Significance of carcinoembryonic antigen detection in the early diagnosis of colorectal cancer: A systematic review and meta-analysis

Figure 1 Preferred Reporting Items for Systematic Reviews and Meta-Analyses flow chart. RCT: Randomized controlled trial.

Figure 2 Risk of bias and applicability concerns of all studies.

Figure 3 Risk of bias assessment of every study.

Figure 4 Forest plot of sensitivity of carcinoembryonic antigen. TP: True positive; FP: False positive; FN: False negative; TN: True negative; 95%CI: 95% confidence interval.

Figure 5 Forest plot of sensitivity and specificity of carcinoembryonic antigen. TP: True positive; FP: False positive; FN: False negative; TN: True negative; 95%CI: 95% confidence interval.

Figure 6 Forest plot of the sensitivity and specificity of carcinoembryonic antigen in high-quality trials. TP: True positive; FP: False positive; FN: False negative; TN: True negative; 95%CI: 95% confidence interval.