Copyright
©The Author(s) 2024.
World J Diabetes. Jul 15, 2024; 15(7): 1627-1644
Published online Jul 15, 2024. doi: 10.4239/wjd.v15.i7.1627
Published online Jul 15, 2024. doi: 10.4239/wjd.v15.i7.1627
Table 1 The top 10 country and cited country in this field
| Rank | Country/region | Documents | Country/region | Citations |
| 1 | China | 123 | United States | 5136 |
| 2 | United States | 102 | China | 2309 |
| 3 | The United Kingdom | 21 | India | 1064 |
| 4 | India | 16 | Germany | 652 |
| 5 | Germany | 13 | Portugal | 631 |
| 6 | Iran | 12 | The United Kingdom | 611 |
| 7 | Japan | 12 | Japan | 544 |
| 8 | Portugal | 11 | Australia | 458 |
| 9 | Australia | 10 | Poland | 354 |
| 10 | Italy | 10 | Ireland | 223 |
Table 2 The top 10 institutions and cited institutions related to this field
| Rank | Institution | Documents | Institution | Citations |
| 1 | Shanghai Jiao Tong University (China) | 11 | University of Miami (United States) | 967 |
| 2 | Sun Yat-sen University (China) | 11 | University of Coimbra (Portugal) | 554 |
| 3 | Harvard Medical School (United States) | 10 | Harvard University (United States) | 420 |
| 4 | University of Miami (United States) | 10 | University of Mississippi (United States) | 379 |
| 5 | University of Coimbra (Portugal) | 9 | Shanghai Jiao Tong University (China) | 365 |
| 6 | Harvard University (United States) | 8 | University of Pennsylvania (United States) | 353 |
| 7 | Tufts University (United States) | 7 | University of Illinois Urbana-Champaign (United States) | 317 |
| 8 | University of Louisville (United States) | 7 | Ohio State University (United States) | 301 |
| 9 | Zhejiang University (China) | 7 | Tufts University (United States) | 290 |
| 10 | Fudan University (China) | 6 | The Chinese University of Hong Kong (China) | 261 |
Table 3 The top 10 authors and co-cited authors related to this field
| Rank | Author | Count | Co-cited author | Co-citation |
| 1 | Aristidis Veves | 11 | David G Armstrong | 71 |
| 2 | Eugenia Carvalho | 8 | Vincent Falanga | 71 |
| 3 | Sufan Chien | 7 | Rita E Mirza | 64 |
| 4 | Georgios Theocharidis | 7 | Sabine A Eming | 58 |
| 5 | Abdollah Amini | 6 | Harold Brem | 46 |
| 6 | Mohamad Bayat | 6 | Andrew J M Boulton | 41 |
| 7 | Ana Tellechea | 6 | Savita Khanna | 41 |
| 8 | Marjana Tomic-Canic | 6 | William J Jeffcoate | 36 |
| 9 | Li Yan | 6 | Chandan K Sen | 36 |
| 10 | Irena Pastar | 5 | Anca Sindrilaru | 35 |
Table 4 The top 10 journals and co-cited journals related to this field
| Rank | Journal | Count | IF 2023 | JCR | Journal | Co-citation | IF 2023 | JCR |
| 1 | Wound Repair and Regeneration (United States) | 15 | 2.9 | Q2 | Wound Repair and Regeneration (United States) | 508 | 2.9 | Q2 |
| 2 | International Journal of Molecular Sciences (United States) | 6 | 5.6 | Q1 | Journal of Investigative Dermatology (United States) | 414 | 6.5 | Q1 |
| 3 | International Wound Journal (England) | 6 | 3.1 | Q2 | Diabetes (United States) | 369 | 7.7 | Q1 |
| 4 | Journal of Wound Care (England) | 6 | 1.9 | Q3 | Diabetes Care (United States) | 364 | 16.2 | Q1 |
| 5 | Pharmaceutics (Switzerland) | 6 | 5.4 | Q1 | Plos One (United States) | 346 | 3.7 | Q2 |
| 6 | Biomedicine & Pharmacotherapy (France) | 5 | 7.5 | Q1 | Journal of Immunology (United States) | 304 | 4.4 | Q2 |
| 7 | Journal of Investigative Dermatology (United States) | 5 | 6.5 | Q1 | Journal of Clinical Investigation (United States) | 266 | 15.9 | Q1 |
| 8 | Plos One (United States) | 5 | 3.7 | Q2 | American Journal of Pathology (United States) | 250 | 6.0 | Q1 |
| 9 | Acta Biomaterialia (England) | 4 | 9.7 | Q1 | Biomaterials (Netherlands) | 249 | 14.0 | Q1 |
| 10 | Advances in Wound Care (United States) | 4 | 4.9 | Q1 | Proceedings of The National Academy of Sciences of United States of America (United States) | 234 | 11.1 | Q1 |
Table 5 The top 10 co-cited references related to this field
| Rank | Co-cited Ref. | Count | Country |
| 1 | Vincent Falanga, 2005, Lancet, v366, p1736 | 56 | England |
| 2 | David G Armstrong, 2017, New England Journal of Medicine, v376, p2367 | 41 | United States |
| 3 | Savita Khanna, 2010, Plos One, v5 | 41 | United States |
| 4 | Paulina Krzyszczyk, 2018, Frontiers in Physiology, v9 | 31 | United States |
| 5 | Anca Sindrilaru, 2011, Journal of Clinical Investigation, v121, p985 | 30 | United States |
| 6 | Harold Brem, 2007, Journal of Clinical Investigation, v117, p1219 | 29 | United States |
| 7 | Rita E Mirza, 2013, Diabetes, v62, p2579 | 29 | Switzerland |
| 8 | Tina Lucas, 2010, Journal of Immunology, v184, p3964 | 28 | United States |
| 9 | Rita E Mirza, 2011, cytokine, v56, p256 | 28 | England |
| 10 | Wetzler C, 2000, Journal of Investigative Dermatology, v115, p245 | 28 | United States |
Table 6 The top 10 Keywords related to this field
| Rank | Keywords | Count | Centrality | Year |
| 1 | Diabetic foot ulcer | 228 | 0.37 | 2005 |
| 2 | Wound healing | 92 | 0.1 | 2010 |
| 3 | Macrophage | 75 | 0.15 | 2005 |
| 4 | Expression | 66 | 0.19 | 2004 |
| 5 | Inflammation | 52 | 0.1 | 2010 |
| 6 | Cell | 50 | 0.04 | 2009 |
| 7 | Activation | 43 | 0.05 | 2013 |
| 8 | Macrophage polarization | 43 | 0.04 | 2018 |
| 9 | Angiogenesis | 40 | 0.25 | 2005 |
| 10 | In vitro | 26 | 0.12 | 2007 |
Table 7 17 keyword clusters of research involving macrophage-related diabetic foot ulcers
| Cluster ID | Size | Silhouette | Mean (year) | Label (LSI) | Label (LLR) | Label (MI) |
| 0 | 64 | 0.63 | 2014 | Wound healing; diabetes mellitus; diabetic foot ulcer; low level laser therapy; tensiometerical properties | chronic wounds; local treatment; immunohistochemical markers; diabetic foot ulcers; venous leg ulcers | Diabetes mellitus (22.75, 1.0E-4); chronic wounds (13.74, 0.001); wound healing (12.48, 0.001); histology (11.05, 0.001); wound closure (7.36, 0.01) | Skin and wound care (0.76); tgf-beta (0.76); metfo |
| 1 | 49 | 0.673 | 2014 | Wound healing; adipose tissue; extracellular vesicles; diabetic foot ulcer; small extracellular vesicles | endothelial progenitor; coronary artery; griffonia simplicifolia; biomimetic hydrogels; tissue engineering | Obesity (9.64, 0.005); expression (9.59, 0.005); coronary artery disease (9.28, 0.005); adipose tissue (9.28, 0.005); endothelial progenitor cells (9.28, 0.005) | Type 2 (0.42); griffonia simplicifolia i b4 (0.42) |
| 2 | 48 | 0.682 | 2015 | Wound healing; diabetic foot ulcer; stromal cells; astragali radix; diabetic wound healing | foot ulcer; mouse model; growth factor; mice; dysfunction | Mesenchymal stem (10.73, 0.005); growth factor (8.23, 0.005); neuropeptides (7.06, 0.01); Chinese medicine (7.06, 0.01); neurotensin (7.06, 0.01) | Animal models (0.27); biologics (0.27); acellular |
| 3 | 39 | 0.738 | 2018 | Wound healing; tensiometric properties; microbial flora; curcumin-loaded superparamagnetic iron oxide nanoparticles; pseudomonas aeruginosa | diabetic foot ulcer; chronic wound; siRNA delivery; lipid nanoparticle; lipidoid nanoparticle | Diabetic wounds (12.93, 0.001); tlr4 (9.12, 0.005); adaptive immunity (5.52, 0.05); siRNA delivery (5.52, 0.05); antibacterial (5.52, 0.05) | Macrophage polarisation (0.44); cell penetrating p |
| 4 | 37 | 0.751 | 2012 | Diabetic foot; wound healing; tumour necrosis factor alpha; foot ulcer; endothelial progenitor | diabetic foot ulcer; foot ulcer; endothelial progenitor; human fibroblasts; tumor necrosis factor-alpha | Diabetic foot (12.14, 0.001); foot (8, 0.005); in vivo (7.47, 0.01); endothelial growth factor (7.05, 0.01); chronic wounds (5.35, 0.05) | Inflammatory arthritis (0.73); surgery (0.73); neu |
| 5 | 37 | 0.871 | 2010 | Extracellular matrix; metal-polyphenol capsule; diabetic wound healing; situ tissue regeneration; split-thickness skin graft | foot ulcers; skin; matrix metalloproteinases; mechanisms; angiogenesis | Double blind (15.79, 1.0e-4); colony stimulating factor (15.79, 1.0e-4); wound healing (11.55, 0.001); in situ tissue regeneration (10.51, 0.005); diabetic neuropathy (10.51, 0.005) | Intraepidermal nerve fibers (0.29); growth factor |
| 6 | 35 | 0.921 | 2006 | Controlled trials; granulocyte colony-stimulating factor; intensive care; acute respiratory distress syndrome; two-hit model | granulocyte-macrophage colony-stimulating factor; diabetic foot infection; colony-stimulating factor; intensive care; two-hit model | Sepsis (17.44, 1.0e-4); acute respiratory distress syndrome (8.68, 0.005); controlled trials (8.68, 0.005); granulocyte colony-stimulating factor (g-csf) (8.68, 0.005); cancer (8.68, 0.005) | Acute respiratory distress syndrome (0.03); control |
| 7 | 30 | 0.732 | 2014 | Wound healing; innate immunity; gene expression; diabetic foot ulcer; diabetic wound | activation; inflammation; diabetic foot disease; neuropeptide substance; skin substitutes | Activation (11.88, 0.001); angiogenesis (5.61, 0.05); nlrp3 inflammasome (5.1, 0.05); inflammation (4.55, 0.05); notch (4.33, 0.05) | Notch (0.51); alveolar macrophages (0.51); behavior |
| 8 | 30 | 0.804 | 2017 | Differentiation; senescence; growth arrest; miR 145; miR expression | presenting cells; intracellular bacteria; staphylococcus aureus; diabetic ulcers; biomimetic hydrogels | Antigen (11.18, 0.001); intracellular bacteria (11.18, 0.001); presenting cells (11.18, 0.001); mesenchymal stem cells (6.83, 0.01); differentiation (6.09, 0.05) | Bm-mscs (0.23); collagen i (0.23); diabetic ulcer |
| 9 | 29 | 0.816 | 2009 | Angiogenesis; skin; tissue; hyperbaric oxygen; osteoradionecrosis | amputation; matrix metalloproteinases; risk factors; binding; potent gelatinase | Amputation (17.25, 1.0e-4); management (11.48, 0.001); angiogenesis (10.17, 0.005); randomized controlled trial (7.78, 0.01); amputations (7.78, 0.01) | Utility (0.21); nanomedicine (0.21); white matter |
| 10 | 27 | 0.676 | 2016 | Wound healing; diabetic foot; no-option critical limb ischemia; cell therapy; peripheral blood mononuclear cells | diabetic foot ulcer; epidermal growth factor; oxidative stress; single cell sequence; angiogenic properties | Migration inhibitory factor (11.07, 0.001); signaling pathway (7.38, 0.01); association (7.38, 0.01); miRNAs-mRNA (5.53, 0.05); synergistic effect (5.53, 0.05) | MiRNAs-mRNA (0.24); synergistic effect (0.24); pat |
| 11 | 23 | 0.865 | 2016 | Chronic wound; nanocomposite hydrogels; rnos eradication; peripheral blood mononuclear cells; wound healing | macrophage polarization; tissue regeneration; diabetic foot; immune system; wound healing | Rnos eradication (12.46, 0.001); immunoregulation (12.46, 0.001); nanocomposite hydrogels (12.46, 0.001); herb-derived (12.46, 0.001); chronic wound repairing (12.46, 0.001) | Immune centric revolution (0.05); revascularization |
| 12 | 11 | 1 | 2004 | Antimicrobial peptides; microbicides; sexually transmitted infections | Microbicides (13.17, 0.001); sexually transmitted infections (13.17, 0.001); antimicrobial peptides (13.17, 0.001); wound healing (0.25, 1.0); inflammation (0.15, 1.0) | Wound healing (0.04); inflammation (0.02); macroph |
| 13 | 6 | 1 | 2008 | Positron emission tomography; fluorodeoxyglucose; infection; inflammation | Fluorodeoxyglucose (12.49, 0.001); positron emission tomography (9.72, 0.005); infection (6.49, 0.05); inflammation (3.09, 0.1); wound healing (0.34, 1.0) | Wound healing (0.03); inflammation (0.02); macroph |
| 14 | 2 | 1 | 2013 | Positron emission tomography; diabetic foot infections; chronic osteomyelitis; 18F-FDG PET/CT; leukocyte scintigraphy; rheumatoid arthritis; joint replacement; bone scintigraphy; nuclear medicine; hybrid pet | Leukocyte scintigraphy (10.49, 0.005); nuclear medicine (10.49, 0.005); bone scintigraphy (10.49, 0.005); chronic osteomyelitis (10.49, 0.005); joint replacement (10.49, 0.005) | Wound healing (0.03); inflammation (0.01); leukocyte |
| 15 | 1 | 0 | 2020 | Diabetic kidney disease; kk-a(y)mouse; sglt2 inhibitor; tofogliflozin | Kk (11.99, 0.001); a (y) mouse (11.99, 0.001); sglt2 inhibitor (11.99, 0.001); tofogliflozin (11.99, 0.001); diabetic kidney disease (9.22, 0.005) | Wound healing (0.03); inflammation (0.02); macroph |
| 16 | 1 | 0 | 2022 | Glomerulonephropathy; laminin alpha 2; mechanosensitive protein; mechanotransduction; podocyte mechanics | Mechan transduction (11.99, 0.001); laminin alpha 2 (11.99, 0.001); mechanosensitive protein (11.99, 0.001); podocyte mechanics (11.99, 0.001); glomerulonephropathy (11.99, 0.001) | Wound healing (0.03); inflammation (0.02); macroph |
- Citation: Wen JP, Ou SJ, Liu JB, Zhang W, Qu YD, Li JX, Xia CL, Yang Y, Qi Y, Xu CP. Global trends in publications regarding macrophages-related diabetic foot ulcers in the last two decades. World J Diabetes 2024; 15(7): 1627-1644
- URL: https://www.wjgnet.com/1948-9358/full/v15/i7/1627.htm
- DOI: https://dx.doi.org/10.4239/wjd.v15.i7.1627