Molecular mechanisms of insulin resistance in type 2 diabetes mellitus

doi:10.4239/wjd.v1.i3.68

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 1, Issue 3

This Article

Citation of this article

Corresponding Author of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (14974)

All Articles published online

The chart showing PDF series, HTML series, Figures (1-1) series, Tables (1-1) series.

Item

Count

PDF

1339

HTML

12977

Figures (1-1)

398

Tables (1-1)

260

Sum=14974

Jul 15, 2010 (publication date) through Feb 3, 2025

Times Cited of This Article

Times Cited (179)

Journal Information of This Article

Publication Name

World Journal of Diabetes

ISSN

1948-9358

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Topic Highlight

World J Diabetes. Jul 15, 2010; 1(3): 68-75
Published online Jul 15, 2010. doi: 10.4239/wjd.v1.i3.68

Table 1 Causes of insulin receptor substrate-1 serine phosphorylation

mTOR

p70S6 kinase

Amino acids

Hyperinsulinemia

JNK

Stress

Hyperlipidemia

Inflammation

IKK

Inflammation

TNF-α

Obesity

Inflammation

Mitochondrial dysfunction

PKCθ

Hyperglycemia

Diacylglycerol

Inflammation

mTOR: molecular target of rapamycin; JNK: c-Jun N-terminal kinase; IKK: IκB kinase; TNF: tumour necrosis factor; PKC: protein kinase C.

Citation: Saini V. Molecular mechanisms of insulin resistance in type 2 diabetes mellitus. World J Diabetes 2010; 1(3): 68-75
URL: https://www.wjgnet.com/1948-9358/full/v1/i3/68.htm
DOI: https://dx.doi.org/10.4239/wjd.v1.i3.68