Blastomas of the digestive system in adults: A review

Figure 1 Gastroblastoma in a 19-year-old patient. A and B: The tumor involves the muscularis propria of the antrum (20 ×); C: The tumor shows a biphasic histology with spindle stromal component more prominent in left lower of the image (40 ×); D: The high-magnification image shows the epithelial cells with glandular formation (400 ×); E: Cytoketatin staining (AE1/3) labels the epithelial cells but not the mesenchymal component (200 ×).

Figure 2 Mixed epithelial mesenchymal hepatoblastoma in an adult patient, showing a heterogeneous mix of epithelial and mesenchymal components. Well differentiated fetal-type epithelial component is characterized by their eosinophilic cytoplasm and cords or nests-like growth reminiscent of normal liver architecture. The mesenchymal part shows heterologous osteoid elements (100 ×).

Figure 3 Pancreatoblastoma in the pancreatic head of a 42-year-old male patient. A: The tumor is composed of acinar and ribbonlike morphology composed of relatively monotonous cells with basophilic nuclei, mimicking a pancreatic endocrine tumor (100 ×); B: In a few foci, squamoid nests, consisting of circumscribed whorled nests of polygonal cells with abundant eosinophilic cytoplasm and a squamous appearance, are present (200 ×).