Reappraisal of surgical decision-making in patients with splenic sclerosing angiomatoid nodular transformation: Case series and literature review

Figure 1 Schema of patient selection process and splenic tumor classification. SANT: Sclerosing angiomatoid nodular transformation; HCC: Hepatocellular carcinoma; NTUH: National Taiwan University Hospital.

Figure 2 Typical image features of sclerosing angiomatoid nodular transformation. A-C: Computed tomography (CT), non-contrast (A), arterial phase (B), venous phase (C) (Case 2); D and E: Magnetic resonance imaging (MRI), MRI T1 (D), MRI T2 (E) (Case 1); F: Positron emission tomography-CT (Case 3).

Figure 3 Non-sclerosing angiomatoid nodular transformation tumors compared with sclerosing angiomatoid nodular transformation base on magnetic resonance imaging T2 signals. A: Sclerosing angiomatoid nodular transformation (hypointensity); B: Hemangioma (hyperintensity); C: Lymphoma (hypointensity); D: Metastasis, central necrosis (hyperintensity).

Figure 4 Image comparison between splenic lymphoma and sclerosing angiomatoid nodular transformation. A: Computed tomography, homogenous splenomegaly; B: Computed tomography, multifocal lesion (splenic lymphoma); C: Magnetic resonance imaging T2, solitary mass with spoke wheel pattern (splenic lymphoma); D: Magnetic resonance imaging T2, solitary mass with spoke wheel pattern (sclerosing angiomatoid nodular transformation).