Copyright
©The Author(s) 2018.
World J Diabetes. Dec 15, 2018; 9(12): 239-251
Published online Dec 15, 2018. doi: 10.4239/wjd.v9.i12.239
Published online Dec 15, 2018. doi: 10.4239/wjd.v9.i12.239
Group | Retinal layers | Total thickness of the retina | |||||
Layer rods and cones | Outer nuclear layer | Outer plexiform layer | Inner nuclear layer | Inner plexiform layer | Ganglion cell layer | ||
Control (group 1) | 36.31 ± 5.11 | 56.43 ± 1.72 | 9.85 ± 1.68 | 25.82 ± 0.76 | 38.93 ± 4.79 | 17.82 ± 0.72 | 185.16 ± 9.42 |
Diabetes at 30 d (group 2) | 28.65 ± 3.44a | 51.62 ± 6.51a | 11.46 ± 1.59 | 26.1 ± 1.55 | 40.21 ± 7.14 | 15.98 ± 1.37a | 174.00 ± 2.93a |
Diabetes at 60 d (group 3) | 28.38 ± 1.43a | 56.87 ± 5.30 | 9.69 ± 1.04c | 26.24 ± 0.95a | 39.94 ± 7.10 | 14.65 ± 2.05a | 175.77 ± 5.22a |
Group | Layers of the retina | |||||
Inner nuclear layer | Ganglion cell layer | |||||
1000 at 1 mm2 | % of Ki-67 positive cells | 1000 at 1 mm2 | % of Ki-67 positive cells | |||
All cells | Ki-67 positive cells | All cells | Ki-67 positive cells | |||
Control (group 1) | 28.60 ± 2.11 | 7.25 ± 0.93 | 25.46 ± 3.53 | 7.71 ± 1.01 | 0.99 ± 0.3 | 12.98 ± 3.24 |
Diabetes at 30 d (group 2) | 27.94 ± 1.14 | 4.92 ± 0.92a | 17.82 ± 3.79a | 5.45 ± 0.78a | 0.42 ± 0.18a | 7.83 ± 3.11a |
Diabetes at 60 d (group 3) | 29.24 ± 2.56 | 4.55 ± 1.5a | 15.4 ± 4.76a | 6.19 ± 0.79a | 0.59 ± 0.3a | 9.95 ± 5.12 |
- Citation: Danilova I, Medvedeva S, Shmakova S, Chereshneva M, Sarapultsev A, Sarapultsev P. Pathological changes in the cellular structures of retina and choroidea in the early stages of alloxan-induced diabetes. World J Diabetes 2018; 9(12): 239-251
- URL: https://www.wjgnet.com/1948-9358/full/v9/i12/239.htm
- DOI: https://dx.doi.org/10.4239/wjd.v9.i12.239