p66Shc-mediated oxidative stress is involved in gestational diabetes mellitus

Table 1 Primer sequences

Primers	Forward	Reverse
p66Shc	5’-GCCAAAGACCCTGTGAATCAG-3’	5’-GTATTGTTTGAAGCGCAACTCG-3’
Drp1	5’-TGCCGTGAACCTGCTAGATG-3’	5’-GCCTTTGGCACACTGTCT TG-3
β-actin	5’-CTCACCATGGATGATGATATCGC-3’	5’-AGG AATCCTTCTGACCCATGC-3’

Drp1: Dynamin-related protein 1.

Table 2 Clinical characteristics of the study patients

Characteristic	Control group, n = 15	GDM group, n = 15
Maternal age in yr	31.8 ± 0.77	32.5 ± 1.02
Gestational age in wk Pre-pregnant BMI in kg/m2	38.5 ± 0.4221.11 ± 0.40	38.3 ± 0.3524. 46 ± 0.51a
Late pregnant BMI in kg/m2	25.29 ± 0.43	30.63 ± 0.53a
FPG in mmol/L	4.17 ± 0.09	5.88 ± 0.15a

^aP < 0.001 vs control.

BMI: Body mass index; FPG: Fasting plasma glucose; GDM: Gestational diabetes mellitus.