Therapeutic effectiveness of intratympanic and retroauricular methylprednisolone sodium succinate for refractory sudden sensorineural hearing loss in diabetic patients

Table 1 Baseline data of two groups

Data	Control group (n = 40)	Research group (n = 44)	χ2/t	P value
Age (years old)	56.75 ± 7.28	55.75 ± 8.44	0.579	0.564
Sex (male/female)	24/16	23/21	0.508	0.476
Diabetes duration (years)	7.35 ± 2.13	6.68 ± 1.64	1.624	0.108
Mean arterial pressure (mmHg)	97.22 ± 11.40	99.84 ± 12.29	1.010	0.316
Body mass index (kg/m2)	22.32 ± 2.18	22.66 ± 3.58	0.519	0.605
Heart rate (beats/min)	78.45 ± 9.36	80.00 ± 7.33	0.849	0.398

Table 2 Therapeutic effectiveness of the two groups, n (%)

Curative effect	Control group (n = 40)	Research group (n = 44)	χ2	P value
Cured	5 (12.50)	9 (20.45)
Markedly effective	12 (30.00)	18 (40.91)
Effective	7 (17.50)	9 (20.45)
Ineffective	16 (40.00)	8 (18.18)
Total effectiveness	24 (60.00)	36 (81.82)	4.887	0.027

Table 3 Adverse reactions of two groups, n (%)

Adverse reactions	Control group (n = 40)	Research group (n = 44)	χ2	P value
Tympanic membrane perforation	1 (2.50)	0 (0.00)
Middle ear infections	1 (2.50)	0 (0.00)
Burning sensation	2 (5.00)	1 (2.27)
Vertigo	1 (2.50)	2 (4.55)
Tinnitus	1 (2.50)	1 (2.27)
Total	6 (15.00)	4 (9.09)	0.698	0.404