Harnessing interventions during the immediate perioperative period to improve the long-term survival of patients following radical gastrectomy

Figure 1 Potential perioperative interventions for improving the survival of gastric cancer patients following curative resection. A robust biological rationale supports the likely antimetastatic efficacy of various interventions during the perioperative period, including appropriate operation, anesthesia and analgesia selection, approaches to limit stress-inflammatory responses and preservation or activation of anticancer immunity. The figure in this review was created with BioRender.com. NSAIDs: Nonsteroidal anti-inflammatory drugs; TLR: Toll-like receptor; TIVA: Total intravenous anesthesia.