New perspectives on exploitation of incretin peptides for the treatment of diabetes and related disorders

doi:10.4239/wjd.v6.i15.1285

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Nov 10, 2015 (publication date) through Jan 9, 2025

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Diabetes. Nov 10, 2015; 6(15): 1285-1295
Published online Nov 10, 2015. doi: 10.4239/wjd.v6.i15.1285

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Figure 1 Schematic depicting the major signalling pathways involved in glucose-dependent insulinotropic polypeptide, glucagon-like peptide-1, glucagon and cholecystokinin induced insulin secretion from pancreatic beta-cells. AC: Adenylyl cyclase; cAMP: Adenosine 3'-5'-cyclic monophosphate; DAG: Diacyl-glycerol; IP₃: Inositol 1,4,5-trisphosphate; PKA: Protein kinase A; PLC: Phospholipase C; CCK: Cholecystokinin.

Citation: Irwin N, Flatt PR. New perspectives on exploitation of incretin peptides for the treatment of diabetes and related disorders. World J Diabetes 2015; 6(15): 1285-1295
URL: https://www.wjgnet.com/1948-9358/full/v6/i15/1285.htm
DOI: https://dx.doi.org/10.4239/wjd.v6.i15.1285