Copyright
©The Author(s) 2015.
World J Diabetes. Jul 25, 2015; 6(8): 1057-1064
Published online Jul 25, 2015. doi: 10.4239/wjd.v6.i8.1057
Published online Jul 25, 2015. doi: 10.4239/wjd.v6.i8.1057
Vitamin D status | 25OHD3 (nmol/L)1 |
Sufficient (optimal) | > 75 |
Insufficient | 50-75 |
Deficient | < 50 |
Ref. | No. of subjects | Age, mean or range | Trial outcome |
(A) | |||
Jorde et al[47] | 10229 | 58 | 25OHD negatively associated with BMI |
Lee et al[49] | 95 | 68, 47-91 | 25OHD negatively related to BMI |
Lagunova et al[50] | 102 | 8-19 | ↑ prevalence of Vit D Def. (19%) and insuff. (> 50%) in obese |
Suijder et al[60] | 453 | > 65 | ↑ BMI is associated with ↓ 25OHD |
(B) | |||
Chiu et al[27] | 125 | 26 | +ve relation between 25OHD and insulin sensitivity |
Nunlee-Bland et al[51] | 34 | 10-20 | ↓ 25OHD is associated with insulin resistance |
Shankar et al[61] | 12719 | > 20 | ↓ 25OHD is associated with pre-diabetes state |
(C) | |||
Song et al[63] | 76220 | meta-analysis | inverse relation between 25OHD and risk for T2DM |
Afzal et al[64] | 9841 | 48-65 | ↓ 25OHD is associated with ↑ risk for T2DM |
Pittas et al[65] | 95243 | meta-analysis | ↓ incidence of T2DM in highest vs lowest 25OHD |
Buijsse et al[69] | 53088 | 50.9 | HR of T2DM is ↓ with ↑ in 25OHD |
- Citation: Al-Shoumer KA, Al-Essa TM. Is there a relationship between vitamin D with insulin resistance and diabetes mellitus? World J Diabetes 2015; 6(8): 1057-1064
- URL: https://www.wjgnet.com/1948-9358/full/v6/i8/1057.htm
- DOI: https://dx.doi.org/10.4239/wjd.v6.i8.1057