Dietary Nε-(carboxymethyl) lysine affects cardiac glucose metabolism and myocardial remodeling in mice

Figure 4 Dietary N^ε-(carboxymethyl)lysine impairs glucose metabolism in mouse myocardium. A and B: mRNA levels of glucose transporter (Glut)-1 and Glut-4 in the mouse myocardium; C-G: Western blotting and its relative quantification of Glut-1, Glut-4, phospho-Akt, and phospho-AMP-activated protein kinase (AMPK) in the mouse myocardium; H: Citrate synthase (CS) activity in the mouse myocardium. dCML: Dietary N^ε-(carboxymethyl)lysine; Bcl-2: B-cell leukemia/lymphoma 2; BAX: Bcl-2-associated X; ANP: Atrial natriuretic peptide. n = 6. ^bP < 0.01, compared with the control (Ctrl) group.