Rationale, design and baseline patient characteristics of the optimal type 2 diabetes management including benchmarking and standard treatment study in Greece

Table 1 History data of the study population in Greece

Variable	Value
Age (yr)	64 ± 11
Male gender	457 (57.3)
Positive family history of diabetes	483 (64.2)
Family history of premature heart disease	213 (28.4)
Time since diagnosis of diabetes (yr)	9.2 ± 8.3
Age at diagnosis of diabetes (yr)	54 ± 11
Smoking status
Current smokers	194 (24.3)
Ex-smokers	171 (21.4)
Non-smokers	432 (54.2)

Data are expressed as absolute numbers (percentage) or mean ± SD.

Table 2 Macrovascular and microvascular complications of diabetes and concomitant diseases of the study population in Greece n (%)

Clinical condition	Value
Hypertension	615 (77.2)
Coronary heart disease	186 (23.8)
Stroke	50 (6.3)
Peripheral artery disease	85 (11.1)
Amputation	2 (0.3)
Proteinuria	38 (5.6)
End-stage renal disease	1 (0.1)
Retinopathy	54 (7.2)

Table 3 Baseline clinical characteristics of the study population in Greece (mean ± SD)

Variable	Value
Height (cm)	167 ± 9
Weight (kg)	83 ± 16
Body mass index (kg/m2)	29.6 ± 5.0
Waist circumference (cm)	103 ± 14
Systolic blood pressure (mmHg)	138 ± 17
Diastolic blood pressure (mmHg)	80 ± 9

Table 4 Treatment of the study population in Greece

Treatment	n (%)
Antidiabetic	740 (92.9)
Insulin	145 (19.6)
Biguanide (metformin)	519 (70.1)
Sulfonylurea	343 (46.4)
Glitazone	142 (19.2)
Others	104 (14.1)
Lipid-lowering	553 (69.4)
Statin	517 (93.5)
Ezetimibe	53 (9.6)
Fibrate	17 (3.1)
Others	43 (7.8)
Antihypertensive	591 (96.11)
ARBs	330 (55.8)
ACEi	202 (34.2)
CCBs	242 (40.9)
Beta-blockers	179 (30.3)
Alpha-blockers	13 (2.2)
Diuretics	220 (37.2)
Others	19 (3.2)
Anti-obesity	40 (5.0)
Aspirin	298 (37.4)

¹The percentage value refers to patients with hypertension. ARBs: Angiotensin receptor blockers; ACEi: Angiotensin converting enzyme Inhibitors; CCBs: Calcium channel blockers.

Table 5 Laboratory evaluation of the study population in Greece (mean ± SD)

Variable	Values
Glucose (mg/dL)	138 ± 47
HbA1c (%)	7.2 ± 1.3
LDL-C (mg/dL)	112 ± 35
HDL-C (mg/dL)	50 ± 13
TC (mg/dL)	192 ± 42
TG (mg/dL)	154 ± 85
Albuminuria (mg/g Cr)	66.6 ± 249.2

HbA1c: Glycosylated hemoglobin; LDL-C: Low density lipoprotein cholesterol; HDL-C: High density lipoprotein cholesterol; TC: Total cholesterol; TG: Triglycerides; Cr: Creatinine.