HLA alleles may serve as a tool to discriminate atypical type 2 diabetic patients

Table 1 Reference values (mmol/L) of parameters stratified

Dyslipidemia parameters	Desirable	Limit	Abnormal
Total cholesterol	< 5.2	5.2-6.19	> 6.2
HDL	> 1.2	1.2-0.9	< 0.9
LDL	< 3.4	3.4-4.0	> 4.1
Triglycerides	2.3	2.3-2.99	> 3.0

HDL: High density lipoproteins; LDL: Low density lipoproteins.

Table 2 Phenotypic classification of dyslipidemia

	Total Cholesterol	LDL	Triglycerides	HDL
Hypercholesterolemia	≥ 6.2	≥ 4.1	< 2.3
Combined hyperlipidemia		≥ 4.1	≥ 2.3
Hipo alfa lipoproteinemia		> 4	< 2.3	< 1

Reference values (mmol/L). HDL: High density lipoproteins; LDL: Low density lipoproteins.

Table 3 Clinical characteristics expressed by media and standard deviation

	Sample A n = 93	Sample B n = 106	P value
Age (yr)	62.01 ± 11.65	66.02 ± 9.55	0.060
Age onset (yr)	47.18 ± 12.61	49.54 ± 10.13	0.131
Years of evolution	16.41 ± 9.72	15.45 ± 9.22	0.528
BMI (kg/mts2)	32.07 ± 5.26	31.45 ± 5.95	0.430
HbA1c (%)1	8.31 ± 1.87	8.16 ± 1.65	0.545
Total cholesterol (nmol/L)	5.07 ± 1.1	5.56± 1.5	0.010a
HDL (nmol/L)	1.23 ± 0.3	1.33 ± 0.3	0.010a
LDL (nmol/L)	2.86 ± 0.9	3.38 ± 1.7	0.009b
Triglycerides (nmol/L)	2.29 ± 1.4	2.81 ± 0.9	0.864
TG/HDL	2.10 ± 1.5	1.96 ± 2.0	0.572

¹At beginning of the study. Sample A vs Sample B:

^aP < 0.05,

^bP < 0.01 for all parameters. BMI: Body mass index; LDL: Low-density lipoprotein-cholesterol; HDL: High-density lipoprotein-cholesterol; TG/HDL: Insulin resistance index; HbA1c (%): Glycated hemoglobin percentage.

Table 4 χ² analysis

	OR	95%CI	P value
Dyslipidemia	0.45	0.24-0.82	< 0.01
Total cholesterol	0.48	0.27-0.84	< 0.01
HDL	1.84	1.04-3.23	< 0.05
LDL	0.50	0.28-0.91	< 0.05

LDL: Low-density lipoprotein-cholesterol; HDL: High-density lipoprotein-cholesterol.