Laparoscopic-assisted endoscopic full-thickness resection of a large gastric schwannoma: A case report

Figure 1 Preoperative endoscopy and endoscopic ultrasonography. A: Upper digestive tract endoscopy showing a submucosal tumor along the greater curvature of the anterior gastric antrum wall; B: Endoscopic ultrasonography showing a mass within the gastric antrum, which originated from the muscularis propria; C: Gastroscopy 3 mo after surgery revealing appropriate incision healing.

Figure 2 Computed tomography scan. A: Computed tomography showing an oval mass in the antrum of the stomach, with intracavitary growth; B: Enhanced computed tomography shows obvious enhancement of the mass in the arterial phase.

Figure 3 Specimen after surgery, hematoxylin and eosin-stained pathological sections, and immunohistochemistry. A: The resected tumor; B and C: The tumor comprises intertwined bundles of spindle cells with tapered nuclei; mitotic figures are rare. Lymphocyte infiltration is observed in the tumor tissue, and a characteristic peripheral lymphoid cuff is present (B: 4 × C: 20 ×); D-I: Immunohistochemical staining of the gastric mass confirming a gastric schwannoma with positive staining for S-100 protein (I) and negative staining for α-smooth muscle actin (D), DOG-1 (E), CD34 (F), CD117 (G), and desmin (H).

Figure 4 Timeline of case occurrence. CT: Computed tomography; EUS: Endoscopic ultrasonography.