Successful resection of colonic metastasis of lung cancer after colonic stent placement: A case report and review of the literature

Figure 1 Abdominal contrast-enhanced computed tomography. A: Coronal section shows a mass lesion (white arrow) protruding into the lumen of the splenic flexure with a slight contrast enhancement; B: Horizontal section shows a mass (white arrow) occupying 3/4 the circumference of the lumen.

Figure 2 Colonoscopy and subsequent gastrografin enema. A: Colonoscopy depicts a mass protruding into the lumen covered with smooth and reddish mucosa, the scope could not be advanced through the lesion; B: Gastrografin enema shows an apple core sign with luminal narrowing (white arrow), approximately 3 cm in length, in the descending colon.

Figure 3 Macroscopic and microscopic findings. A: A circumferential protruding tumor in the descending colon with stent-induced mucosal changes; B: Hematoxylin and eosin (HE) staining (× 40), the tumor shows the appearance of squamous cell carcinoma, mainly confined to the submucosal layer; C-E: Immunohistochemical staining for CK5/6 (C, × 200), p40 (D, × 200), and CDX2 (E, × 400). The tumor cells are positive for CK5/6 and p40, and negative for CDX2; F: HE staining of the lung biopsy specimen of the patient (× 40). The patient was diagnosed with squamous cell lung cancer.