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©The Author(s) 2015.
World J Diabetes. May 15, 2015; 6(4): 642-647
Published online May 15, 2015. doi: 10.4239/wjd.v6.i4.642
Published online May 15, 2015. doi: 10.4239/wjd.v6.i4.642
Table 1 Frequencies of single nucleotide polymorphisms of cytokines in various ethnic groups
S no | Ethnic group | n | IL6 -174G/C genotype frequency | Ref. | ||
GG (%) | GC (%) | CC (%) | ||||
1 | Diabetic Turkish | 96 | 83.9 | 16.1 | Karadeniz et al[5] | |
2 | Diabetic Indians | 40 | 57 | 28 | 15 | Mukhopadhyaya et al[33] |
Healthy Indians | 40 | 30 | 33 | 37 | ||
3 | Diabetic Finnish | 737 | 61 | 39 | Razquin et al[27] | |
4 | Diabetic Mexicans | 90 | 76.7 | 20 | 3.3 | Guzmán-Guzmán et al[34] |
IL6 -572 G/C allele frequency | ||||||
GG (%) | GC (%) | CC (%) | ||||
5 | Healthy Chinese | 581 | 3.74 | 39.8 | 56.4 | Zhou et al[35] |
6 | Diabetic Mexicans | 90 | 61.1 | 30 | 8.9 | Guzmán-Guzmán et al[34] |
7 | Healthy Caucasians | 677 | 6.2 | 39 | 54.8 | Paik et al[36] |
TNFα -308G/A allele frequency | ||||||
GG (%) | GA (%) | AA (%) | ||||
8 | Diabetic Mexicans | 278 | 76 | 24 | Pérez-Martínez et al[31] | |
9 | Diabetic Caucasians | 350 | 87 | 13 | Chan et al[37] | |
10 | Diabetic Indians | 40 | 87.5 | 5 | 7.5 | Mukhopadhyaya et al[33] |
Healthy Indians | 40 | 92.5 | 0 | 7.5 | ||
TNFα -238 G/A allele frequency | ||||||
GG (%) | GA (%) | AA (%) | ||||
11 | Healthy Iranians | 202 | 79.3 | 19.2 | 1.5 | Hedayati et al[38] |
12 | Diabetic Canadians | 123 | 85.4 | 14.6 | Fontaine-Bisson et al[14] | |
13 | Diabetic Chileans | 230 | 90 | 10 | 0 | Santos et al[30] |
RETN -420 G/C allele frequency | ||||||
CC % | GC% | GG% | ||||
14 | Diabetic Japanese | 161 | 47.2 | 46 | 6.8 | Hishida et al[39] |
Healthy Japanese | 2491 | 42.6 | 43.7 | 13.7 | ||
15 | Diabetic Han Chinese | 318 | 60 | 40 | Chi et al[40] | |
Healthy Han Chinese | 370 | 61.5 | 38.5 | |||
16 | Diabetic Finnish | 258 | 65 | 35 | Kunnari et al[41] | |
Healthy Finnish | 494 | 73 | 27 | |||
ADIPOQ -11377 G/C allele frequency | ||||||
17 | Diabetics White | 503 | 79 | 21 | Chiodini et al[42] | |
18 | Diabetic Han Chinese | 212 | 68.6 | 31.4 | Yang et al[43] | |
19 | Diabetic Germans | 365 | 71 | 29 | Schwarz et al[44] |
- Citation: Nadeem A, Mumtaz S, Naveed AK, Aslam M, Siddiqui A, Lodhi GM, Ahmad T. Gene-gene, gene-environment, gene-nutrient interactions and single nucleotide polymorphisms of inflammatory cytokines. World J Diabetes 2015; 6(4): 642-647
- URL: https://www.wjgnet.com/1948-9358/full/v6/i4/642.htm
- DOI: https://dx.doi.org/10.4239/wjd.v6.i4.642