Continuous positive airway pressure to improve insulin resistance and glucose homeostasis in sleep apnea

Table 1 Summary of the 3 randomised controlled trials which examined the role of continuous positive airway pressure on glucose homeostasis

Author	Patients	Duration	Methods	Results
Lam et al[10]	61	1 wk	Short insulin tolerance test	Increase in insulin sensitivity after 1 wk of CPAP use. Further improvement after 12 wk in subjects with BMI < 25 kg/m2
		12 wk
West et al[11]	42	3 mo	Hyperinsulinemic euglycemic clamp, HOMA index, HbA1C	No difference after 3 mo of APAP use
Coughlin et al[12]	24	6 wk	Fasting glucose, insulin, HOMA index	No difference

CPAP: continuous positive airway pressure; APAP: automatic positive airway pressure; BMI: body mass index; HbA_1c: haemoglobin A_1c.