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©The Author(s) 2025.
World J Diabetes. Aug 15, 2025; 16(8): 105228
Published online Aug 15, 2025. doi: 10.4239/wjd.v16.i8.105228
Published online Aug 15, 2025. doi: 10.4239/wjd.v16.i8.105228
Table 1 Farnesoid X receptor potential binding site sequence and score of human binding immunoglobulin protein gene promoter region (farnesoid X receptor binding site analysis software)
Classic sequence | Position of positive and negative chain sequence (bp) | Score | Z score | P value | E value | Half point E value | Binding site sequence (5’-3’) |
DR2 | 1374 (-) | 0.928 | 0.0006372 | GGGTCAGGAGATCA | |||
DR6 | 376 (-) | 0.824 | 0.0084952 | GGATCACGAGGTCA | |||
DR4 | 1382 (-) | 0.802 | 0.0140067 | GGATCACGGGGTCA | |||
IR8 | 66 (-) | 0.765 | 0.0170365 | GGGTCACTCCTGGGACCT | |||
DR1 | 2159 (-) | 0.727 | 0.0287146 | GGGGCAAAGGTTA | |||
DR8 | 750 (-) | 0.716 | 0.0254571 | GGGTCAGAAGTCAGGAGA |
- Citation: Tang JY, Chong YJ, Yang L, Li X, Yang Y, Li JC, Mu J. Activation of farnesoid X receptor upregulates binding immunoglobulin protein expression and alleviates diabetic nephropathy. World J Diabetes 2025; 16(8): 105228
- URL: https://www.wjgnet.com/1948-9358/full/v16/i8/105228.htm
- DOI: https://dx.doi.org/10.4239/wjd.v16.i8.105228