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©2013 Baishideng Publishing Group Co., Limited. All rights reserved.
World J Gastrointest Surg. May 27, 2013; 5(5): 138-145
Published online May 27, 2013. doi: 10.4240/wjgs.v5.i5.138
Published online May 27, 2013. doi: 10.4240/wjgs.v5.i5.138
Management of potentially resectable colorectal cancer liver metastases
Fausto Meriggi, Paola Bertocchi, Alberto Zaniboni, Oncology Department, Istituto Ospedaliero Fondazione Poliambulanza, 25124 Brescia, Italy
Author contributions: Meriggi F, Bertocchi P and Zaniboni A contribuited equally to this paper.
Correspondence to: Alberto Zaniboni, MD, Oncology Department, Istituto Ospedaliero Fondazione Poliambulanza, via Bissolati 57, 25124 Brescia, Italy. zanib@numerica.it
Telephone: +39-30-3515553 Fax: +39-30-35152224
Received: February 24, 2013
Revised: March 28, 2013
Accepted: April 27, 2013
Published online: May 27, 2013
Revised: March 28, 2013
Accepted: April 27, 2013
Published online: May 27, 2013
Core Tip
Core tip: Colorectal cancer is a very common malignancy and its incidence is rapidly increasing worldwide. Of all patients with metastatic colorectal cancer, up to 77% have a liver-only disease and about 10%-20% of them are considered resectable at the time of diagnosis. Surgery actually still represents the best option of treatment, but new strategies such as perioperative chemotherapy and targeted therapies are emerging with promising results. However, optimal management requires a multidisciplinary approach, both local and systemic. This review aims to critically analyze the management of potentially resectable colorectal liver metastases.