abdomen that increased in intensity and extended to the epigastric area. The pain was accompanied by multiple bowel movements, without nausea or vomiting. He presented to the hospital four hours after the abdominal pain started with lower abdominal pain.

History of past illness

The patient had a history of hypertension, hyperlipidemia, and gout, and regularly visited the cardiology outpatient department for follow-up and maintenance medication. The patient had no history of rectal bleeding, anorexia, or weight loss. Seven years before presentation, the patient underwent a colonoscopy, which revealed no abnormal mucosal or mass lesions up to the ileocecal valve.

Personal and family history

The patient has a history of cigarette smoking, averaging 1-1.5 packs per day for decades. Additionally, he occasionally consumed alcohol socially. Regarding family history, his mother had a history of hypertension and diabetes mellitus.

Physical examination

On physical examination, the patient was conscious and alert. His vital signs were: Body temperature, 36.2 degree Celcius; pulse, 96 beats per minute; blood pressure, 142/82 mmHg. Examination of the abdomen demonstrated rebound tenderness in the right lower quadrants and suprapubic area upon palpation, normal bowel sounds, no tympanic sounds, and no Murphy’s sign. A digital rectal examination revealed traces of stool with a minimal amount of gross blood. No masses were palpable.

Laboratory examinations

A complete blood count showed a white blood cell count of 18.05 × 10⁹/L and a haemoglobin level of 14.7 gm/dL. Other laboratory investigations showed normal results.

Imaging examinations

A plain radiograph of the kidneys, ureters, and bladder revealed a focal lesion in the right lower quadrant of the abdomen (Figure 1). Further imaging via an abdominal computed tomography scan showed a suspected bezoar (approximately 7.6 cm in diameter) in the dilated cecum accompanied by pericolic fat stranding, mild proximal dilatation of the ileum, pneumoperitoneum, and minimal ascites (Figure 2A and B).

Figure 1 Plain radiograph of the patient’s kidneys, ureters, and bladder. The kidneys, ureters, and bladder radiograph displaying a focal lesion in the right lower quadrant of the patient’s abdomen.

Figure 2 Abdominal computed tomography imaging of the patient’s abdomen. A: A suspected bezoar (approximately 7.6 cm) was seen in the dilated cecum (arrow); B: Pericolic fat stranding, mild proximal dilatation of the ileum, pneumoperitoneum and minimal ascites accompanied this lesion.

FINAL DIAGNOSIS

Spontaneous cecal perforation, status post right hemicolectomy on admission to the hospital, status post wound debridement with rectus abdominis flap on post-operative day 12.

TREATMENT

The intravenous antibiotics flomoxef and metronidazole, were administered. A decision was made to perform exploratory laparotomy, during which a rounded perforation (7 cm × 5 cm in diameter) of the cecum was found (Figure 3A). Upon dissection, the cecal wall was found to be thin, without any obvious tumorous lesions on the mucosa (Figure 3B). Seropurulent fluid was present in the peritoneal cavity (Figure 3C) with fecal contamination (Figure 3D). The bezoar extracted from the dilated cecum was 9 centimeters in diameter (Figure 3E). Consequently, a right hemicolectomy with peritoneal lavage was performed. Histopathological examination revealed a grossly rounded cecal perforation with ischemic necrosis (Figure 4A). Microscopically, the mucosa around the perforation exhibited acute transmural inflammatory cell infiltration and fibroblast proliferation (Figure 4B). Remarkable ischemic necrosis with crypt loss was observed.

Figure 3 Intraoperative photographs of gross findings. A: A rounded perforation (7 cm × 5 cm in diameter) of the cecum was intraoperatively noted; B: The cecum was notably thin without any obvious tumorous lesions on the mucosa (as marked); C: Seropurulent fluid was freely present in the peritoneal cavity; D: Fecal contamination was observed in the peritoneal cavity; E: The bezoar extracted from the dilated cecum.

Figure 4 Gross and histopathological examination of the cecal specimen. A: A grossly rounded cecal perforation with ischemic necrosis was observed; B: Microscopically, the muscle layers show lymphoplasma cell infiltration with crypt effacement and hemorrhage.

OUTCOME AND FOLLOW-UP

Postoperatively, the patient recovered from brief atelectasis. However, the wound did not respond well to local treatment with an aqua beta-iodine dressing. Fascial dehiscence occurred with bowel exposure. Therefore, wound debridement was performed using a rectus abdominis flap on post-operative day 12. After the operation, oral feeding was gradually advanced, and the patient tolerated it well. Subsequently, he was discharged in stable condition and followed up in our outpatient clinic.

DISCUSSION

Spontaneous cecal perforation is the sudden perforation of a previously clinically healthy colon in the absence of an underlying disease or injury. To date, fewer than 100 cases have been reported in the literature[2]. In spontaneous perforations, the mean age of affected patients is 65 years. Furthermore, men are more susceptible to perforation, with a ratio of 2:1 in older adult men and women, respectively[3]. Mortality rates associated with cecal perforation are high, ranging from 30% to 72%[4]. The prognosis of spontaneous cecal perforation is influenced by various factors, such as the timing of perforation, the extent of peritoneal contamination, and the timeliness of intervention.

In 1894, Berry classified spontaneous perforations as either stercoral or idiopathic. This classification is based on underlying etiological and pathological factors[5]. Maurer et al[6] established guidelines for identifying stercoral perforation according to the defect’s form, size, its proximity to the mesentery, and the existence of fecalomas poking through the defect. At a microscopic level, pressure-induced necrosis or ulcer surrounded by chronic inflammatory response are observed near the perforation site. In this case, operative findings and histopathology report led us to conclude that the perforation was of the stercoral type. Stercoral perforation is characterized by a rounded or ovoid-shaped defect with underlying necrotic and inflammatory edges in the absence of significant injuries, obstructions, tumors, and diverticulosis[6]. This condition is commonly observed in chronically ill patients. The increase in intraluminal and intra-abdominal pressure during defecation contributes to its etiology[7]. Stercoral perforation is more frequently observed in the sigmoid colon in 47% of cases and the rectosigmoid colon in 30% of cases[8]. In other parts of the colon, it was observed in 33% of cases. However, our patient did not have a history of a significant change of bowel habits and a colonoscopy conducted 7 years prior reported no abnormal mucosal or mass lesions up to the ileocecal valve. According to the intraoperative findings, bezoar-induced perforation is the most reasonable cause.

A bezoar is a firm, solid, enduring foreign object found in the gastrointestinal tract. They can be found in various parts of the gastrointestinal tract, such as the esophagus and colon. Four distinct types of bezoars have been identified based on their originating material: Phytobezoars, trichobezoars, concretions, and pharmacobezoars[9]. None of these described causes seemed to match this patient’s condition. In a retrospective analysis study, alcohol consumption, hypertension, and diabetes were reported to serve as risk factors for bezoars[10]. Therefore, further investigation may be necessary to identify the specific reason of bezoar formation in this case.

Idiopathic perforation occurs because of the asymmetrical distribution of intraluminal pressure at the pelvic-rectal angle in the absence of obviously impacted stool or any identifiable cause of perforation[11]. The exact cause of spontaneous cecal perforation is unclear; however, it has been reported to be associated with certain conditions including hypothyroidism, intestinal hypomotility, chronic constipation, and fecal impaction[12]. Notably, steroids and nonsteroidal anti-inflammatory drugs inhibit cyclo-oxygenase enzymes, resulting in a subsequent reduction in protective prostaglandins[13]. Fecal impaction induced by drugs such as opiates, antacids, codeine, amitriptyline, and tranquilizers is becoming more prevalent and could lead to spontaneous cecal perforation.

CONCLUSION

Cecal perforation occurring spontaneously is an uncommon occurrence linked with heightened morbidity and mortality rates. Irrespective of the surgical approach, detecting it early and swiftly resorting to surgical intervention are key tactics linked with better results. Hence, it’s imperative to strive for a timely diagnosis, particularly in the elderly, and promptly initiate surgical measures.

ACKNOWLEDGEMENTS

The authors wish to acknowledge the assistance of the people at the Department of Surgery, Tri-Service General Hospital Songsang Branch. This report would not have been possible without their efforts in data collection and interprofessional collaboration in treating this patient.