WFS1 gene mutation associated with pediatric diabetes mellitus and congenital deafness: A case report

Figure 1 The graphical overview of the case reports. WES: Whole-exome sequencing.

Figure 2 Family pedigree.

Figure 3 Gene sequencing chromatograms. A: Proband chromatogram showing the heterozygous WFS1: c.986T>C (p.Phe329Ser) mutation indicated by arrows; B: Father chromatogram with the same heterozygous mutation indicated by arrows; C: Mother chromatogram showing absence of mutation at this locus.

Figure 4 Blood glucose monitoring during insulin therapy. A: Blood glucose levels during insulin pump therapy; B: Blood glucose levels during subcutaneous insulin injection therapy.