Systematic Reviews
Copyright ©The Author(s) 2024.
World J Gastrointest Surg. Feb 27, 2024; 16(2): 554-570
Published online Feb 27, 2024. doi: 10.4240/wjgs.v16.i2.554
Figure 1
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Figure 1 PRISMA flowchart for selection of the studies.
Figure 2
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Figure 2 Risk-of-bias assessments for prospective clinical trials included in the meta-analysis. A: Risk-of-bias summary; B: Risk-of-bias graph. +: Low risk of bias; ?: Unclear risk of bias; -: High risk of bias.
Figure 3
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Figure 3 Forest plot of recurrence free survival and overall survival for pairwise meta-analysis. A: Recurrence free survival; B: Overall survival. HT: Hepatectomy; HAIC: Hepatic artery infusion chemotherapy; RT: Radiotherapy; TACE: Transarterial chemoembolization; HR: Hazard ratio; CI: Confidence interval.
Figure 4
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Figure 4 Network diagram of eligible comparisons for recurrence free survival and overall survival. A: Recurrence free survival; B: Overall survival. HT: Hepatectomy; HAIC: Hepatic artery infusion chemotherapy; RT: Radiotherapy; TACE: Transarterial chemoembolization.
Figure 5
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Figure 5 Convergence of the three chains established by trace and the Brooks-Gelman-Rubin diagnostic for recurrence free survival and overall survival. A and B: Recurrence free survival; C and D: Overall survival. HT: Hepatectomy; HAIC: Hepatic artery infusion chemotherapy; RT: Radiotherapy; TACE: Transarterial chemoembolization.
Figure 6
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Figure 6 Hazard ratio along with 95% confidence interval for recurrence free survival and overall survival for each adjuvant therapy compared with hepatectomy. A: Recurrence free survival; B: Overall survival. HT: Hepatectomy; HAIC: Hepatic artery infusion chemotherapy; RT: Radiotherapy; TACE: Transarterial chemoembolization; CI: Confidence interval.
Figure 7
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Figure 7 Pooled estimates of the network meta-analysis. HT: Hepatectomy; HAIC: Hepatic artery infusion chemotherapy; RT: Radiotherapy; TACE: Transarterial chemoembolization; RFS: Recurrence free survival; OS: Overall survival.
Figure 8
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Figure 8 Cumulative ranking plot and surface under the cumulative ranking curve values for recurrence free survival and overall survival. A: Recurrence free survival; B: Overall survival. HT: Hepatectomy; HAIC: Hepatic artery infusion chemotherapy; RT: Radiotherapy; TACE: Transarterial chemoembolization; SUCRA: Surface under the cumulative ranking curve.
Figure 9
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Figure 9 The node-splitting approach demonstrated consistency between the direct and indirect evidence for recurrence free survival and overall survival. A: Recurrence free survival; B: Overall survival. HT: Hepatectomy; RT: Radiotherapy; TACE: Transarterial chemoembolization; CI: Confidence interval.
Figure 10
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Figure 10  Funnel plot and Egger’s tests for the included studies in terms of recurrence free survival and overall survival. A: Recurrence free survival; B: Overall survival. HT: Hepatectomy; HAIC: Hepatic artery infusion chemotherapy; RT: Radiotherapy; TACE: Transarterial chemoembolization.